YRC Public Data Repository - Protein Structure Prediction

Protein:	SEO1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	593 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEO1_YEAST.

Description	E-value	Query Range	Subject Range
SEO1_YEAST - Probable transporter SEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEO1 PE=1 SV=1 SEO1 - Putative permease, member of the allantoate transporter subfamily of the major facilitator superfami...	0.0	[1..593]	[1..593]
STP9_ARATH - Sugar transport protein 9 OS=Arabidopsis thaliana GN=STP9 PE=1 SV=1	2.0E-86	[132..570]	[21..491]
STC_RICCO - Sugar carrier protein C OS=Ricinus communis GN=STC PE=2 SV=1	2.0E-85	[135..570]	[24..492]
gi\|115470211, gi... - gi\|50508995\|dbj\|BAD31944.1\| putative monosaccharide transport protein MST1 [Oryza sativa Japonica Gr... gi\|125556956 - gi\|125556956\|gb\|EAZ02492.1\| hypothetical protein OsI_24597 [Oryza sativa Indica Group] gi\|11991114 - gi\|11991114\|dbj\|BAB19864.1\| monosaccharide transporter 3 [Oryza sativa]	3.0E-85	[131..570]	[18..490]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-84	[132..570]	[19..490]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1	5.0E-83	[78..571]	[8..529]

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Predicted Domain #1

Region A:
Residues: [1-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSIVKEIIV DPYKRLKWGF IPVKRQVEDL PDDLNSTEIV TISNSIQSHE TAENFITTTS  60
   61 EKDQLHFETS SYSEHKDNVN VTRSYEYRDE ADRPWWRFFD EQEYRINEKE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.351	b.1.18	E set domains
View	Download	0.425	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.291	d.211.1	Ankyrin repeat
View	Download	0.283	d.26.1	FKBP-like
View	Download	0.306	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.425	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.351	b.1.18	E set domains
View	Download	0.306	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.291	d.211.1	Ankyrin repeat
View	Download	0.283	d.26.1	FKBP-like
View	Download	0.239	d.110.3	PYP-like sensor domain (PAS domain)
View	Download	0.218	a.1.1	Globin-like
View	Download	0.201	a.1.1	Globin-like
View	Download	0.201	a.40.1	Calponin-homology domain, CH-domain

Predicted Domain #2

Region A:
Residues: [111-593]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSHNKWYSWF KQGTSFKEKK LLIKLDVLLA FYSCIAYWVK YLDTVNINNA YVSGMKEDLG  60
   61 FQGNDLVHTQ VMYTVGNIIF QLPFLIYLNK LPLNYVLPSL DLCWSLLTVG AAYVNSVPHL 120
  121 KAIRFFIGAF EAPSYLAYQY LFGSFYKHDE MVRRSAFYYL GQYIGILSAG GIQSAVYSSL 180
  181 NGVNGLEGWR WNFIIDAIVS VVVGLIGFYS LPGDPYNCYS IFLTDDEIRL ARKRLKENQT 240
  241 GKSDFETKVF DIKLWKTIFS DWKIYILTLW NIFCWNDSNV SSGAYLLWLK SLKRYSIPKL 300
  301 NQLSMITPGL GMVYLMLTGI IADKLHSRWF AIIFTQVFNI IGNSILAAWD VAEGAKWFAF 360
  361 MLQCFGWAMA PVLYSWQNDI CRRDAQTRAI TLVTMNIMAQ SSTAWISVLV WKTEEAPRYL 420
  421 KGFTFTACSA FCLSIWTFVV LYFYKRDERN NAKKNGIVLY NSKHGVEKPT SKDVETLSVS 480
  481 DEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.30103
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	5.46247398538901	bayes_pls_golite062009
ion transmembrane transporter activity	4.58978526526921	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
anion transmembrane transporter activity	3.94605227012838	bayes_pls_golite062009
cation transmembrane transporter activity	3.88180006470231	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	2.52916479889426	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
binding	0.873217664940684	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
phosphate transmembrane transporter activity	0.312628600969375	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: