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View Structure Prediction Details

Protein: gi|24346905, gi|...
Organism: Shewanella oneidensis MR-1
Length: 1025 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24346905, gi|....

Description E-value Query
Range
Subject
Range
gi|116185291, gi... - gi|75855946|ref|ZP_00763584.1| COG0642: Signal transduction histidine kinase [Vibrio sp. Ex25], gi|2...
431.0 [0..4] [1023..1]
gi|117611834, gi... - gi|78685756|ref|ZP_00850531.1| Response regulator receiver:ATP-binding region, ATPase-like:Histidine...
428.0 [0..1] [1023..1]
gi|91188319, gi|... - gi|91227910|ref|ZP_01262049.1| sensor protein TorS [Vibrio alginolyticus 12G01], gi|91188319|gb|EAS7...
426.0 [0..4] [1023..1]
gi|54308425, gi|... - gi|54308425|ref|YP_129445.1| putative sensor protein TorS [Photobacterium profundum SS9], gi|4691285...
426.0 [0..4] [1024..1]
gi|114046620, gi... - gi|78691224|ref|ZP_00855850.1| Response regulator receiver:ATP-binding region, ATPase-like:Histidine...
424.0 [0..1] [1023..1]
gi|113884077, gi... - gi|82497967|ref|ZP_00883487.1| Response regulator receiver:ATP-binding region, ATPase-like:Histidine...
424.0 [0..1] [1022..1]
gi|28808910, gi|... - gi|28900530|ref|NP_800185.1| sensor protein TorS [Vibrio parahaemolyticus RIMD 2210633], gi|28808910...
gi|28808910 - gi|28808910|dbj|BAC62018.1| sensor protein TorS [Vibrio parahaemolyticus RIMD 2210633]
417.0 [0..4] [1023..1]
gi|90413299, gi|... - gi|90413299|ref|ZP_01221293.1| Hypothetical sensor protein TorS [Photobacterium profundum 3TCK], gi|...
416.0 [0..4] [1018..1]
gi|160876460, gi... - gi|160876460|ref|YP_001555776.1| multi-sensor hybrid histidine kinase [Shewanella baltica OS195], gi...
412.0 [0..1] [1022..1]
gi|90970717, gi|... - gi|90970717|gb|EAL68114.2| histidine kinase [Dictyostelium discoideum AX4], gi|111226686|ref|XP_6420...
DHKJ_DICDI - Hybrid signal transduction histidine kinase J OS=Dictyostelium discoideum GN=dhkJ PE=3 SV=2
408.0 [0..30] [1021..885]

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Predicted Domain #1
Region A:
Residues: [1-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPLSLSRRS LTGRLMLAFS VLGLLLLLLV SLGSLSLHWL KQADRYLYEE SLPASQAARQ  60
   61 LVQASNALSD GVTQLGQVED ERQREFIGRK LNLESATMLN SIKVLLALDV NEDNHLPVLA 120
  121 GQIIEQLTLL GQSVGQRITL GDELQRRARE LSVAAAHASE LLQSELAVVD SAILAKLSQA 180
  181 YPDMAGNKRS GQLLDDVIER ELDIQEQLNR ALKLVHQIAL LSQLFEVSEL QSELQLSVPR 240
  241 LLATFASTLP SHPVAHINQQ KGTAIEQASE AVTELSAPEV GIDLMALTTV SELIRDP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [298-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRLNALKAEL VTLKHTPKII KLQRDLSQSL QRQQRQQQAL AEKLYSLNTL VDSALNQQQQ  60
   61 RAELARSDYL MQLSYARFGL LATGMLMFVI MGWVIYRVIY RGIALRLNQA TQAMSRLSLG 120
  121 DINVSLDARG DDELTAMANA IEAFKRKTAH NLKLQADLRQ VADELTEHKK ALEQTVATRT 180
  181 QE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.33
Match: 2f95B
Description: M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [480-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAETNLRLDA EAKGHAKARV VAEEASQAKS QFLATMSHEI RTPLNGLLGT LTLLGQSQLP  60
   61 PAQQQMLALS QYSGTLLQTV LSDILDFSRL EQGNLTNEPR PTDINALLDE VLAIMVAGAN 120
  121 LAGLSLRLNR PQLPACINID GPKLRQVLFN LIGNGIKFTS EGSVSLNVSL QGGRLAFVVA 180
  181 DTGVGIAPEV REQLFIPYST LPNQGRSRGT GLGLAICKQL VELMDANGRG IWVKSEPGKG 240
  241 SEFGFELCFT Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [731-1025]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDKAQDAQTL VHKQVHTQRV LVVEDNKVNA MVAQGFLAHL GHSSTLAASC QLALECVSAD  60
   61 KAFDAVMLDI QLSDGSGVAL LPQLKALFGA KNVKFAAFTA QMQMEDLSLY REVGFDTVLA 120
  121 KPLSLQTLTQ WLGVAMASSS LETESPGLSA SPSFISASSA PLAQATDTSG AIPLGNQATE 180
  181 TLLDIEQLQQ DIEVLGVKAV SDMLALYKTS SAEQIERLSE ATFVESSADS AKLLHALKGS 240
  241 SASMGLKALT QCCQVWEKQL KTTGAQKLEI QSANELRACW LASMTALEQW LVTVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.69897
Match: 1ny5A
Description: Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
two-component response regulator activity 7.02872640261738 bayes_pls_golite062009
signal transducer activity 4.51666042720644 bayes_pls_golite062009
molecular transducer activity 4.51666042720644 bayes_pls_golite062009
transcription regulator activity 3.44888100104099 bayes_pls_golite062009
protein histidine kinase activity 2.35011582062573 bayes_pls_golite062009
two-component sensor activity 2.32303301074957 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.28838869071567 bayes_pls_golite062009
binding 1.22427537074115 bayes_pls_golite062009
DNA binding 1.11037597107903 bayes_pls_golite062009
nucleic acid binding 0.93151849951839 bayes_pls_golite062009
transcription factor activity 0.62886970109503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle