YRC Public Data Repository - Protein Structure Prediction

Protein:	HISX_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	438 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HISX_SHEON.

Description	E-value	Query Range	Subject Range
gi\|90411638, gi\|... - gi\|90411638\|ref\|ZP_01219648.1\| histidinol dehydrogenase [Photobacterium profundum 3TCK], gi\|90327528...	631.0	[0..1]	[437..1]
gi\|91226030, gi\|... - gi\|91226030\|ref\|ZP_01260957.1\| histidinol dehydrogenase [Vibrio alginolyticus 12G01], gi\|91189471\|gb...	629.0	[0..1]	[436..1]
gi\|194538746, gi... - gi\|75854240\|ref\|ZP_00761946.1\| COG0141: Histidinol dehydrogenase [Vibrio sp. Ex25], gi\|254230163\|ref...	628.0	[0..1]	[436..1]
tr\|D7H7Y1\|D7H7Y1... - Histidinol dehydrogenase OS=Vibrio cholerae RC385 GN=hisD PE=3 SV=1 gi\|116216696, gi... - gi\|75823481\|ref\|ZP_00752979.1\| COG0141: Histidinol dehydrogenase [Vibrio cholerae RC385], gi\|2542236...	627.0	[0..1]	[437..1]
HISX_PHOPR - Histidinol dehydrogenase OS=Photobacterium profundum (strain SS9) GN=hisD PE=3 SV=1 HISX_PHOPR - Histidinol dehydrogenase OS=Photobacterium profundum GN=hisD PE=3 SV=1	627.0	[0..1]	[437..1]
HISX_VIBVU - Histidinol dehydrogenase OS=Vibrio vulnificus (strain CMCP6) GN=hisD PE=3 SV=1 HISX_VIBVU - Histidinol dehydrogenase OS=Vibrio vulnificus GN=hisD PE=3 SV=1	625.0	[0..1]	[436..1]
HISX_VIBF1 - Histidinol dehydrogenase OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=hisD PE=3 SV=1	625.0	[0..1]	[436..1]
gi\|75819716, gi\|... - gi\|75819716\|ref\|ZP_00749784.1\| COG0141: Histidinol dehydrogenase [Vibrio cholerae V51], gi\|254225523... gi\|124115457, gi... - gi\|153214208\|ref\|ZP_01949243.1\| histidinol dehydrogenase [Vibrio cholerae 1587], gi\|124115457\|gb\|EAY...	625.0	[0..1]	[437..1]
HISX_VIBVY - Histidinol dehydrogenase OS=Vibrio vulnificus (strain YJ016) GN=hisD PE=3 SV=1	624.0	[0..1]	[436..1]
HISX_VIBCH - Histidinol dehydrogenase OS=Vibrio cholerae GN=hisD PE=3 SV=2 gi\|229608291, gi... - gi\|229608291\|ref\|YP_002878939.1\| histidinol dehydrogenase [Vibrio cholerae MJ-1236], gi\|229370946\|gb... gi\|229518178, gi... - gi\|229518178\|ref\|ZP_04407622.1\| histidinol dehydrogenase [Vibrio cholerae RC9], gi\|229344893\|gb\|EEO0... HISX_VIBCH - Histidinol dehydrogenase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN... gi\|229515516, gi... - gi\|229515516\|ref\|ZP_04404975.1\| histidinol dehydrogenase [Vibrio cholerae TMA 21], gi\|229347285\|gb\|E... gi\|229505272, gi... - gi\|229505272\|ref\|ZP_04394782.1\| histidinol dehydrogenase [Vibrio cholerae BX 330286], gi\|229357495\|g... gi\|227081306, gi... - gi\|227081306\|ref\|YP_002809857.1\| histidinol dehydrogenase [Vibrio cholerae M66-2], gi\|227009194\|gb\|A... gi\|121587429, gi... - gi\|121587429\|ref\|ZP_01677198.1\| histidinol dehydrogenase [Vibrio cholerae 2740-80], gi\|121548349\|gb\|... gi\|153222284, gi... - gi\|153222284\|ref\|ZP_01953044.1\| histidinol dehydrogenase [Vibrio cholerae MAK 757], gi\|124119026\|gb\|... gi\|153816898, gi... - gi\|153816898\|ref\|ZP_01969565.1\| histidinol dehydrogenase [Vibrio cholerae NCTC 8457], gi\|126512485\|g... gi\|229511058, gi... - gi\|229511058\|ref\|ZP_04400537.1\| histidinol dehydrogenase [Vibrio cholerae B33], gi\|229351023\|gb\|EEO1... gi\|121631228, gi... - gi\|75817336\|ref\|ZP_00747788.1\| COG0141: Histidinol dehydrogenase [Vibrio cholerae V52], gi\|121726282... gi\|75830138, gi\|... - gi\|75830138\|ref\|ZP_00759422.1\| COG0141: Histidinol dehydrogenase [Vibrio cholerae MO10], gi\|25484826...	623.0	[0..1]	[437..1]

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Predicted Domain #1

Region A:
Residues: [1-438]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMLTWAALS ADEQKTALQR SPLIGDSGLE QSVRAIVDAV ASRGDAAIKE FNQKFDGARL  60
   61 ANISSANSDN LRLSEHEIEA ASARVSPELK AAIAQAMANI DVFHSAQQFR PIDIETQAGV 120
  121 RCELRSEPIE KVGLYIPGGS APLISTVLML ALPATIAGCE QRVLVSPPPI NDAIVYAANV 180
  181 CGITEIYQVG GAQAIAALAF GTETIPSVDK IFGPGNRYVT EAKRLVSQDG RCTVSIDMPA 240
  241 GPSEVLVIAD SDANAQFIAA DLLSQAEHGP DSQVILVTDS LPLAQAVNQA LKSQLAALPR 300
  301 QEIAATALKG SRTILVKDMQ EAALVSNRYG PEHLIIQTRF PREVLNNIRA AGSVFLGAYT 360
  361 PESVGDYASG TNHVLPTYGY SRAVSSLSLA DFSRRFTVQE LSAKGLLGLG QAVMTLASNE 420
  421 LLDAHKNAVA VRLASLKG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	173.0
Match:	1k75A
Description:	L-histidinol dehydrogenase HisD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.80804701752928	bayes_pls_golite062009
histidinol dehydrogenase activity	2.32012109012499	bayes_pls_golite062009
oxidoreductase activity	2.31275077585879	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.24875477727877	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2.22720948878196	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: