YRC Public Data Repository - Protein Structure Prediction

Protein:	THTR_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	304 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THTR_YEAST.

Description	E-value	Query Range	Subject Range
STR1_ARATH - Thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial OS=Arabidopsis thaliana GN=STR1 PE...	8.0E-72	[3..301]	[77..376]
THTR_YEAST - Thiosulfate sulfurtransferase TUM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TUM1 ... TUM1 - Mitochondrial protein, required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-t... gi\|151945336 - gi\|151945336\|gb\|EDN63579.1\| conserved protein [Saccharomyces cerevisiae YJM789]	3.0E-69	[1..304]	[1..304]
gi\|4406372 - gi\|4406372\|gb\|AAD19957.1\| thiosulfate sulfurtransferase [Datisca glomerata]	2.0E-68	[4..299]	[79..375]
gi\|13362857 - gi\|13362857\|dbj\|BAB36810.1\| putative thiosulfate sulfurtransferase [Escherichia coli O157:H7 str. Sa... gi\|209763320, gi... - gi\|25288801\|pir\|\|G85896 probable thiosulfate sulfurtransferase sseA [imported] - Escherichia coli (s... gi\|12516922, gi\|... - gi\|15803048\|ref\|NP_289078.1\| putative thiosulfate sulfurtransferase [Escherichia coli O157:H7 EDL933... gi\|13362857 - gi\|13362857\|dbj\|BAB36810.1\| putative thiosulfate sulfurtransferase [Escherichia coli O157:H7]	4.0E-68	[1..299]	[54..332]
THTM_RAT - 3-mercaptopyruvate sulfurtransferase OS=Rattus norvegicus GN=Mpst PE=1 SV=3	1.0E-67	[6..300]	[10..289]
THTM_MOUSE - 3-mercaptopyruvate sulfurtransferase OS=Mus musculus GN=Mpst PE=1 SV=3	7.0E-67	[6..303]	[10..293]
gi\|14571545 - gi\|14571545\|gb\|AAK64575.1\| thiosulfate transferase [Triticum aestivum]	1.0E-66	[4..302]	[5..306]
THTM_ECO57 - 3-mercaptopyruvate sulfurtransferase OS=Escherichia coli O157:H7 GN=sseA PE=3 SV=2 gi\|254794471, gi... - gi\|254794471\|ref\|YP_003079308.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str.... gi\|208820412, gi... - gi\|208820412\|ref\|ZP_03260732.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. ... gi\|208813274, gi... - gi\|208813274\|ref\|ZP_03254603.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. ... gi\|217327804, gi... - gi\|217327804\|ref\|ZP_03443887.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. ... gi\|38704097 - gi\|38704097\|ref\|NP_311414.2\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. Sak... gi\|209398755, gi... - gi\|209398755\|ref\|YP_002271995.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str.... gi\|189378625, gi... - gi\|189378625\|gb\|EDU97041.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC50... gi\|189372287, gi... - gi\|189372287\|gb\|EDU90703.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC86... gi\|208808021, gi... - gi\|208808021\|ref\|ZP_03250358.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. ... gi\|195936667 - gi\|195936667\|ref\|ZP_03082049.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. ... gi\|168768617, gi... - gi\|189362246\|gb\|EDU80665.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC44... gi\|168761135, gi... - gi\|189368468\|gb\|EDU86884.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC45... gi\|189003502, gi... - gi\|189003502\|gb\|EDU72488.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC40... gi\|187770700, gi... - gi\|187770700\|gb\|EDU34544.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC41... gi\|161367549 - gi\|161367549\|ref\|NP_289078.2\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 EDL933] gi\|189356654, gi... - gi\|189356654\|gb\|EDU75073.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC44... gi\|188017054, gi... - gi\|188017054\|gb\|EDU55176.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC41...	2.0E-66	[1..299]	[1..279]
gi\|161986479 - gi\|161986479\|ref\|YP_311466.2\| 3-mercaptopyruvate sulfurtransferase [Shigella sonnei Ss046] EG11600 - 3-mercaptopyruvate sulfurtransferase / 3-mercaptopyruvate sulfurtransferase; enhances serine sensiti... gi\|170082131, gi... - gi\|170082131\|ref\|YP_001731451.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli str. K-12 su... gi\|170019196, gi... - gi\|170019196\|ref\|YP_001724150.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli ATCC 8739], ... gi\|194427373, gi... - gi\|194427373\|ref\|ZP_03059923.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli B171], gi\|194... gi\|193064008, gi... - gi\|193064008\|ref\|ZP_03045093.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli E22], gi\|1929... gi\|218706024, gi... - gi\|218706024\|ref\|YP_002413543.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli UMN026], gi\|... gi\|218361814, gi... - gi\|218555046\|ref\|YP_002387959.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli IAI1], gi\|21... gi\|238901686, gi... - gi\|238901686\|ref\|YP_002927482.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli BW2952], gi\|... gi\|251785846, gi... - gi\|251785846\|ref\|YP_003000150.1\| hypothetical protein B21_02375 [Escherichia coli BL21], gi\|24237811... EG11600 - 3-mercaptopyruvate sulfurtransferase / 3-mercaptopyruvate sulfurtransferase; enhances serine sensiti... gi\|253978563, gi... - gi\|254289256\|ref\|YP_003055004.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli BL21(DE3)], ... gi\|253974396, gi... - gi\|254162495\|ref\|YP_003045603.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli B str. REL60... gi\|157156971, gi... - gi\|157156971\|ref\|YP_001463843.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli E24377A], gi... THTM_ECOLI - 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese-like protein) (MST) - Escherichia coli gi\|194437663, gi... - gi\|83586829\|ref\|ZP_00925460.1\| COG2897: Rhodanese-related sulfurtransferase [Escherichia coli 101-1]... gi\|124498687, gi... - gi\|124531241\|ref\|ZP_01701583.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli B], gi\|124498... gi\|89109327, gi\|... - gi\|89109327\|ref\|AP_003107.1\| 3-mercaptopyruvate sulfurtransferase [Escherichia coli str. K-12 substr...	2.0E-66	[1..299]	[1..279]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLFDLISPK AFVKLVASEK VHRIVPVDAT WYLPSWKLDN KVDFLTKPRI PNSIFFDIDA  60
   61 ISDKKSPYPH MFPTKKVFDD AMSNLGVQKD DILVVYDRVG NFSSPRCAWT LGVMGHPKVY 120
  121 LLNNFNQYRE FKYPLDSSKV AAFSPYPKSH YESSESFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	388.37734
Match:	1rhd__
Description:	Rhodanese
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thiosulfate sulfurtransferase activity	4.07143118207301	bayes_pls_golite062009
sulfurtransferase activity	2.90539767285523	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	2.27106357502695	bayes_pls_golite062009
protein tyrosine phosphatase activity	0.83774799640503	bayes_pls_golite062009
binding	0.707400650337243	bayes_pls_golite062009
catalytic activity	0.687308230067573	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.604322283158386	bayes_pls_golite062009
transferase activity	0.302497611306574	bayes_pls_golite062009
protein binding	0.26324773851743	bayes_pls_golite062009
phosphatase activity	0.0565207759893606	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [159-304]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKEIVDYEEM FQLVKSGELA KKFNAFDARS LGRFEGTEPE PRSDIPSGHI PGTQPLPYGS  60
   61 LLDPETKTYP EAGEAIHATL EKALKDFHCT LDPSKPTICS CGTGVSGVII KTALELAGVP 120
  121 NVRLYDGSWT EWVLKSGPEW IAENRD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	388.37734
Match:	1rhd__
Description:	Rhodanese
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: