YRC Public Data Repository - Protein Structure Prediction

Protein:	HEM1_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	416 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEM1_SHEON.

Description	E-value	Query Range	Subject Range
gi\|237705171, gi... - gi\|237705171\|ref\|ZP_04535652.1\| glutamyl-tRNA reductase [Escherichia sp. 3_2_53FAA], gi\|226899928\|gb... gi\|26107934, gi\|... - gi\|26247533\|ref\|NP_753573.1\| glutamyl-tRNA reductase [Escherichia coli CFT073], gi\|26107934\|gb\|AAN80... gi\|91072005, gi\|... - gi\|91210431\|ref\|YP_540417.1\| glutamyl-tRNA reductase [Escherichia coli UTI89], gi\|91072005\|gb\|ABE068...	360.0	[0..1]	[414..67]
gi\|110614763, gi... - gi\|110805215\|ref\|YP_688735.1\| glutamyl-tRNA reductase [Shigella flexneri 5 str. 8401], gi\|110614763\|... gi\|24112609, gi\|... - ref\|NP_707119.1\| glutamyl-tRNA reductase [Shigella flexneri 2a str. 301], gb\|AAN42826.1\| glutamyl-t...	359.0	[0..1]	[414..67]
HEM1_VIBPA - Glutamyl-tRNA reductase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=hemA PE=3... HEM1_VIBPA - Glutamyl-tRNA reductase OS=Vibrio parahaemolyticus GN=hemA PE=3 SV=1	358.0	[0..1]	[415..1]
gi\|205339555, gi... - gi\|205339555\|gb\|EDZ26319.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Hei... gi\|205350779, gi... - gi\|205350779\|gb\|EDZ37410.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Had... gi\|195634371, gi... - gi\|195634371\|gb\|EDX52723.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar New... gi\|205342650, gi... - gi\|205342650\|gb\|EDZ29414.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Wel... lcl\|NC_016856.1_... - [gene=hemA] [protein=glutamyl-tRNA reductase] [protein_id=YP_005237706.1] [location=complement(18851... gi\|205321990, gi... - gi\|205321990\|gb\|EDZ09829.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Sai... gi\|205328701, gi... - gi\|205328701\|gb\|EDZ15465.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar 4,[... gi\|205332114, gi... - gi\|205332114\|gb\|EDZ18878.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Ken... gi\|197289194, gi... - gi\|197289194\|gb\|EDY28561.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Sch... HEM1_SALTY - Glutamyl-tRNA reductase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=hemA PE=3... gi\|213426494 - gi\|213426494\|ref\|ZP_03359244.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... gi\|29137198, gi\|... - gi\|29141571\|ref\|NP_804913.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Ty... gi\|213583754 - gi\|213583754\|ref\|ZP_03365580.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... gi\|16760670 - gi\|16760670\|ref\|NP_456287.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar Ty... gi\|204322934, gi... - gi\|204927592\|ref\|ZP_03218793.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... HEM1_SALG2 - Glutamyl-tRNA reductase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=hemA PE=3 SV=1 HEM1_SALEP - Glutamyl-tRNA reductase OS=Salmonella enteritidis PT4 (strain P125109) GN=hemA PE=3 SV=1 gi\|213051787 - gi\|213051787\|ref\|ZP_03344665.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... HEM1_SALTY - Glutamyl-tRNA reductase OS=Salmonella typhimurium GN=hemA PE=3 SV=1 HEM1_SALA4 - Glutamyl-tRNA reductase OS=Salmonella agona (strain SL483) GN=hemA PE=3 SV=1 gi\|197241202, gi... - gi\|197262947\|ref\|ZP_03163021.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... HEM1_SALPK - Glutamyl-tRNA reductase OS=Salmonella paratyphi A (strain AKU_12601) GN=hemA PE=3 SV=1 gi\|199602893, gi... - gi\|200390448\|ref\|ZP_03217059.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... HEM1_SALNS - Glutamyl-tRNA reductase OS=Salmonella newport (strain SL254) GN=hemA PE=3 SV=1 gi\|238913677 - gi\|238913677\|ref\|ZP_04657514.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... HEM1_SALHS - Glutamyl-tRNA reductase OS=Salmonella heidelberg (strain SL476) GN=hemA PE=3 SV=1 gi\|194471470, gi... - gi\|194471470\|ref\|ZP_03077454.1\| glutamyl-tRNA reductase [Salmonella enterica subsp. enterica serovar... HEM1_SALSV - Glutamyl-tRNA reductase OS=Salmonella schwarzengrund (strain CVM19633) GN=hemA PE=3 SV=1 HEM1_SALPB - Glutamyl-tRNA reductase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=hemA PE=3 SV=1 HEM1_SALTY - Glutamyl-tRNA reductase OS=Salmonella typhimurium GN=hemA PE=3 SV=1 HEM1_SALTI - Glutamyl-tRNA reductase OS=Salmonella typhi GN=hemA PE=3 SV=1 HEM1_SALTI - Glutamyl-tRNA reductase OS=Salmonella typhi GN=hemA PE=3 SV=1 HEM1_SALPA - Glutamyl-tRNA reductase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=hemA PE=3 SV=1 HEM1_SALPB - Glutamyl-tRNA reductase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=hemA PE=3 SV=1 HEM1_SALPA - Glutamyl-tRNA reductase OS=Salmonella paratyphi A GN=hemA PE=3 SV=1 HEM1_SALAR - Glutamyl-tRNA reductase OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) GN=hemA P...	357.0	[0..1]	[414..1]
HEM1_SHESW - Glutamyl-tRNA reductase OS=Shewanella sp. (strain W3-18-1) GN=hemA PE=3 SV=1 HEM1_SHEPC - Glutamyl-tRNA reductase OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=hemA PE=3 SV=1	356.0	[0..1]	[416..1]
HEM1_SALCH - Glutamyl-tRNA reductase OS=Salmonella choleraesuis GN=hemA PE=3 SV=1 HEM1_SALCH - Glutamyl-tRNA reductase OS=Salmonella choleraesuis (strain SC-B67) GN=hemA PE=3 SV=1 HEM1_SALCH - Glutamyl-tRNA reductase OS=Salmonella choleraesuis GN=hemA PE=3 SV=1	356.0	[0..1]	[414..1]
gi\|154103 - gi\|154103\|gb\|AAA88610.1\| hemA gene product gi\|154103\|gb\|AAA... - hemA gene product	356.0	[0..1]	[414..1]
HEM1_VIBVY - Glutamyl-tRNA reductase OS=Vibrio vulnificus (strain YJ016) GN=hemA PE=3 SV=1	355.0	[0..1]	[415..1]
HEM1_SHEB2 - Glutamyl-tRNA reductase OS=Shewanella baltica (strain OS223) GN=hemA PE=3 SV=1 HEM1_SHEB5 - Glutamyl-tRNA reductase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=hemA PE=3 SV=1 HEM1_SHEB9 - Glutamyl-tRNA reductase OS=Shewanella baltica (strain OS195) GN=hemA PE=3 SV=1	355.0	[0..1]	[416..1]
gi\|1651600, gi\|8... - gi\|89108055\|ref\|AP_001835.1\| glutamyl tRNA reductase [Escherichia coli str. K-12 substr. W3110], gi\|... HEM1_ECOLI - Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR) - Escherichia coli gi\|13361180, gi\|... - gi\|15830969\|ref\|NP_309742.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. Sakai], gi\|13361... HEM1_ECOBW - Glutamyl-tRNA reductase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=hemA PE=3 SV=1 gi\|208737546, gi... - gi\|208822061\|ref\|ZP_03262380.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|254592080, gi... - gi\|254792680\|ref\|YP_003077517.1\| glutamyl tRNA reductase [Escherichia coli O157:H7 str. TW14359], gi... HEM1_ECO5E - Glutamyl-tRNA reductase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=hemA PE=3 SV=1 HEM1_ECO57 - Glutamyl-tRNA reductase OS=Escherichia coli O157:H7 GN=hemA PE=3 SV=1 gi\|217318469, gi... - gi\|217328042\|ref\|ZP_03444124.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. TW14588], gi\|... EG10427 - glutamyl tRNA reductase / Glutamyl-tRNA reductase, hemin biosynthesis; neomycin sensitivity HEM1_ECOLU - Glutamyl-tRNA reductase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=hemA PE=3 SV=1 gi\|188015100, gi... - gi\|188015100\|gb\|EDU53222.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4113], gi\|16875... gi\|168776897, gi... - gi\|187767799\|gb\|EDU31643.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|189000013, gi... - gi\|189000013\|gb\|EDU68999.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4076], gi\|16878... HEM1_ECODH - Glutamyl-tRNA reductase OS=Escherichia coli (strain K12 / DH10B) GN=hemA PE=3 SV=1 EG10427 - glutamyl tRNA reductase / Glutamyl-tRNA reductase, hemin biosynthesis; neomycin sensitivity gi\|193069944, gi... - gi\|75235278\|ref\|ZP_00719515.1\| COG0373: Glutamyl-tRNA reductase [Escherichia coli E110019], gi\|19306... gi\|195939098 - gi\|195939098\|ref\|ZP_03084480.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4024] gi\|208726581, gi... - gi\|208806780\|ref\|ZP_03249117.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4206], gi\|2... gi\|208814821, gi... - gi\|208814821\|ref\|ZP_03256000.1\| glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4045], gi\|2...	355.0	[0..1]	[414..1]

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Predicted Domain #1

Region A:
Residues: [1-416]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLVAIGINH KTATVDLREK VAFSPDKIHD AMKSLASRTR SGEAVIVSTC NRTELYCNNG  60
   61 DETDIIEWLE EYHGLEHQDV APCLYNYHGQ EAVRHLMRVA SGLDSLILGE PQILGQVKQA 120
  121 FVKAKEAGTV ALTIDRLFQN TFSVAKKVRT ETEIGAAAVS VAFAAVSMAK HIFSSLSTTK 180
  181 VLLIGAGETI ELVAKHLKDN GVASMVVANR TLERAQSMCE EFNATAITLA QIPDFLPKAD 240
  241 IVISSTASPL PILGKGMVEK ALKQRRHQPM LLVDIAVPRD IEPEVADLDD AFLYTVDDLH 300
  301 SIIEQNKASR KEAAEQAELI TEEQSHLFME WVRSLESVDS IREYRSQSMA IKDELVERAL 360
  361 NKLAQGGDTE QVLVELANRL TNRLIHAPTQ ALTVASRQGD LNTLGQLRTA LGLDKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.221849
Match:	1gpjA
Description:	Glutamyl tRNA-reductase dimerization domain; Glutamyl tRNA-reductase middle domain; Glutamyl tRNA-reductase catalytic, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity	0.881088609158401	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: