YRC Public Data Repository - Protein Structure Prediction

Protein:	RIBA_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	203 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIBA_SHEON.

Description	E-value	Query Range	Subject Range
gi\|56420830, gi\|... - gi\|56420830\|ref\|YP_148148.1\| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohyd...	323.0	[0..3]	[195..205]
gi\|78219884, gi\|... - gi\|78357479\|ref\|YP_388928.1\| GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase [...	321.0	[0..1]	[203..205]
gi\|46579610, gi\|... - gi\|46579610\|ref\|YP_010418.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [De... gi\|241906910, gi... - gi\|241906910\|ref\|ZP_04791491.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Desulfovibrio vulgari... gi\|120602902, gi... - gi\|120602902\|ref\|YP_967302.1\| GTP cyclohydrolase II [Desulfovibrio vulgaris subsp. vulgaris DP4], gi...	318.0	[0..1]	[198..205]
gi\|28202834, gi\|... - gi\|28210397\|ref\|NP_781341.1\| riboflavin biosynthesis protein ribA [Clostridium tetani E88], gi\|28202...	318.0	[0..3]	[195..209]
gi\|78222835, gi\|... - gi\|78222835\|ref\|YP_384582.1\| GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase [...	315.0	[0..3]	[196..206]
gi\|77545131, gi\|... - gi\|77919048\|ref\|YP_356863.1\| putative bifunctional enzyme 3,4-dihydroxy-2-butanone 4-phosphate/GTP c...	315.0	[0..3]	[196..206]
gi\|22295453, gi\|... - gi\|22299270\|ref\|NP_682517.1\| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohyd...	315.0	[0..3]	[199..209]
gi\|39996790, gi\|... - gi\|39996790\|ref\|NP_952741.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Ge...	313.0	[0..3]	[196..206]
gi\|110547132, gi... - gi\|222055766\|ref\|YP_002538128.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Geobacter sp. FRC-32...	313.0	[0..3]	[196..206]
gi\|78189744, gi\|... - gi\|78189744\|ref\|YP_380082.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Chlorobium chlorochromat...	313.0	[0..3]	[194..209]

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Predicted Domain #1

Region A:
Residues: [1-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKYVATSK LPTPWGVFAM HGFEDTETGK EHVALTFGSL SSDEPVLGRI HSECLTGDAL  60
   61 FSLRCDCGFQ LQTAMQNIAE TGSGFILYLR QEGRGIGLLN KIRAYELQDK GANTVEANEQ 120
  121 LGFPADMRKY DMIQPMLEKI GVKHVRLMTN NPRKVKAMKE IGIEVVERVP LQVGKNRYNE 180
  181 AYLKTKSTEL GHMMSEYHFT DEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.0
Match:	2bz0A
Description:	Crystal Structure of E. coli GTP cyclohydrolase II in complex with GTP analogue, GMPcPP, and Zinc
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTP cyclohydrolase II activity	5.52815352448731	bayes_pls_golite062009
GTP cyclohydrolase activity	4.68330806755482	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4.17350205350813	bayes_pls_golite062009
cyclohydrolase activity	3.79278058687802	bayes_pls_golite062009
catalytic activity	1.77808031039581	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.336476611336042	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: