YRC Public Data Repository - Protein Structure Prediction

Protein:	SLT11_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	364 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLT11_YEAST.

Description	E-value	Query Range	Subject Range
ECM2 - Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association wit... SLT11_YEAST - Pre-mRNA-splicing factor SLT11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM2 PE=1...	4.0E-86	[1..364]	[1..364]
C3H4_ARATH - Zinc finger CCCH domain-containing protein 4 OS=Arabidopsis thaliana GN=At1g07360 PE=2 SV=1	4.0E-80	[10..284]	[20..302]
RBM22 - RNA binding motif protein 22 RBM22_MOUSE - Pre-mRNA-splicing factor RBM22 OS=Mus musculus GN=Rbm22 PE=1 SV=1 gi\|73954184 - gi\|73954184\|ref\|XP_546302.2\| PREDICTED: similar to RNA binding motif protein 22 [Canis familiaris] tr\|M3WPJ5\|M3WPJ5... - RNA binding motif protein 22 OS=Felis catus GN=RBM22 PE=4 SV=1 CCDS34278.1_1 - null gi\|119930522 - gi\|119930522\|ref\|XP_001249809.1\| PREDICTED: similar to Pre-mRNA-splicing factor RBM22 (RNA-binding m... gi\|114602891, gi... - gi\|114602893\|ref\|XP_001167209.1\| PREDICTED: hypothetical protein isoform 1 [Pan troglodytes], gi\|114... RBM22_MACFA - Pre-mRNA-splicing factor RBM22 OS=Macaca fascicularis GN=RBM22 PE=2 SV=1 gi\|208965472, gi... - gi\|60654947\|gb\|AAX32038.1\| RNA binding motif protein 22 [synthetic construct], gi\|208965472\|dbj\|BAG7... gi\|109079367 - gi\|109079367\|ref\|XP_001108861.1\| PREDICTED: similar to RNA binding motif protein 22 isoform 2 [Macac... tr\|G1T1G7\|G1T1G7... - pep:novel chromosome:oryCun2:3:32380281:32388261:-1 gene:ENSOCUG00000011532 transcript:ENSOCUT000000...	1.0E-74	[10..287]	[21..309]
gi\|12858161 - gi\|12858161\|dbj\|BAB31220.1\| unnamed protein product [Mus musculus]	2.0E-74	[10..287]	[21..309]
gi\|2665654 - gi\|2665654\|gb\|AAB88449.1\| polyadenylate binding protein [Petromyzon marinus]	7.0E-72	[100..362]	[2..277]
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1	8.0E-72	[100..362]	[2..276]

Back

Predicted Domain #1

Region A:
Residues: [1-91]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDEINEPPP NICEQCLGDE ANIRMTKIPQ GSECKICTLP FTLYHFKTSK RSNNIIKTLI  60
   61 CVRCATQRNI CQCCMLDSRW HIPIQLRDHL I

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	1.74860109511336	bayes_pls_golite062009
catalytic activity	0.223774911842048	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [92-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLVNEENVMT EEAKNDMMKR FLSLKNVKLG GAQITSDPSE ADNIVDKLKN ILLRATSDGP  60
   61 STPLIKNTTA LYKNEKGANE VKNLEKYASV DISHILKKLP LNESFLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.154902
Match:	1cvjA_
Description:	Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	6.73097473547076	bayes_pls_golite062009
	6.62953239642182	bayes_pls_golite062009
mRNA binding	5.29759606920196	bayes_pls_golite062009
nucleic acid binding	3.81920018903278	bayes_pls_golite062009
binding	3.49612884560266	bayes_pls_golite062009
snRNA binding	3.28448936696877	bayes_pls_golite062009
poly-pyrimidine tract binding	3.11990160533699	bayes_pls_golite062009
single-stranded RNA binding	2.93798024346416	bayes_pls_golite062009
U1 snRNA binding	2.26303528058407	bayes_pls_golite062009
protein binding	1.32954276279597	bayes_pls_golite062009
structural molecule activity	1.29928829870122	bayes_pls_golite062009
transcription regulator activity	1.07788694919471	bayes_pls_golite062009
DNA binding	0.978604858165557	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
transcription factor activity	0.234742017105535	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [199-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPSTKSFFLY NIDASIPEWK ITDTVSQLLG IKKWKDGNSL SLIVNHKAKC GGLRFQSSEL  60
   61 GERFVSKISE TLVTPKGLKR GVLLIDRFR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.154902
Match:	1cvjA_
Description:	Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [288-364]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFIIPWSSGF SAASFGTNTA ENIKLSLSLN KLIQLELGLS FPTKSTDNAK NDKKKTSKKV  60
   61 HKDRSKKSKP RANKLTI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.221849
Match:	1l3kA_
Description:	Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: