YRC Public Data Repository - Protein Structure Prediction

Protein:	LPXB_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	385 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LPXB_SHEON.

Description	E-value	Query Range	Subject Range
gi\|145272457, gi... - gi\|145638128\|ref\|ZP_01793738.1\| lipid-A-disaccharide synthase [Haemophilus influenzae PittII], gi\|14... gi\|46133260 - gi\|46133260\|ref\|ZP_00156903.2\| COG0763: Lipid A disaccharide synthetase [Haemophilus influenzae R286...	246.0	[0..2]	[383..1]
LPXB_SHEFN - Lipid-A-disaccharide synthase OS=Shewanella frigidimarina (strain NCIMB 400) GN=lpxB PE=3 SV=1	245.0	[0..1]	[380..1]
gi\|120325295, gi... - gi\|77952648\|ref\|ZP_00817062.1\| Glycosyl transferase, family 19 [Marinobacter aquaeolei VT8], gi\|7786...	243.0	[0..9]	[382..16]
LPXB_HAEIN - Lipid-A-disaccharide synthase OS=Haemophilus influenzae GN=lpxB PE=3 SV=2 LPXB_HAEIN - Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) ...	243.0	[0..2]	[383..1]
gi\|1694783 - gi\|1694783\|emb\|CAA60866.1\| lpxB [Haemophilus influenzae]	243.0	[0..2]	[383..1]
gi\|46129048 - gi\|46129048\|ref\|ZP_00155774.2\| COG0763: Lipid A disaccharide synthetase [Haemophilus influenzae R284...	240.0	[0..2]	[381..1]
LPXB_SHESR - Lipid-A-disaccharide synthase OS=Shewanella sp. (strain MR-7) GN=lpxB PE=3 SV=1	240.0	[0..1]	[385..1]
LPXB_HAEI8 - Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain 86-028NP) GN=lpxB PE=3 SV=1	240.0	[0..2]	[381..1]
LPXB_SHESA - Lipid-A-disaccharide synthase OS=Shewanella sp. (strain ANA-3) GN=lpxB PE=3 SV=1	240.0	[0..1]	[385..1]

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Predicted Domain #1

Region A:
Residues: [1-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKSQLVFA MVAGELSGDI LGAGLMAALQ KTHPNARFVG IGGPRMEALG FESLFAMEEL  60
   61 AVMGIVEVLS RLPRLLHVRA SLIKSITELK PDCFIGIDAP DFNIGLELKL KAQGIKTVHY 120
  121 VSPSVWAWRP KRIFKIAKAT NMVLSLLPFE KAFYDKHQVP CTFVGHTLAD DIPLESDKAC 180
  181 ARQVLELDQE AEYLAILPGS RGGELKQLAE PFVKAALLIK QQFPDIRFVT PLVNQKRREQ 240
  241 FEQALKDHAP DLEIHMVEGK SREVMAAADG ILLASGTATL EAMLIKRPMV VAYRVSPLTY 300
  301 SIAKRMMQVN RFSLPNLLAG CDVVPELIQH DCTPEKIAAA VGVELNRDFA PIKAEFERLH 360
  361 QVLRCDASQK AAEAVLALVD FKEVN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.69897
Match:	1vgvA
Description:	Crystal structure of UDP-N-acetylglucosamine_2 epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring hexosyl groups	3.04530122157712	bayes_pls_golite062009
catalytic activity	3.02192459767177	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.94500176353224	bayes_pls_golite062009
glycogen phosphorylase activity	2.09116455393465	bayes_pls_golite062009
lipopolysaccharide heptosyltransferase activity	2.03374890992046	bayes_pls_golite062009
glucosyltransferase activity	1.8062586862583	bayes_pls_golite062009
transferase activity	1.67770954408305	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	1.63103907245982	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.4199532885636	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.30934991061674	bayes_pls_golite062009
glycogen (starch) synthase activity	0.435616523537281	bayes_pls_golite062009
phosphorylase activity	0.431662083250969	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.27693350081385	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.22009679964126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: