YRC Public Data Repository - Protein Structure Prediction

Protein:	CHEB1_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	374 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHEB1_SHEON.

Description	E-value	Query Range	Subject Range
CHEB_THICR - Chemotaxis response regulator protein-glutamate methylesterase OS=Thiomicrospira crunogena (strain X...	255.0	[0..1]	[373..1]
gi\|116216840, gi... - gi\|75823333\|ref\|ZP_00752842.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... tr\|D7HAB4\|D7HAB4... - Chemotaxis response regulator protein-glutamate methylesterase OS=Vibrio cholerae RC385 GN=cheB PE=3...	252.0	[0..1]	[372..1]
CHEB1_SHESR - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Shewanella sp. (strain MR-7) GN=...	250.0	[0..1]	[374..1]
SO2327 - protein-glutamate methylesterase CheB CHEB3_SHEON - Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon OS=Shewanella oneid...	248.0	[0..3]	[370..2]
CHEB_THIDA - Chemotaxis response regulator protein-glutamate methylesterase OS=Thiobacillus denitrificans (strain...	248.0	[0..1]	[372..1]
CHEB1_GEOMG - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Geobacter metallireducens (strai...	248.0	[0..2]	[367..5]
gi\|117919811, gi... - gi\|78686515\|ref\|ZP_00851281.1\| Protein-glutamate methylesterase [Shewanella sp. ANA-3], gi\|78505679\|...	248.0	[0..1]	[374..1]
CHEB1_PSEPK - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon OS=Pseudomonas puti...	248.0	[0..1]	[371..1]
tr\|E4RC32\|E4RC32... - Chemotaxis response regulator protein-glutamate methylesterase OS=Pseudomonas putida (strain BIRD-1)... gi\|148510827, gi... - gi\|82738756\|ref\|ZP_00901581.1\| Response regulator receiver [Pseudomonas putida F1], gi\|82714148\|gb\|E...	247.0	[0..1]	[371..1]
gi\|167347016, gi... - gi\|167644586\|ref\|YP_001682249.1\| response regulator receiver modulated CheB methylesterase [Caulobac...	247.0	[0..3]	[373..7]

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Predicted Domain #1

Region A:
Residues: [1-374]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIKVLVVDD SSFFRRRVSE IVNQDPELEV IATASNGAEA VKMTADLNPQ VITMDIEMPV  60
   61 MDGITAVREI MAKCPTPILM FSSLTHDGAK ATLDALDAGA LDFLPKRFED IATNKDEAIL 120
  121 LLQQRVKALG RRRIFRPITR PSVAPVTPRP TTGSAVGNAT TPVQSASAPV RSSPLSSIRA 180
  181 SGKQYKLLLI GTSTGGPVAL QKVLTQFPAN YPHPILLIQH MPAAFTPAFA SRLNGLCKIE 240
  241 VKEAANGDIL RPGCAYLAPG GMQMMVERAG VTGRIKVLAG SAEMNYKPCV DITFASASKA 300
  301 YGGDVLAVVL TGMGADGREG ARMLKAAGAT IWAQDEASCV VYGMPQAVAS TGIATQSISL 360
  361 DNMAESILKE SARG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.69897
Match:	1a2oA
Description:	Methylesterase CheB, N-terminal domain; Methylesterase CheB, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-glutamate methylesterase activity	4.76725156113043	bayes_pls_golite062009
protein methylesterase activity	4.76725156113043	bayes_pls_golite062009
carboxylesterase activity	2.33136193064185	bayes_pls_golite062009
two-component response regulator activity	2.03903098126833	bayes_pls_golite062009
catalytic activity	1.51345676907336	bayes_pls_golite062009
hydrolase activity	1.38910925240185	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.880545826023013	bayes_pls_golite062009
binding	0.774059954444038	bayes_pls_golite062009
nucleic acid binding	0.0928619295989472	bayes_pls_golite062009
DNA binding	0.0743796794876224	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: