YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24373658, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	567 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24373658, gi|....

Description	E-value	Query Range	Subject Range
MBHL_BRADU - Uptake hydrogenase large subunit OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NB... MBHL_BRAJA - Uptake hydrogenase large subunit OS=Bradyrhizobium japonicum GN=hupB PE=3 SV=1	619.0	[0..3]	[562..16]
gi\|95244, gi\|48722 - pir\|\|S11969 hydrogenase (EC 1.18.99.1) (uptake) large chain - Rhizobium leguminosarum, gi\|48722\|emb\|...	618.0	[0..3]	[562..16]
MBHL_RHILV - Uptake hydrogenase large subunit OS=Rhizobium leguminosarum bv. viciae GN=hupB PE=3 SV=1 gi\|536799 - gi\|536799\|emb\|CAA85431.1\| HUPL [Rhizobium leguminosarum]	617.0	[0..3]	[562..16]
gi\|90425255, gi\|... - gi\|90425255\|ref\|YP_533625.1\| nickel-dependent hydrogenase, large subunit [Rhodopseudomonas palustris...	614.0	[0..3]	[562..17]
gi\|77701268, gi\|... - gi\|77738800\|ref\|ZP_00807293.1\| IMP dehydrogenase/GMP reductase:Nickel-dependent hydrogenase, large s...	612.0	[0..3]	[562..17]
gi\|91975643, gi\|... - gi\|91975643\|ref\|YP_568302.1\| nickel-dependent hydrogenase, large subunit [Rhodopseudomonas palustris...	611.0	[0..3]	[562..17]
gi\|83376047 - gi\|83376047\|gb\|ABC17828.1\| HupL [Bradyrhizobium sp. UPM1029]	609.0	[0..3]	[562..16]
gi\|78693505, gi\|... - gi\|78693505\|ref\|ZP_00858019.1\| hydrogenase large chain [Bradyrhizobium sp. BTAi1], gi\|78519060\|gb\|EA...	606.0	[0..3]	[562..16]
hupL - hupL hydrogenase large chain 1065304:1067097 forward MW:65672	606.0	[0..3]	[563..17]
gi\|126462908, gi... - gi\|83373096\|ref\|ZP_00917875.1\| nickel-iron hydrogenase, large subunit [Rhodobacter sphaeroides ATCC ... gi\|221639927, gi... - gi\|221639927\|ref\|YP_002526189.1\| Uptake hydrogenase [Rhodobacter sphaeroides KD131], gi\|221160708\|gb... gi\|77388482, gi\|... - gi\|77464064\|ref\|YP_353568.1\| hydrogenase protein large subunit [Rhodobacter sphaeroides 2.4.1], gi\|7...	604.0	[0..3]	[562..15]

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Predicted Domain #1

Region A:
Residues: [1-567]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRVVIDPI TRIEGHLRIE VEVDENNVIN KAWSSSTLWR GIEVILKGRT PMDVGLIVQR  60
   61 ICGVCTYSHY RCGTEAVENA LGIQIPLNAK YLRSLMLTSL FMHDHIVHFY HLHGLDWVDV 120
  121 VSALSADPAK AAQIALKYTD KPIAAGEGEL RAVQERVKGF VETGKLGPFA NAYWGNGTYK 180
  181 FTPEQNLIAL SHYLKALEVQ RVAAEMLAIF GGKSPHPQSL VVGGVTSVRD MLSPARLQEW 240
  241 KQKHEIVTDF ILRAYQADIV MAAEAFGTEP SVLGGVNVKN FMATNDFVLA NGEYLFDQGV 300
  301 IMNGDLAGVS DINPDLIAED VSHAWYNADA PQHPYDGTTI PNYTGFVERD TVYGKLPTLD 360
  361 GDGKYSWVKS PRYQGEPVEV GPLSCLLVSY ARGNKVVVDA VNALLARTGL PVEALFTTLG 420
  421 RTAARMLQTV IVAQEGLKTF DALLTNIQSD ETTYVKPHID PSKEYVGHAM MEAPRGMLSH 480
  481 WIRIKNGVIE NYQAVVPTTW NAGPVDANGK IGPYEASLIG LKLEDPTKPL EVIRIIHSFD 540
  541 PCMACSVHVM DFKGQALSEF RVSPNGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	151.0
Match:	1h2aL
Description:	Nickel-iron hydrogenase, large subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ferredoxin hydrogenase activity	3.63852106070173	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	3.63852106070173	bayes_pls_golite062009
oxidoreductase activity, acting on hydrogen as donor	3.45611813853803	bayes_pls_golite062009
NADH dehydrogenase activity	3.2672032605265	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	2.70075876201392	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	2.4952454159327	bayes_pls_golite062009
oxidoreductase activity, acting on iron-sulfur proteins as donors	2.45015987642707	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.19558031681108	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	2.05566803830683	bayes_pls_golite062009
oxidoreductase activity	1.80355547790706	bayes_pls_golite062009
catalytic activity	1.13542026154948	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: