| Protein: | PRI2_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 528 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRI2_YEAST.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..528] | [1..528] |
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0.0 | [53..520] | [20..464] |
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0.0 | [53..520] | [20..464] |
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0.0 | [53..520] | [20..464] |
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0.0 | [59..514] | [316..759] |
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0.0 | [38..507] | [9..456] |
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0.0 | [55..516] | [24..468] |
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2.0E-89 | [124..479] | [59..368] |
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Region A: Residues: [1-139] |
1 11 21 31 41 51
| | | | | |
1 MFRQSKRRIA SRKNFSSYDD IVKSELDVGN TNAANQIILS SSSSEEEKKL YARLYESKLS 60
61 FYDLPPQGEI TLEQFEIWAI DRLKILLEIE SCLSRNKSIK EIETIIKPQF QKLLPFNTES 120
121 LEDRKKDYYS HFILRLCFC
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.758 | 0.022 | DNA replication, synthesis of RNA primer | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.681 | 0.010 | DNA replication, synthesis of RNA primer | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.591 | 0.009 | DNA replication, synthesis of RNA primer | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.946 | N/A | N/A | a.185.1 | Gametocyte protein Pfg27 |
| View | Download | 0.660 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.576 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.536 | N/A | N/A | a.116.1 | GTPase activation domain, GAP |
| View | Download | 0.535 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.512 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.506 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.489 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.470 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.468 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.456 | N/A | N/A | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.455 | N/A | N/A | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.443 | N/A | N/A | d.92.2 | beta-N-acetylhexosaminidase-like domain |
| View | Download | 0.440 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.430 | N/A | N/A | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.419 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.409 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.401 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.399 | N/A | N/A | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.396 | N/A | N/A | a.149.1 | RNase III endonuclease catalytic domain |
| View | Download | 0.393 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.376 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.373 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.372 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.360 | N/A | N/A | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.358 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.357 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.354 | N/A | N/A | c.55.3 | Ribonuclease H-like |
| View | Download | 0.353 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.350 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.349 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.344 | N/A | N/A | a.41.1 | Domain of poly(ADP-ribose) polymerase |
| View | Download | 0.342 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.341 | N/A | N/A | a.116.1 | GTPase activation domain, GAP |
| View | Download | 0.339 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.336 | N/A | N/A | a.79.1 | Antitermination factor NusB |
| View | Download | 0.326 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.325 | N/A | N/A | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.324 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.324 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.320 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.315 | N/A | N/A | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.313 | N/A | N/A | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.311 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.309 | N/A | N/A | d.167.1 | Peptide deformylase |
| View | Download | 0.300 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.299 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.298 | N/A | N/A | a.129.1 | GroEL equatorial domain-like |
| View | Download | 0.297 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.297 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.291 | N/A | N/A | a.148.1 | Arp2/3 complex 21 kDa subunit ARPC3 |
| View | Download | 0.280 | N/A | N/A | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.272 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.263 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.261 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.259 | N/A | N/A | b.26.1 | SMAD/FHA domain |
| View | Download | 0.256 | N/A | N/A | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.256 | N/A | N/A | a.149.1 | RNase III endonuclease catalytic domain |
| View | Download | 0.248 | N/A | N/A | d.153.1 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| View | Download | 0.245 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.245 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.237 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.235 | N/A | N/A | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.233 | N/A | N/A | b.34.8 | Fumarylacetoacetate hydrolase, FAH, N-terminal domain |
| View | Download | 0.230 | N/A | N/A | d.163.1 | DNA breaking-rejoining enzymes |
| View | Download | 0.225 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.225 | N/A | N/A | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.222 | N/A | N/A | c.19.1 | FabD/lysophospholipase-like |
| View | Download | 0.221 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.220 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.219 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.214 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.214 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.208 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.207 | N/A | N/A | a.97.1 | An anticodon-binding domain of class I aminoacyl-tRNA synthetases |
| View | Download | 0.207 | N/A | N/A | d.127.1 | Creatinase/aminopeptidase |
| View | Download | 0.202 | N/A | N/A | a.168.1 | GEF domain of SopE toxin |
| View | Download | 0.201 | N/A | N/A | a.59.1 | PAH2 domain |
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Region A: Residues: [140-220] |
1 11 21 31 41 51
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1 RSKELREKFV RAETFLFKIR FNMLTSTDQT KFVQSLDLPL LQFISNEEKA ELSHQLYQTV 60
61 SASLQFQLNL NEEHQRKQYF Q
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.635 | 0.952 | DNA replication initiation | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.661 | 0.952 | DNA replication initiation | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.628 | 0.952 | DNA replication initiation | a.64.1 | Saposin |
| View | Download | 0.898 | 0.952 | DNA replication initiation | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.555 | 0.952 | DNA replication initiation | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.512 | 0.952 | DNA replication initiation | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.501 | 0.952 | DNA replication initiation | a.135.1 | Tetraspanin |
| View | Download | 0.486 | 0.952 | DNA replication initiation | a.126.1 | Serum albumin-like |
| View | Download | 0.461 | 0.952 | DNA replication initiation | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.455 | 0.952 | DNA replication initiation | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.451 | 0.952 | DNA replication initiation | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.417 | 0.952 | DNA replication initiation | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.404 | 0.952 | DNA replication initiation | a.46.1 | Methionine synthase domain |
| View | Download | 0.391 | 0.952 | DNA replication initiation | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.390 | 0.952 | DNA replication initiation | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.378 | 0.952 | DNA replication initiation | a.4.1 | Homeodomain-like |
| View | Download | 0.365 | 0.952 | DNA replication initiation | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.365 | 0.952 | DNA replication initiation | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.363 | 0.952 | DNA replication initiation | a.64.1 | Saposin |
| View | Download | 0.355 | 0.952 | DNA replication initiation | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.352 | 0.952 | DNA replication initiation | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.345 | 0.952 | DNA replication initiation | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.342 | 0.952 | DNA replication initiation | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.342 | 0.952 | DNA replication initiation | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.341 | 0.952 | DNA replication initiation | a.39.1 | EF-hand |
| View | Download | 0.339 | 0.952 | DNA replication initiation | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.333 | 0.952 | DNA replication initiation | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.330 | 0.952 | DNA replication initiation | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.322 | 0.952 | DNA replication initiation | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.321 | 0.952 | DNA replication initiation | a.64.1 | Saposin |
| View | Download | 0.313 | 0.952 | DNA replication initiation | a.118.8 | TPR-like |
| View | Download | 0.309 | 0.952 | DNA replication initiation | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.293 | 0.952 | DNA replication initiation | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.292 | 0.952 | DNA replication initiation | a.29.2 | Bromodomain |
| View | Download | 0.288 | 0.952 | DNA replication initiation | a.4.1 | Homeodomain-like |
| View | Download | 0.283 | 0.952 | DNA replication initiation | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.273 | 0.952 | DNA replication initiation | a.1.1 | Globin-like |
| View | Download | 0.262 | 0.952 | DNA replication initiation | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.262 | 0.952 | DNA replication initiation | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.258 | 0.952 | DNA replication initiation | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.255 | 0.952 | DNA replication initiation | a.4.1 | Homeodomain-like |
| View | Download | 0.255 | 0.952 | DNA replication initiation | b.55.1 | PH domain-like |
| View | Download | 0.251 | 0.952 | DNA replication initiation | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.248 | 0.952 | DNA replication initiation | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.248 | 0.952 | DNA replication initiation | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.240 | 0.952 | DNA replication initiation | a.65.1 | Annexin |
| View | Download | 0.234 | 0.952 | DNA replication initiation | a.130.1 | Chorismate mutase II |
| View | Download | 0.233 | 0.952 | DNA replication initiation | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.230 | 0.952 | DNA replication initiation | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.229 | 0.952 | DNA replication initiation | a.101.1 | Uteroglobin-like |
| View | Download | 0.229 | 0.952 | DNA replication initiation | d.52.7 | Ribosome-binding factor A, RbfA |
| View | Download | 0.225 | 0.952 | DNA replication initiation | a.39.1 | EF-hand |
| View | Download | 0.225 | 0.952 | DNA replication initiation | a.4.11 | RNA polymerase subunit RPB10 |
| View | Download | 0.222 | 0.952 | DNA replication initiation | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.221 | 0.952 | DNA replication initiation | f.1.2 | Diphtheria toxin, middle domain |
| View | Download | 0.218 | 0.952 | DNA replication initiation | a.3.1 | Cytochrome c |
| View | Download | 0.217 | 0.952 | DNA replication initiation | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.217 | 0.952 | DNA replication initiation | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.216 | 0.952 | DNA replication initiation | c.47.1 | Thioredoxin-like |
| View | Download | 0.214 | 0.952 | DNA replication initiation | a.140.4 | Recombination endonuclease VII, C-terminal and dimerization domains |
| View | Download | 0.212 | 0.952 | DNA replication initiation | a.4.1 | Homeodomain-like |
| View | Download | 0.211 | 0.952 | DNA replication initiation | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.208 | 0.952 | DNA replication initiation | d.26.1 | FKBP-like |
| View | Download | 0.204 | 0.952 | DNA replication initiation | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.204 | 0.952 | DNA replication initiation | a.159.2 | FF domain |
| View | Download | 0.201 | 0.952 | DNA replication initiation | a.23.5 | Hemolysin expression modulating protein HHA |
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Region A: Residues: [221-468] |
1 11 21 31 41 51
| | | | | |
1 QEKFIKLPFE NVIELVGNRL VFLKDGYAYL PQFQQLNLLS NEFASKLNQE LIKTYQYLPR 60
61 LNEDDRLLPI LNHLSSGYTI ADFNQQKANQ FSENVDDEIN AQSVWSEEIS SNYPLCIKNL 120
121 MEGLKKNHHL RYYGRQQLSL FLKGIGLSAD EALKFWSEAF TRNGNMTMEK FNKEYRYSFR 180
181 HNYGLEGNRI NYKPWDCHTI LSKPRPGRGD YHGCPFRDWS HERLSAELRS MKLTQAQIIS 240
241 VLDSCQKG
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [469-528] |
1 11 21 31 41 51
| | | | | |
1 EYTIACTKVF EMTHNSASAD LEIGEQTHIA HPNLYFERSR QLQKKQQKLE KEKLFNNGNH 60
61
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.481 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.341 | a.4.1 | Homeodomain-like |
| View | Download | 0.380 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.348 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.398 | d.68.5 | C-terminal domain of ProRS |
| View | Download | 0.332 | d.10.1 | DNA-binding domain |
| View | Download | 0.326 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.298 | a.4.1 | Homeodomain-like |
| View | Download | 0.273 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.255 | a.4.1 | Homeodomain-like |
| View | Download | 0.250 | d.9.2 | Description not found. |
| View | Download | 0.242 | a.4.1 | Homeodomain-like |
| View | Download | 0.236 | d.10.1 | DNA-binding domain |
| View | Download | 0.231 | a.4.1 | Homeodomain-like |
| View | Download | 0.222 | a.4.5 | "Winged helix" DNA-binding domain |
