YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24372451, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	409 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372451, gi|....

Description	E-value	Query Range	Subject Range
gi\|68249067, gi\|... - gi\|68249067\|ref\|YP_248179.1\| D-3-phosphoglycerate dehydrogenase [Haemophilus influenzae 86-028NP], g...	410.0	[0..1]	[409..1]
gi\|52425798, gi\|... - gi\|52425798\|ref\|YP_088935.1\| D-3-phosphoglycerate dehydrogenase [Mannheimia succiniciproducens MBEL5...	409.0	[0..1]	[409..1]
SERA_HAEIN - D-3-phosphoglycerate dehydrogenase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 /... SERA_HAEIN - D-3-phosphoglycerate dehydrogenase OS=Haemophilus influenzae GN=serA PE=3 SV=1	409.0	[0..1]	[409..1]
gi\|71555670, gi\|... - gi\|71735117\|ref\|YP_276976.1\| D-3-phosphoglycerate dehydrogenase [Pseudomonas syringae pv. phaseolico...	409.0	[0..1]	[409..21]
gi\|15603536, gi\|... - gi\|15603536\|ref\|NP_246610.1\| D-3-phosphoglycerate dehydrogenase [Pasteurella multocida subsp. multoc...	408.0	[0..2]	[409..3]
gi\|77953234, gi\|... - gi\|77953234\|ref\|ZP_00817644.1\| D-3-phosphoglycerate dehydrogenase [Marinobacter aquaeolei VT8], gi\|7...	408.0	[0..1]	[409..31]
gi\|90327037, gi\|... - gi\|90412059\|ref\|ZP_01220066.1\| phosphoglycerate dehydrogenase [Photobacterium profundum 3TCK], gi\|90...	408.0	[0..1]	[409..1]
gi\|145638620, gi... - gi\|145638620\|ref\|ZP_01794229.1\| D-3-phosphoglycerate dehydrogenase [Haemophilus influenzae PittII], ... gi\|144979311, gi... - gi\|145628841\|ref\|ZP_01784641.1\| D-3-phosphoglycerate dehydrogenase [Haemophilus influenzae 22.1-21],... gi\|53733281 - gi\|53733281\|ref\|ZP_00156300.2\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [H...	408.0	[0..1]	[409..1]
gi\|53733030 - gi\|53733030\|ref\|ZP_00155465.2\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [H...	407.0	[0..1]	[409..1]
gi\|67155503, gi\|... - gi\|67155503\|ref\|ZP_00417131.1\| Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase,... gi\|67155503, gi\|... - gi\|67155503\|ref\|ZP_00417131.1\| Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase,...	406.0	[0..1]	[409..1]

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Predicted Domain #1

Region A:
Residues: [1-409]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKHSLDKDK IKILLLEGVH QSAVDVFERA GYTNIEYHKA SLGDEALHES IKDAHFIGIR  60
   61 SRTQLSADVL KRAEKLIAIG CFCIGTNQVD LATAESLGIP VFNAPFSNTR SVAELVLGEI 120
  121 IMLMRGIPER NAIAHRGGWM KTAAGSYEVR GKTLGVIGYG HIGTQLGILA ETLGMRVVFF 180
  181 DIEDKLPLGN AQQIHSMEQL LAQADVVSLH VPETPQTKDM ISTAEFAAMR KGSIFINASR 240
  241 GTVVDIDALT VALKERHLAG AAIDVFPVEP QSNDDEFISP LRGLDNVLLT PHVGGSTAEA 300
  301 QENIGIEVAG KLAKYSDNGS TVSAVNFPEV SLPMHKGTSR LLHIHQNRPG VLIKINKAFS 360
  361 EKGINIAAQY LQTTAEIGYV VMEVDTHQAE EALVELKAID GTLRTRVLF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1ybaA
Description:	The active form of phosphoglycerate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	3.48670706716817	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.1980358206838	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	1.68027744358887	bayes_pls_golite062009
binding	1.52779917836084	bayes_pls_golite062009
transcription regulator activity	1.00070756595263	bayes_pls_golite062009
oxidoreductase activity	0.9367410227151	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.839863523675468	bayes_pls_golite062009
catalytic activity	0.645256181736122	bayes_pls_golite062009
phosphoglycerate dehydrogenase activity	0.639509916626856	bayes_pls_golite062009
transferase activity	0.576589833246962	bayes_pls_golite062009
nucleic acid binding	0.437542400722334	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
protein binding	0.219210115869644	bayes_pls_golite062009
DNA binding	0.142173841090723	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: