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View Structure Prediction Details

Protein: LIN1_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 340 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIN1_YEAST.

Description E-value Query
Range
Subject
Range
LIN1 - Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin com...
LIN1_YEAST - Protein LIN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LIN1 PE=1 SV=1
gi|151944102 - gi|151944102|gb|EDN62395.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..340] [1..340]
LIN1_SCHPO - LIN1-like protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC83.09c PE=3 SV=1
SPBC83.09c - GYF domain
3.0E-71 [15..339] [28..400]
CD2B2_MOUSE - CD2 antigen cytoplasmic tail-binding protein 2 OS=Mus musculus GN=Cd2bp2 PE=1 SV=1
2.0E-61 [76..320] [48..321]
gi|17861590 - gi|17861590|gb|AAL39272.1| GH13760p [Drosophila melanogaster]
3.0E-61 [74..320] [4..299]
CD2BP2 - CD2 (cytoplasmic tail) binding protein 2
gi|123993797, gi... - gi|157928270|gb|ABW03431.1| CD2 (cytoplasmic tail) binding protein 2 [synthetic construct], gi|12399...
8.0E-56 [75..320] [48..320]
gi|9955526 - gi|9955526|emb|CAC05465.1| putative protein [Arabidopsis thaliana]
1.0E-54 [10..267] [4..251]
teg-1 - status:Partially_confirmed UniProt:Q9NAH3 protein_id:CAB55087.1
1.0E-42 [69..280] [34..279]
gi|3355658 - gi|3355658|emb|CAA08790.1| SMC2orf [Podocoryne carnea]
2.0E-38 [62..276] [21..251]

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Predicted Domain #1
Region A:
Residues: [1-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYTQYPNSS KLKRNSDRRE HDEKLSDELH NQSTIYEDEE LSRAEYDSDS DSSVEDSTDN  60
   61 ENSGKEMDEK SYEKNEDHVE DHRKRKKSKI QLLDIAEFKK ENLADLDYQI GNSESKVEKG 120
  121 VNIEPFNIDD EIKHGVFDKD GNYIKTENAT ENDQQDNEEW MNDVINTEEV NRLEKEQSVK 180
  181 TQNSRHYMVH EALNLLKFFL VDENETVLES LGRLNKLRKI AISKKNKSLK YVIHGIELLS 240
  241 DLINILEKKG FSEVYEYNRL KVQDAIEEEI FDDSSRIVNH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [281-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTKLWGFKWL NKLDEYHGLY TNYEMSYWQK SYFKNSVIVK FHSEPDRDEN WIHVSCLSFM  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1gyfA_
Description: GYF domain from cd2bp2 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.49601879307777 bayes_pls_golite062009
protein binding 0.396582780419184 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle