YRC Public Data Repository - Protein Structure Prediction

Protein:	NOT2_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	191 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOT2_YEAST.

Description	E-value	Query Range	Subject Range
gi\|190405163 - gi\|190405163\|gb\|EDV08430.1\| general negative regulator of transcription subunit 2 [Saccharomyces cer... NOT2_YEAST - General negative regulator of transcription subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 20450... gi\|151941839 - gi\|151941839\|gb\|EDN60195.1\| CCR4-NOT transcriptional complex subunit [Saccharomyces cerevisiae YJM78... gi\|207347087 - gi\|207347087\|gb\|EDZ73388.1\| YDL165Wp-like protein [Saccharomyces cerevisiae AWRI1631] CDC36 - Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regu...	5.0E-61	[1..191]	[1..191]
gi\|76671654, gi\|... - gi\|76671654\|ref\|XP_878827.1\| PREDICTED: similar to CCR4-NOT transcription complex subunit 2 (CCR4-as... gi\|73968685, gi\|... - gi\|73968701\|ref\|XP_861995.1\| PREDICTED: similar to CCR4-NOT transcription complex subunit 2 (CCR4-as... ENSPTRT00000009594 - null ENSCJAT00000003052 - null tr\|M3X8P1\|M3X8P1... - CCR4-NOT transcription complex subunit 2 OS=Felis catus GN=CNOT2 PE=4 SV=1 gi\|109097754, gi... - gi\|109097756\|ref\|XP_001117431.1\| PREDICTED: CCR4-NOT transcription complex, subunit 2 isoform 4 [Mac... CNOT2 - CCR4-NOT transcription complex, subunit 2 gi\|167774085, gi... - gi\|208965942\|dbj\|BAG72985.1\| CCR4-NOT transcription complex, subunit 2 [synthetic construct], gi\|167...	1.0E-56	[2..190]	[353..521]
gi\|21312480, gi\|... - gi\|21312480\|ref\|NP_082358.1\| CCR4-NOT transcription complex, subunit 2 isoform b [Mus musculus], gi\|... gi\|149066929, gi... - gi\|149066932\|gb\|EDM16665.1\| rCG48666, isoform CRA_a [Rattus norvegicus], gi\|149066929\|gb\|EDM16662.1\|...	1.0E-56	[2..190]	[268..436]
gi\|12006939, gi\|... - gi\|18424272\|ref\|NP_568912.1\| VIP2; transcription regulator [Arabidopsis thaliana], gi\|12006939\|gb\|AA...	3.0E-49	[2..191]	[385..547]
ntl-2 - status:Confirmed UniProt:Q10923 protein_id:AAA80691.1	5.0E-44	[2..190]	[182..350]

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Predicted Domain #1

Region A:
Residues: [1-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKFGLKALV PLLKLEDKEL SSTYDHSMTL GADLSSMLYS LGIPRDSQDH RVLDTFQSPW  60
   61 AETSRSEVEP RFFTPESFTN IPGVLQSTVT PPCFNSIQND QQRVALFQDE TLFFLFYKHP 120
  121 GTVIQELTYL ELRKRNWRYH KTLKAWLTKD PMMEPIVSAD GLSERGSYVF FDPQRWEKCQ 180
  181 RDFLLFYNAI M

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits