YRC Public Data Repository - Protein Structure Prediction

Protein:	GSHB_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	491 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSHB_YEAST.

Description	E-value	Query Range	Subject Range
gi\|15277522 - gi\|15277522\|gb\|AAK93946.1\| glutathione synthetase GSHS1 [Medicago truncatula]	0.0	[3..490]	[88..555]
gi\|9754870 - gi\|9754870\|gb\|AAF98121.1\|AF231137_1 glutathione synthetase precursor [Pisum sativum]	0.0	[8..490]	[89..551]
GSHB_BRAJU - Glutathione synthetase, chloroplastic OS=Brassica juncea GN=GSH2 PE=2 SV=1	0.0	[11..490]	[70..529]
gi\|190407296 - gi\|190407296\|gb\|EDV10563.1\| glutathione synthetase [Saccharomyces cerevisiae RM11-1a] GSHB_YEAST - Glutathione synthetase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSH2 PE=1 SV=1 GSH2 - Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutam...	0.0	[1..491]	[1..491]
gi\|5531229 - gi\|5531229\|emb\|CAB51026.1\| glutathione synthetase [Arabidopsis thaliana]	0.0	[6..490]	[74..538]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[6..490]	[45..509]
gi\|7799808 - gi\|7799808\|emb\|CAB91078.1\| homoglutathione synthetase [Glycine max]	0.0	[11..490]	[39..498]

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Predicted Domain #1

Region A:
Residues: [1-356]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHYPPSKDQ LNELIQEVNQ WAITNGLSMY PPKFEENPSN ASVSPVTIYP TPIPRKCFDE  60
   61 AVQIQPVFNE LYARITQDMA QPDSYLHKTT EALALSDSEF TGKLWSLYLA TLKSAQYKKQ 120
  121 NFRLGIFRSD YLIDKKKGTE QIKQVEFNTV SVSFAGLSEK VDRLHSYLNR ANKYDPKGPI 180
  181 YNDQNMVISD SGYLLSKALA KAVESYKSQQ SSSTTSDPIV AFIVQRNERN VFDQKVLELN 240
  241 LLEKFGTKSV RLTFDDVNDK LFIDDKTGKL FIRDTEQEIA VVYYRTGYTT TDYTSEKDWE 300
  301 ARLFLEKSFA IKAPDLLTQL SGSKKIQQLL TDEGVLGKYI SDAEKKSSLL KTFVKI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [416-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELIEPELNEN NIILRDNKSY NEPIISELGI YGCVLFNDEQ VLSNEFSGSL LRSKFNTSNE  60
   61 GGVAAGFGCL DSIILY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	852.9794
Match:	2hgsA_
Description:	Eukaryotic glutathione synthetase, substrate-binding domain; Eukaryotic glutathione synthetase ATP-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [357-415]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPLDDTKLGR EGKRLALSEP SKYVLKPQRE GGGNNVYKEN IPNFLKGIEE RHWDAYILM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	852.9794
Match:	2hgsA_
Description:	Eukaryotic glutathione synthetase, substrate-binding domain; Eukaryotic glutathione synthetase ATP-binding domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits