YRC Public Data Repository - Protein Structure Prediction

Protein:	LIPA_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	321 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIPA_SHEON.

Description	E-value	Query Range	Subject Range
gi\|167422569, gi... - gi\|167422569\|ref\|ZP_02314322.1\| lipoic acid synthetase [Yersinia pestis biovar Orientalis str. MG05-... gi\|167057867, gi... - gi\|167423697\|ref\|ZP_02315450.1\| lipoic acid synthetase [Yersinia pestis biovar Mediaevalis str. K197... gi\|167470781 - gi\|167470781\|ref\|ZP_02335485.1\| lipoic acid synthetase [Yersinia pestis FV-1] LIPA_YERPY - Lipoyl synthase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=lipA PE=3 SV=1 LIPA_YERPB - Lipoyl synthase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=lipA PE=3 SV=1 gi\|165937740, gi... - gi\|89102289\|ref\|ZP_01174934.1\| COG0320: Lipoate synthase [Yersinia pestis biovar Orientalis str. IP2... gi\|229898745, gi... - gi\|229898745\|ref\|ZP_04513890.1\| lipoate synthase [Yersinia pestis biovar Orientalis str. India 195],... LIPA_YERPA - Lipoyl synthase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=lipA PE=3 SV=1 gi\|229895935, gi... - gi\|229895935\|ref\|ZP_04511105.1\| lipoate synthase [Yersinia pestis Pestoides A], gi\|229700858\|gb\|EEO8... gi\|229694510, gi... - gi\|229838144\|ref\|ZP_04458303.1\| lipoate synthase [Yersinia pestis biovar Orientalis str. PEXU2], gi\|... gi\|165922979, gi... - gi\|165925372\|ref\|ZP_02221204.1\| lipoic acid synthetase [Yersinia pestis biovar Orientalis str. F1991... gi\|166008051, gi... - gi\|166008051\|ref\|ZP_02228949.1\| lipoic acid synthetase [Yersinia pestis biovar Antiqua str. E1979001... LIPA_YERPE - Lipoyl synthase OS=Yersinia pestis GN=lipA PE=3 SV=1 gi\|166212564, gi... - gi\|166212564\|ref\|ZP_02238599.1\| lipoic acid synthetase [Yersinia pestis biovar Antiqua str. B4200300... LIPA_YERPN - Lipoyl synthase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=lipA PE=3 SV=1 LIPA_YERPG - Lipoyl synthase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=lipA PE=3 SV=1 LIPA_YERPS - Lipoyl synthase OS=Yersinia pseudotuberculosis GN=lipA PE=3 SV=1 LIPA_YERP3 - Lipoyl synthase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=lipA PE=3 SV=1 LIPA_YERPS - Lipoyl synthase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=lipA PE=3 SV=1 gi\|149291914, gi... - gi\|149365501\|ref\|ZP_01887536.1\| lipoic acid synthetase [Yersinia pestis CA88-4125], gi\|149291914\|gb\|... gi\|22125074, gi\|... - gi\|22125074\|ref\|NP_668497.1\| lipoyl synthase [Yersinia pestis KIM], gi\|21957927\|gb\|AAM84748.1\|AE0137... gi\|15980585, gi\|... - gi\|218929679\|ref\|YP_002347554.1\| lipoyl synthase [Yersinia pestis CO92], gi\|16122811\|ref\|NP_406124.1... LIPA_YERPP - Lipoyl synthase OS=Yersinia pestis (strain Pestoides F) GN=lipA PE=3 SV=1	315.0	[0..1]	[321..1]
gi\|47573861 - gi\|47573861\|ref\|ZP_00243898.1\| COG0320: Lipoate synthase [Rubrivivax gelatinosus PM1] gi\|124265509, gi... - gi\|124265509\|ref\|YP_001019513.1\| lipoyl synthase [Methylibium petroleiphilum PM1], gi\|124258284\|gb\|A...	315.0	[0..7]	[320..24]
LIPA_SHELP - Lipoyl synthase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=lipA PE=3 SV=1	314.0	[0..1]	[321..1]
LIPA_SHEAM - Lipoyl synthase OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=lipA PE=3 SV=1	314.0	[0..1]	[321..1]
LIPA_VIBVY - Lipoyl synthase OS=Vibrio vulnificus (strain YJ016) GN=lipA PE=3 SV=1 LIPA_VIBVU - Lipoyl synthase OS=Vibrio vulnificus GN=lipA PE=3 SV=1 LIPA_VIBVU - Lipoyl synthase OS=Vibrio vulnificus (strain CMCP6) GN=lipA PE=3 SV=1	314.0	[0..1]	[321..1]
LIPA_VIBPA - Lipoyl synthase OS=Vibrio parahaemolyticus GN=lipA PE=3 SV=1 LIPA_VIBPA - Lipoyl synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=lipA PE=3 SV=1	312.0	[0..1]	[321..1]
LIPA_SHEB5 - Lipoyl synthase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=lipA PE=3 SV=1 LIPA_SHEB2 - Lipoyl synthase OS=Shewanella baltica (strain OS223) GN=lipA PE=3 SV=1 LIPA_SHEB9 - Lipoyl synthase OS=Shewanella baltica (strain OS195) GN=lipA PE=3 SV=1	312.0	[0..1]	[321..1]
LIPA_SHESW - Lipoyl synthase OS=Shewanella sp. (strain W3-18-1) GN=lipA PE=3 SV=1 LIPA_SHEPC - Lipoyl synthase OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=lipA PE=3 SV=1 gi\|124546234, gi... - gi\|124546234\|ref\|ZP_01705339.1\| lipoic acid synthetase [Shewanella putrefaciens 200], gi\|124510186\|g...	311.0	[0..1]	[321..1]
gi\|145639685, gi... - gi\|145639685\|ref\|ZP_01795288.1\| lipoyl synthase [Haemophilus influenzae PittII], gi\|145271242\|gb\|EDK... LIPA_HAEIN - Lipoyl synthase OS=Haemophilus influenzae GN=lipA PE=3 SV=1 gi\|145630682 - gi\|145630682\|ref\|ZP_01786461.1\| lipoyl synthase [Haemophilus influenzae 22.4-21] gi\|46133660 - gi\|46133660\|ref\|ZP_00157533.2\| COG0320: Lipoate synthase [Haemophilus influenzae R2866] LIPA_HAEIN - Lipoyl synthase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=lipA PE=3 S... gi\|144983808 - gi\|144983808\|gb\|EDJ91258.1\| lipoyl synthase [Haemophilus influenzae R3021]	311.0	[0..1]	[321..1]

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Predicted Domain #1

Region A:
Residues: [1-321]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRPERLQPG VKLRDAEKVS RIPVKIVPSE RETMLRKPDW LRVKLPASNQ RILDIKQALR  60
   61 ANGLHSVCEE ASCPNLAECF NHGTATFMIL GAICTRRCPF CDVAHGRPLK PDEQEPVKLA 120
  121 QTIRDMKLKY VVITSVDRDD LRDGGAQHFA DCIREIRKLN PEIKIEILVP DFRGRIDAAL 180
  181 DILSTEPPDV FNHNLETAPM HYRKARPGAN YQWSLDLLKR FKERHPNVPT KSGLMMGLGE 240
  241 TNDEIAQVLR DLREHKVEML TLGQYLQPSK FHLPVERYVS PAEFDELKAL ADELGFTHAA 300
  301 CGPLVRSSYH ADLQAQGKEV K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1r30A
Description:	The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
biotin synthase activity	2.22585029668171	bayes_pls_golite062009
radical SAM enzyme activity	2.08127882819276	bayes_pls_golite062009
catalytic activity	1.85375915825216	bayes_pls_golite062009
coproporphyrinogen oxidase activity	1.27516985221578	bayes_pls_golite062009
sulfurtransferase activity	1.26112752511053	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	0.604275066192139	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	0.35292941647096	bayes_pls_golite062009
binding	0.0880406080456968	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: