YRC Public Data Repository - Protein Structure Prediction

Protein:	CHEB2_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	351 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHEB2_SHEON.

Description	E-value	Query Range	Subject Range
CHEB_METFK - Chemotaxis response regulator protein-glutamate methylesterase OS=Methylobacillus flagellatus (strai...	257.0	[0..1]	[347..1]
gi\|110547507, gi... - gi\|222056776\|ref\|YP_002539138.1\| response regulator receiver modulated CheB methylesterase [Geobacte...	253.0	[0..1]	[350..1]
CHEB_THIDA - Chemotaxis response regulator protein-glutamate methylesterase OS=Thiobacillus denitrificans (strain...	250.0	[0..1]	[350..1]
CHEB1_GEOMG - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Geobacter metallireducens (strai...	249.0	[0..3]	[349..6]
gi\|161361074 - gi\|161361074\|ref\|ZP_02106932.1\| chemotaxis-specific methylesterase [Burkholderia pseudomallei 1106b] gi\|167920937 - gi\|167920937\|ref\|ZP_02508028.1\| chemotaxis-specific methylesterase [Burkholderia pseudomallei BCC215... gi\|161372009 - gi\|161372009\|ref\|ZP_02111572.1\| chemotaxis-specific methylesterase [Burkholderia pseudomallei 1710a] gi\|194523323, gi... - gi\|254201439\|ref\|ZP_04907803.1\| protein-glutamate methylesterase CheB [Burkholderia mallei FMH], gi\|... CHEB1_BURPS - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Burkholderia pseudomallei GN=che... CHEB1_BURPS - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Burkholderia pseudomallei (strai...	245.0	[0..2]	[349..7]
gi\|242140518, gi... - gi\|82533688\|ref\|ZP_00892746.1\| hypothetical protein Bpse110_02005003 [Burkholderia pseudomallei 1106... gi\|237814241, gi... - gi\|237814241\|ref\|YP_002898692.1\| chemotaxis response regulator protein-glutamate methylesterase [Bur... gi\|83617620 - gi\|83617620\|ref\|ZP_00928115.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|225934913, gi... - gi\|226193313\|ref\|ZP_03788923.1\| protein-glutamate methylesterase CheB [Burkholderia pseudomallei Pak... gi\|126452993, gi... - gi\|82528071\|ref\|ZP_00887362.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|254174717, gi... - gi\|254174717\|ref\|ZP_04881378.1\| protein-glutamate methylesterase CheB [Burkholderia mallei ATCC 1039... gi\|217424088, gi... - gi\|217424088\|ref\|ZP_03455588.1\| protein-glutamate methylesterase CheB [Burkholderia pseudomallei 576... gi\|167740663 - gi\|167740663\|ref\|ZP_02413437.1\| chemotaxis-specific methylesterase [Burkholderia pseudomallei 14] gi\|167896347 - gi\|167896347\|ref\|ZP_02483749.1\| chemotaxis-specific methylesterase [Burkholderia pseudomallei 7894] gi\|124383457, gi... - gi\|124383457\|ref\|YP_001027669.1\| chemotaxis-specific methylesterase [Burkholderia mallei NCTC 10229]... CHEB1_BURMA - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Burkholderia mallei (strain ATCC... CHEB1_BURMA - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Burkholderia mallei GN=cheB1 PE=... gi\|85066013 - gi\|85066013\|ref\|ZP_01026866.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|194575939, gi... - gi\|87314844\|ref\|ZP_01095881.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|84520043, gi\|... - gi\|84520043\|ref\|ZP_01007181.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|67759142, gi\|... - gi\|67759142\|ref\|ZP_00497886.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|167002960, gi... - gi\|243061448\|gb\|EES43634.1\| protein-glutamate methylesterase CheB [Burkholderia mallei PRL-20], gi\|1... CHEB1_BURP1 - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Burkholderia pseudomallei (strai... gi\|67635111, gi\|... - gi\|67635111\|ref\|ZP_00434072.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|67639818, gi\|... - gi\|67639818\|ref\|ZP_00438651.1\| chemotaxis response regulator protein-glutamate methylesterase [Burkh... gi\|254206781, gi... - gi\|83622736\|ref\|ZP_00933035.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|254298795, gi... - gi\|83676003\|ref\|ZP_00937807.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|126440387, gi... - gi\|67738617\|ref\|ZP_00489258.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|194512505, gi... - gi\|67752176\|ref\|ZP_00491182.1\| COG2201: Chemotaxis response regulator containing a CheY-like receive... gi\|184214416, gi... - gi\|99908412\|ref\|ZP_01316116.1\| hypothetical protein Bpse1_03004572 [Burkholderia pseudomallei 1655],... gi\|90290290, gi\|... - gi\|90290290\|ref\|ZP_01209956.1\| hypothetical protein Bpse17_02005032 [Burkholderia pseudomallei 1710a...	245.0	[0..2]	[349..4]
CHEB1_BURTA - Chemotaxis response regulator protein-glutamate methylesterase 1 OS=Burkholderia thailandensis (stra... gi\|167620822 - gi\|167620822\|ref\|ZP_02389453.1\| chemotaxis-specific methylesterase [Burkholderia thailandensis Bt4]	245.0	[0..2]	[349..4]
gi\|67155749, gi\|... - gi\|67155749\|ref\|ZP_00417376.1\| Protein-glutamate methylesterase [Azotobacter vinelandii AvOP], gi\|67... gi\|67155749, gi\|... - gi\|67155749\|ref\|ZP_00417376.1\| Protein-glutamate methylesterase [Azotobacter vinelandii AvOP], ref\|Z...	244.0	[0..2]	[350..15]
CHEB3_LEPIC - Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon OS=Leptospira inter... CHEB3_LEPIN - Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon OS=Leptospira inter... CHEB3_LEPIN, CHB... - Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon OS=Leptospira inter... CHB3_LEPIC, CHEB... - Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon OS=Leptospira inter...	244.0	[0..2]	[341..1]
gi\|91204342 - gi\|91204342\|emb\|CAJ71995.1\| strongly similar to chemotaxis response regulator protein (glutamate met...	243.0	[0..2]	[346..4]

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Predicted Domain #1

Region A:
Residues: [1-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIKVLVVDD STLIRSLLGK MIESDPELSL VGMAADAYMA KDMVNQFRPD VITLDIEMPK  60
   61 VDGLTFLDRL MKARPTAVVM ISALTEEGAD ATFNALALGA VDFIPKPKLD SPQGFNEYQD 120
  121 LILEKIKSAA KAKLLKALPS ASTPVKSSIK PALSQRTVNT QLVAIGASTG GTEAILALLK 180
  181 QFPAVMPPIV ITQHMPAGFT CTFADRLNKL TRFNVKQAEE GERLLPCYAY VAPGDQHLEI 240
  241 IKVGGSFKAK LSQGDKVSGH RPSVDVLFHS VAQYAGENAT AVILTGMGKD GADGIEAIDM 300
  301 QGGKTFAQGE QSCVVFGMPK EAIKRGAIHH VVELPQLGDK LLQYLASVNR D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.69897
Match:	1a2oA
Description:	Methylesterase CheB, N-terminal domain; Methylesterase CheB, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-glutamate methylesterase activity	4.76725156113043	bayes_pls_golite062009
protein methylesterase activity	4.76725156113043	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
carboxylesterase activity	2.33136193064185	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
hydrolase activity	1.38910925240185	bayes_pls_golite062009
two-component response regulator activity	1.36590668894754	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009
DNA binding	1.11037597107903	bayes_pls_golite062009
nucleic acid binding	0.93151849951839	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.880545826023013	bayes_pls_golite062009
transcription factor activity	0.62886970109503	bayes_pls_golite062009
catalytic activity	0.389119219295877	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: