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View Structure Prediction Details

Protein: TOF2_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 771 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOF2_YEAST.

Description E-value Query
Range
Subject
Range
TOF2 - Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase act...
TOF2_YEAST - Topoisomerase 1-associated factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOF2...
0.0 [1..771] [1..771]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKMWRLQIV LVPPSAQDII TFLEARLNTP QSVSPMVQYN EDIITHNNSI NNCSDPSPTS  60
   61 PSSQNSIQSN RSSDFINYLP NCKKFLHFTD GDNTLLQLSN EILTKFDRLY PNFKESIEIV 120
  121 SLQDRHGCDL DSEFIIKDVF ENDGVVLVIL KDELDWSRNQ HISLLQLARQ RRRQDNKPST 180
  181 KSIVTEKRKK ISKEDLSSIS NKDTMHLIAK SSLKNNFINK SRVSTPLMNE ILPLASKYDA 240
  241 L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [242-771]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKEKCPMPLT STVVASNVHK DVKDHARAKE GVVTQGSDNN KENIPSSTQQ QKNDGAKRAE  60
   61 SKDLDLLRNS SEDADYEPAD ENSPQISFDS IDTDFQLSTT SHTNSDMHIQ YSNPSSGAHS 120
  121 PRKSSLEIKV QNKKGDDLPL NDKDIGENCR RIEAFSDEED FNETDNDRAD SFINNSKKAS 180
  181 MGFRDINSDL DSVSFNSDIE NAVQSTQSTK NVVSPPFFPE KELNNRLHQS QGKEALFRLV 240
  241 EKEFPDKSLG AASSTSHAKD VKIQETIRKL NRFKPTGETK VQKRNSITEP YYGKFGIMKK 300
  301 DKPKSITSKG VSLETKHFDD PNTIISGEKF AKFGKIKVKR KTDDVGSKVI EFKRKRNMGN 360
  361 RSLKDIFANA GKPPNAASTI KVVKLMRDPV DNSKDKVEAT SNSTAQEQEQ VSPKLPVMNS 420
  421 TPGKRKNGQA IPSSLERTPQ LKKVKVTRSH SSPSSSSSMS LESSLDSSSS DDSDDDSDSR 480
  481 NVQVKKINFK TSHGPAGNSN GKPMLDVDDN EINTKKYQTP KYVESDEDDQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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