YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24348307, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	535 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24348307, gi|....

Description	E-value	Query Range	Subject Range
gi\|84690477, gi\|... - gi\|84704043\|ref\|ZP_01017871.1\| dihydrolipoamide acetyltransferase [Parvularcula bermudensis HTCC2503...	481.0	[0..2]	[534..1]
gi\|89068137, gi\|... - gi\|89068137\|ref\|ZP_01155554.1\| dihydrolipoamide acetyltransferase [Oceanicola granulosus HTCC2516], ...	477.0	[0..1]	[534..1]
gi\|77464544, gi\|... - gi\|77464544\|ref\|YP_354048.1\| dihydrolipoamide acetyltransferase [Rhodobacter sphaeroides 2.4.1], gi\|...	476.0	[0..1]	[534..2]
gi\|84667992, gi\|... - gi\|84684239\|ref\|ZP_01012141.1\| Dihydrolipoamide transsuccinylase [Rhodobacterales bacterium HTCC2654...	475.0	[0..1]	[534..1]
gi\|126105048, gi... - gi\|83372573\|ref\|ZP_00917353.1\| Dihydrolipoamide succinyltransferase [Rhodobacter sphaeroides ATCC 17...	473.0	[0..1]	[534..1]
gi\|254880079 - gi\|254880079\|ref\|ZP_05252789.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes FSL J2-07... gi\|254853059 - gi\|254853059\|ref\|ZP_05242407.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes FSL R2-50... gi\|46907286, gi\|... - gi\|46907286\|ref\|YP_013675.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes str. 4b F236... gi\|47018693, gi\|... - gi\|47092946\|ref\|ZP_00230727.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes str. 4b H7... gi\|153166389, gi... - gi\|153166389\|ref\|ZP_01926975.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes FSL N1-01... gi\|254933398, gi... - gi\|254933398\|ref\|ZP_05266757.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes HPB2262],... gi\|226223672, gi... - gi\|226223672\|ref\|YP_002757779.1\| pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subun...	473.0	[0..1]	[533..1]
gi\|224502632 - gi\|224502632\|ref\|ZP_03670939.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes FSL R2-56... gi\|16803094 - gi\|16803094\|ref\|NP_464579.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes EGD-e] gi\|16410456, gi\|... - pir\|\|AF1206 pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 chain) homolog pdhC [impor...	469.0	[0..1]	[533..1]
gi\|254898773, gi... - gi\|254898773\|ref\|ZP_05258697.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes J0161], g... gi\|127765847, gi... - gi\|254911738\|ref\|ZP_05261750.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes J2818], g... gi\|153195851, gi... - gi\|254830177\|ref\|ZP_05234832.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes 10403S], ... gi\|47096143, gi\|... - gi\|47096143\|ref\|ZP_00233743.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes str. 1/2a ... gi\|153179173, gi... - gi\|254936064\|ref\|ZP_05267761.1\| dihydrolipoamide acetyltransferase [Listeria monocytogenes F6900], g...	469.0	[0..1]	[533..1]
gi\|83361720, gi\|... - gi\|83368629\|ref\|ZP_00913491.1\| Dihydrolipoamide succinyltransferase [Rhodobacter sphaeroides ATCC 17...	469.0	[0..1]	[534..1]
gi\|114707322, gi... - gi\|114707322\|ref\|ZP_01440219.1\| dihydrolipoamide acetyltransferase [Fulvimarina pelagi HTCC2506], gi...	469.0	[0..1]	[534..1]

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Predicted Domain #1

Region A:
Residues: [1-90]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKDFILPDI GEGVVECELV EWLVKEGDTI VEDQPIADVM TDKALVQIPA PFAGVVTKLY  60
   61 YAKGDIAKVH APLYAVQIEA EEPSSQVAPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.69897
Match:	1labA
Description:	THREE-DIMENSIONAL STRUCTURE OF THE LIPOYL DOMAIN FROM BACILLUS STEAROTHERMOPHILUS PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dihydrolipoyllysine-residue acetyltransferase activity	7.74877411346968	bayes_pls_golite062009
S-acetyltransferase activity	7.59642806209362	bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity	7.45508609960612	bayes_pls_golite062009
pyruvate dehydrogenase activity	7.05950875585975	bayes_pls_golite062009
S-acyltransferase activity	5.24395351180663	bayes_pls_golite062009
acetyltransferase activity	3.55333192628786	bayes_pls_golite062009
acetyl-CoA carboxylase activity	3.31123635155865	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	2.83081843426182	bayes_pls_golite062009
CoA carboxylase activity	2.82233689048595	bayes_pls_golite062009
acyltransferase activity	2.79754636323803	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	2.53708026587542	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.22092493760605	bayes_pls_golite062009
catalytic activity	1.39099902011318	bayes_pls_golite062009
binding	0.988780943163898	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.629490807878017	bayes_pls_golite062009
ligase activity	0.56894584941056	bayes_pls_golite062009
aminomethyltransferase activity	0.377624262164477	bayes_pls_golite062009
protein binding	0.273657523907432	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	0.0222922933292004	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	0.0222922933292004	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [91-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVEHSAPNQA AISAASSSIE QFLLPDIGEG IVECELVEWL VQEGDIVVED QPIADVMTDK  60
   61 ALVQIPAIKA GKIVKLHYRK GQLAKVHAPL YAIEVEGGVI PAVSAHETTN VAVANTATSA 120
  121 ACATASVSQE PARQGKALAS PAVRRMARAL DIDLSRVPGS GKHGRVYKED ISRFQAQGSA 180
  181 TPVVAPVATA STQQSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.221849
Match:	1zy8K
Description:	The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [287-535]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTQSAVPITV ASAARADIVE PIRGVKAVMA KLMVESVSTI PHFTYCEEFD LTDLVALRES  60
   61 MKAKYSSDEV KLTMMPFFMK AMSLALTQFP VLNSQVNADC TEITYKARHN IGMAVDSKVG 120
  121 LLVPNVKDVQ DKSILEVAAE ITRLTNAARS GRVAPADLKE GTISISNIGA LGGTVATPII 180
  181 NKPEVAIVAL GKLQTLPRFN AKGEVEARQI MQVSWSGDHR VIDGGTIARF CNLWKQYLEQ 240
  241 PQDMLLAMR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.045757
Match:	2ihwA
Description:	No description for 2ihwA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: