YRC Public Data Repository - Protein Structure Prediction

Protein:	ACL4_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	387 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACL4_YEAST.

Description	E-value	Query Range	Subject Range
gi\|190404885 - gi\|190404885\|gb\|EDV08152.1\| hypothetical protein SCRG_00362 [Saccharomyces cerevisiae RM11-1a] YDR161W - Putative protein of unknown function; non-essential gene; proposed function in rRNA and ribosome bio... ACL4_YEAST - Assembly chaperone of RPL4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ACL4 PE=1 SV=...	0.0	[1..387]	[1..387]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-85	[1..255]	[1..237]
gi\|19113288, gi\|... - gi\|5579043\|emb\|CAB51354.1\| SPBC16D10.01c [Schizosaccharomyces pombe], gi\|19113288\|ref\|NP_596496.1\| h... gi\|19113288 - gi\|19113288\|ref\|NP_596496.1\| hypothetical protein SPBC418.03c [Schizosaccharomyces pombe 972h-]	7.0E-32	[163..270]	[1..91]
gi\|15606587, gi\|... - gi\|2983806\|gb\|AAC07363.1\| putative protein [Aquifex aeolicus VF5], gi\|15606587\|ref\|NP_213967.1\| hypo... gi\|7429603 - pir\|\|H70421 hypothetical protein aq_1402 - Aquifex aeolicus	0.007	[2..74]	[220..288]

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Predicted Domain #1

Region A:
Residues: [1-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELEATIRQ AKEALAENNA KKALKILKPF KSSLKKENAN NVILNEVFAD AYLDNGQVEK  60
   61 AYPILARACE LDPEGQVGGP DKFFTMGQIM GGQDGVSIIT RGIMNISNTG GEMLTNVQVE 120
  121 KIVGGLL

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.5
Match:	1qsaA
Description:	70 KDa soluble lytic transglycosylase (SLT70), superhelical domain; 70 kDa soluble lytic transglycosylase, SLT70
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.26999948840808	bayes_pls_golite062009
protein binding	0.305336743191506	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [128-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVIEIWMTDL CMEPNAEEQC EELIQKAMEL TEGKSPETWS TLGSIKISQQ KFGEAYEAFS  60
   61 QAWNFFELKK QEIGSGINEN GDTTQKAGLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.5
Match:	1qsaA
Description:	70 KDa soluble lytic transglycosylase (SLT70), superhelical domain; 70 kDa soluble lytic transglycosylase, SLT70
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [218-387]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEYVDLLQPL LSLTKMCLEV GAYEVALKVI AAVRDIDEDN IEGYYLEGFT YYLMSKLEIF  60
   61 KLNNPEVSLR PENIYEFNQL IQEVPLDLSH EPISQLIYDS RLALSFALQA GVNADSKDEI 120
  121 VQELLGGANA LLQEIGGPLD PSELTQIKKG DLVNENEDLE ELDIEEEYSD

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.5
Match:	1qsaA
Description:	70 KDa soluble lytic transglycosylase (SLT70), superhelical domain; 70 kDa soluble lytic transglycosylase, SLT70
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: