YRC Public Data Repository - Protein Structure Prediction

Protein:	HGNC:11830\|MIM:1...
Organism:	SPECIES UNKNOWN
Length:	234 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HGNC:11830|MIM:1....

Description	E-value	Query Range	Subject Range
gi\|60653309, gi\|... - gi\|60653309\|gb\|AAX29349.1\| thymidine kinase 1 soluble [synthetic construct], gi\|33303757\|gb\|AAQ02392...	0.0	[1..234]	[1..234]
gi\|339709, gi\|45... - pir\|\|KIHUT thymidine kinase (EC 2.7.1.21), cytosolic - human, gi\|4507519\|ref\|NP_003249.1\| thymidine...	0.0	[1..234]	[1..234]
gi\|109118477 - gi\|109118477\|ref\|XP_001107944.1\| PREDICTED: thymidine kinase 1, soluble isoform 3 [Macaca mulatta]	0.0	[1..234]	[1..234]
KITH_CRIGR - Thymidine kinase, cytosolic OS=Cricetulus griseus GN=TK1 PE=3 SV=1	0.0	[1..234]	[1..234]
gi\|94385496, gi\|... - gi\|94385496\|ref\|XP_001004635.1\| PREDICTED: similar to Thymidine kinase, cytosolic isoform 2 [Mus mus...	0.0	[1..234]	[1..234]
gi\|114670779 - gi\|114670779\|ref\|XP_001145198.1\| PREDICTED: similar to Thymidine kinase 1, soluble [Pan troglodytes]	0.0	[1..234]	[43..309]
gi\|252871, gi\|298946 - gi\|298946\|gb\|AAB26001.1\| thymidine kinase [Mus sp.], gi\|252871\|gb\|AAB22782.1\| thymidine kinase, TK {... KITH_MOUSE - Thymidine kinase, cytosolic OS=Mus musculus GN=Tk1 PE=1 SV=3	0.0	[1..234]	[1..233]

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Predicted Domain #1

Region A:
Residues: [1-234]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCINLPTVL PGSPSKTRGQ IQVILGPMFS GKSTELMRRV RRFQIAQYKC LVIKYAKDTR  60
   61 YSSSFCTHDR NTMEALPACL LRDVAQEALG VAVIGIDEGQ FFPDIVEFCE AMANAGKTVI 120
  121 VAALDGTFQR KPFGAILNLV PLAESVVKLT AVCMECFREA AYTKRLGTEK EVEVIGGADK 180
  181 YHSVCRLCYF KKASGQPAGP DNKENCPVPG KPGEAVAARK LFAPQQILQC SPAN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	2orvA
Description:	No description for 2orvA was found.

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	3.66392587433723	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
kinase activity	2.0779386406753	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
binding	1.57531761895117	bayes_pls_golite062009
DNA binding	1.22619720972604	bayes_pls_golite062009
nucleic acid binding	1.17199530230795	bayes_pls_golite062009
transcription regulator activity	1.16376707327858	bayes_pls_golite062009
transcription factor activity	0.472763834470731	bayes_pls_golite062009
protein binding	0.456164256440374	bayes_pls_golite062009
adenylate kinase activity	0.447752711852745	bayes_pls_golite062009
hydrolase activity	0.420858111948277	bayes_pls_golite062009
catalytic activity	0.101795606736461	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: