YRC Public Data Repository - Protein Structure Prediction

Protein:	NPY1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	384 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPY1_YEAST.

Description	E-value	Query Range	Subject Range
NPY1_YEAST - NADH pyrophosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPY1 PE=1 SV=1 NPY1 - NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucle...	1.0E-99	[1..384]	[1..384]
NUD12_MOUSE - Peroxisomal NADH pyrophosphatase NUDT12 OS=Mus musculus GN=Nudt12 PE=1 SV=1	3.0E-84	[6..376]	[119..462]
NUDT12 - nudix (nucleoside diphosphate linked moiety X)-type motif 12 gi\|117646588 - gi\|117646588\|emb\|CAL37409.1\| hypothetical protein [synthetic construct]	2.0E-83	[6..376]	[119..462]
SPBC1778.03c - NADH pyrophosphatase NPY1_SCHPO - Probable NADH pyrophosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC1778.03c...	4.0E-80	[7..372]	[19..367]
gi\|221233206, gi... - gi\|221233206\|ref\|YP_002515642.1\| MutT-like protein [Caulobacter crescentus NA1000], gi\|220962378\|gb\|... gi\|25397199 - pir\|\|A87282 MutT/nudix family protein [imported] - Caulobacter crescentus gi\|16124521, gi\|... - gi\|16124521\|ref\|NP_419085.1\| MutT/nudix family protein [Caulobacter crescentus CB15], gi\|13421401\|gb...	4.0E-62	[1..372]	[3..312]
NUD19_ARATH - Nudix hydrolase 19, chloroplastic OS=Arabidopsis thaliana GN=NUDT19 PE=1 SV=1	1.0E-61	[1..375]	[38..423]
gi\|15073156 - gi\|15073156\|emb\|CAC41615.1\| Probable mutT/nudix family protein [Sinorhizobium meliloti 1021] gi\|15963981 - gi\|15963981\|ref\|NP_384334.1\| hypothetical protein SMc02903 [Sinorhizobium meliloti 1021]	7.0E-57	[3..372]	[16..322]
gi\|25520219, gi\|... - pir\|\|AE2588 mutT/nudix family protein [imported] - Agrobacterium tumefaciens (strain C58, Dupont), ... gi\|17738417, gi\|... - gi\|17934017\|ref\|NP_530807.1\| mutT/nudix family protein [Agrobacterium tumefaciens str. C58], gi\|1773...	3.0E-54	[2..372]	[16..318]
gi\|14025341, gi\|... - gi\|14025341\|dbj\|BAB51942.1\| mll5500 [Mesorhizobium loti MAFF303099], gi\|13474587\|ref\|NP_106156.1\| hy...	9.0E-47	[8..371]	[19..312]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAVTFFGQ HVLNRVSFLR CSKEFIKKSL NHDSTVFIPF IEGEALISPE NGDLVQLSNS  60
   61 VKSYKNILSA IVPLYTTLLN TTRSRSDESG INVTFLGLLE GTDSAFNFEW SNISYKGTPY 120
  121 FGLDIRVTES TLFKKVDFEP IFSYPKVTRD HIFKQTNEDA SLYSQGKMYL DWLAKYKFCP 180
  181 GCGSPLFPVE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [191-384]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGTKLQCSNE NRNVYCNVRD ARINNVCFPR TDPTVIIALT NSDYSKCCLA RSKKRYGDFV  60
   61 LYSTIAGFME PSETIEEACI REIWEETGIS CKNIDIVRSQ PWPYPCSLMI GCLGIVQFNS 120
  121 KNEVINLNHD DELLDAQWFD TTEIIQALDK YAGGYRVPFK NDINLPGSTT IAFQLINHVC 180
  181 ENYKNLRKTS SSHL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.69897
Match:	1g0sA_
Description:	ADP-ribose pyrophosphatase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits