YRC Public Data Repository - Protein Structure Prediction

Protein:	PLSC_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	303 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLSC_YEAST.

Description	E-value	Query Range	Subject Range
SLC1 - 1-acyl-sn-glycerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to ... PLSC_YEAST - Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204...	8.0E-75	[1..303]	[1..303]
gi\|5002178 - gi\|5002178\|gb\|AAD37345.1\|AF141864_1 AtaAp [Emericella nidulans] gi\|67539938, gi\|... - gi\|67539938\|ref\|XP_663743.1\| hypothetical protein AN6139.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	2.0E-47	[9..259]	[33..281]
gi\|2852623 - gi\|2852623\|gb\|AAC19153.1\| unknown [Homo sapiens]	3.0E-46	[18..257]	[1..238]
gi\|12720314, gi\|... - gi\|15601968\|ref\|NP_245040.1\| hypothetical protein PM0103 [Pasteurella multocida subsp. multocida str...	2.0E-45	[10..251]	[1..238]
PLSC_HAEIN - 1-acyl-sn-glycerol-3-phosphate acyltransferase OS=Haemophilus influenzae GN=plsC PE=3 SV=1 PLSC_HAEIN - 1-acyl-sn-glycerol-3-phosphate acyltransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11... gi\|229812317, gi... - gi\|229844603\|ref\|ZP_04464742.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Haemophilus influenz... gi\|68249333, gi\|... - gi\|68249333\|ref\|YP_248445.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Haemophilus influenzae ...	4.0E-45	[10..252]	[1..239]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-44	[1..266]	[19..285]
gi\|169749448, gi... - gi\|170022914\|ref\|YP_001719419.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pseudotube... gi\|167469329 - gi\|167469329\|ref\|ZP_02334033.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis FV-1... gi\|166962801, gi... - gi\|167418807\|ref\|ZP_02310560.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|167398515, gi... - gi\|167398515\|ref\|ZP_02304039.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|186699856, gi... - gi\|186896830\|ref\|YP_001873942.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pseudotube... gi\|162421401, gi... - gi\|162421401\|ref\|YP_001604892.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis Ang... gi\|166211993, gi... - gi\|166211993\|ref\|ZP_02238028.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|229705478, gi... - gi\|229837355\|ref\|ZP_04457518.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis Pest... gi\|229682232, gi... - gi\|229900893\|ref\|ZP_04516017.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis Nepa... gi\|166008748, gi... - gi\|166008748\|ref\|ZP_02229646.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|108809110, gi... - gi\|108809110\|ref\|YP_653026.1\| putative acyltransferase [Yersinia pestis Antiqua], gi\|108781023\|gb\|AB... gi\|165939859, gi... - gi\|165939859\|ref\|ZP_02228398.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|229690152, gi... - gi\|229842885\|ref\|ZP_04463037.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|165923174, gi... - gi\|165924974\|ref\|ZP_02220806.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|229696932, gi... - gi\|229840566\|ref\|ZP_04460725.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis biov... gi\|25346998 - pir\|\|AC0083 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) [imported] - Yersinia pestis ... gi\|51597689, gi\|... - gi\|51597689\|ref\|YP_071880.1\| putative acyltransferase (LPAAT) [Yersinia pseudotuberculosis IP 32953]... gi\|45437617, gi\|... - gi\|45442751\|ref\|NP_994290.1\| putative acyltransferase [Yersinia pestis biovar Microtus str. 91001], ... Q665W9\|Q665W9_YERPS - Putative acyltransferase (LPAAT) precursor - Yersinia pseudotuberculosis gi\|16120997, gi\|... - gi\|218927865\|ref\|YP_002345740.1\| putative acyltransferase [Yersinia pestis CO92], gi\|16120997\|ref\|NP... gi\|153947585, gi... - gi\|153947585\|ref\|YP_001399575.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pseudotube... gi\|149289704, gi... - gi\|150260296\|ref\|ZP_01917024.1\| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Yersinia pestis CA88... gi\|145597765, gi... - gi\|145597765\|ref\|YP_001161841.1\| acyltransferase [Yersinia pestis Pestoides F], gi\|145209461\|gb\|ABP3...	1.0E-43	[10..251]	[1..237]
PLCA_SHEEP - 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha OS=Ovis aries GN=AGPAT1 PE=2 SV=1	2.0E-43	[2..257]	[8..277]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVIGRFLYY LRSVLVVLAL AGCGFYGVIA SILCTLIGKQ HLAQWITARC FYHVMKLMLG  60
   61 LDVKVVGEEN LAKKPYIMIA NHQSTLDIFM LGRIFPPGCT VTAKKSLKYV PFLGWFMALS 120
  121 GTYFLDRSKR QEAIDTLNKG LENVKKNKRA LWVFPEGTRS YTSELTMLPF KKGAFHLAQQ 180
  181 GKIPIVPVVV SNTSTLVSPK YGVFNRGCMI VRILKPI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.0
Match:	1k30A_
Description:	Glycerol-3-phosphate (1)-acyltransferase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [218-303]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STENLTKDKI GEFAEKVRDQ MVDTLKEIGY SPAINDTTLP PQAIEYAALQ HDKKVNKKIK  60
   61 NEPVPSVSIS NDVNTHNEGS SVKKMH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.610	a.61.1	Retroviral matrix proteins
View	Download	0.607	a.8.2	Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View	Download	0.482	d.58.48	MTH1187-like
View	Download	0.425	d.58.10	Acylphosphatase-like
View	Download	0.315	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View	Download	0.273	a.74.1	Cyclin-like
View	Download	0.267	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.255	a.60.10	Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View	Download	0.252	d.150.1	4'-phosphopantetheinyl transferase
View	Download	0.235	a.77.1	DEATH domain
View	Download	0.235	a.3.1	Cytochrome c
View	Download	0.227	a.3.1	Cytochrome c
View	Download	0.225	a.35.1	lambda repressor-like DNA-binding domains
View	Download	0.214	a.77.1	DEATH domain
View	Download	0.212	a.26.1	4-helical cytokines
View	Download	0.211	a.74.1	Cyclin-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits