YRC Public Data Repository - Protein Structure Prediction

Protein:	FABH_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	319 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABH_SHEON.

Description	E-value	Query Range	Subject Range
FABH_CALS8 - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Caldicellulosiruptor saccharolyticus (strain ATCC 434...	316.0	[0..2]	[319..4]
FABH_CLOAB - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Clostridium acetobutylicum GN=fabH PE=3 SV=1 FABH_CLOAB - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792...	314.0	[0..1]	[319..1]
FABH_NITEU - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298... FABH_NITEU - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Nitrosomonas europaea GN=fabH PE=3 SV=1	309.0	[0..1]	[319..1]
FABH_NITEC - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Nitrosomonas eutropha (strain C91) GN=fabH PE=3 SV=1	308.0	[0..1]	[319..3]
FABH_MARHV - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Marinobacter hydrocarbonoclasticus (strain ATCC 70049...	297.0	[0..3]	[319..4]
FABH_METCA - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Methylococcus capsulatus GN=fabH PE=3 SV=1 FABH_METCA - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 1...	297.0	[0..2]	[319..4]
FABH_STAHJ - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Staphylococcus haemolyticus (strain JCSC1435) GN=fabH...	296.0	[0..1]	[319..1]
gi\|78363341, gi\|... - gi\|78485055\|ref\|YP_390980.1\| 3-oxoacyl-(acyl-carrier-protein) synthase III [Thiomicrospira crunogena...	296.0	[0..1]	[319..5]
FABH_ACIET - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Acidovorax ebreus (strain TPSY) GN=fabH PE=3 SV=1 FABH_ACISJ - 3-oxoacyl-[acyl-carrier-protein] synthase 3 OS=Acidovorax sp. (strain JS42) GN=fabH PE=3 SV=1	296.0	[0..2]	[318..4]
gi\|166856536, gi... - gi\|76797521\|ref\|ZP_00779827.1\| Beta-ketoacyl-acyl carrier protein synthase III (FabH) [Thermoanaerob...	296.0	[0..1]	[319..5]

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Predicted Domain #1

Region A:
Residues: [1-319]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTKILGTGS YVPVQVRSNQ DLEKMVETSD QWIVERTGIS ERRIAAQDET VSTMGYLAAL  60
   61 NALEMAGIEA SDLDMIICGT TSAANAFPAA ACEIQAMLGV HTIPAFDIAA ACSGFVYALS 120
  121 VADQFVKNGT AKKVLVIGAD VLSRLCEPED RTTIILFGDG AGAAIIGASD EPGIISTHIY 180
  181 ADGRQGDLLK CAFPPRQGET SEAVGFMTMK GNDVFKVAVT QLSHVVTETL RLNNIDKSEI 240
  241 DWLVPHQANF RIINATAKKL DMSLDKVVLT LAKHGNTSAA SVPIALDEAV RDGRIQRGQL 300
  301 LLLEAFGAGF AWGSALVRF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.39794
Match:	1hn9A
Description:	Ketoacyl-ACP synthase III (FabH)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fatty acid synthase activity	4.37139275892693	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] synthase activity	4.06397243593186	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.54029185395409	bayes_pls_golite062009
acyltransferase activity	3.43583434657402	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.19599732838453	bayes_pls_golite062009
catalytic activity	2.51549172199072	bayes_pls_golite062009
C-acyltransferase activity	2.3644638173834	bayes_pls_golite062009
acetyl-CoA C-acetyltransferase activity	1.78507287846874	bayes_pls_golite062009
transferase activity	1.65550781281407	bayes_pls_golite062009
C-acetyltransferase activity	1.51395085399712	bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity	0.794784660158621	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: