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View Structure Prediction Details

Protein: YD109_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 647 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YD109_YEAST.

Description E-value Query
Range
Subject
Range
YDL109C - Putative lipase; involved in lipid metabolism; YDL109C is not an essential gene
YD109_YEAST - Putative lipase YDL109C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDL109C PE=1 SV=...
0.0 [1..647] [1..647]
YE7A_SCHPO - Putative lipase spac4a8.10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC4A8.10 PE=2...
SPAC4A8.10 - lipase
0.0 [47..581] [108..692]
gi|21689821, gi|... - gi|51970748|dbj|BAD44066.1| unnamed protein product [Arabidopsis thaliana], gi|42561882|ref|NP_17246...
4.0E-89 [64..426] [323..750]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-81 [64..426] [323..785]
gi|28922217, gi|... - gi|32412922|ref|XP_326941.1| predicted protein [Neurospora crassa], gi|28922217|gb|EAA31464.1| conse...
gi|85098994 - gi|85098994|ref|XP_960700.1| hypothetical protein NCU06655 [Neurospora crassa OR74A]
1.0E-46 [183..435] [2..263]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAGRSADEV LYHNQSSVKL GELERYVITY ELYQGDSIPA DITLDSLWVK IKNTTKLSYK  60
   61 PAYLLGPFIL YCDVRAKDYE SSYKIICSAD KPVFQSNLQA QQKFIAELSL HHIKPRYVWI 120
  121 VDIVSQILFN KETKVTFEIV VGNSKASLKR KIRC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDSLPDKACN ILHTGLSVHR LTTADIWKVP RPIDMSQKSH LVILTHGFQS NVSADMEYLM  60
   61 EEIYKAQMNN PNERLVIKGY MKNACETEKG IKFLGVGLAN YIIDELYDDS VGKISFIGHS 120
  121 LGGLTQTFAI CYIKTKYPYF FKKVEPINFI SLASPLLGIA TST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.39794
Match: 1hqdA_
Description: Lipase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [318-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNYVKMSLSM GIIGTTGQEL GLKDGNYGDK PLLYLLSEES LISVLARFKR RTLYANAVND  60
   61 GIVPLYSSSL LFLDYSQLLQ KLGGQTTAPC DPLFQPEVSP IGELPNHSDV ANDDDGINAS 120
  121 SWNTFWKSKE NNCDKKSKRL MNASVIKSMK SVLLSPCPDA KFFS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
catalytic activity 1.39629727416851 bayes_pls_golite062009
hydrolase activity 1.1444670166202 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.985235528680562 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [482-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPDARVATII HDKIYTEKNL PPPSPTLYEG TAAKEGETRK TRKEMEEIIA RRWHKGMHWR  60
   61 KVVVLLKPDA HNNIIVRRRF SNAYGWPVVD HLVTAHFQRD DPIASPMQDK QFAEEDINMA 120
  121 TGGVEPNKFY SWLTKIEDPS VYHGGIVSTA SQLASSWISK HSSVTD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle