YRC Public Data Repository - Protein Structure Prediction

Protein:	GLE1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	538 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLE1_YEAST.

Description	E-value	Query Range	Subject Range
GLE1 - Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component... GLE1_YEAST - Nucleoporin GLE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GLE1 PE=1 SV=1	6.0E-75	[1..538]	[1..538]
GLE1_MOUSE - Nucleoporin GLE1 OS=Mus musculus GN=Gle1 PE=1 SV=2	3.0E-51	[16..509]	[153..659]
gi\|119608210, gi... - gi\|55665335\|emb\|CAH71064.1\| GLE1 RNA export mediator homolog (yeast) [Homo sapiens], gi\|55663119\|emb...	1.0E-50	[16..509]	[151..658]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-46	[2..370]	[213..587]
gi\|45383668, gi\|... - gi\|9800486\|gb\|AAF99314.1\|AF272033_1 fast myosin heavy chain isoform 2 [Gallus gallus], gi\|45383668\|r...	6.0E-46	[2..370]	[1202..1576]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1	1.0E-45	[2..370]	[1196..1570]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFVFDEVFN SDTDSPEFEE TCSTTSSTSS QCPTPEPSPA IKLPSFTKVG TKKLVNESVV  60
   61 ILDPALENAL RDLNLQSKLI PINEPIVAAS SIIVPHSTNM PLPRASHSSL LDNAKNSNAT 120
  121 APLLEAIEES FQRKMQNLVL ANQKEIQSIR ENKRRVEEQR KRKEEEERKR KEAEEKAKRE 180
  181 QELLRQKKDE EERKRKEAEA KLAQQKQEEE RKKIEEQNEK ERQLKKEHEA KLLQQKDKLG 240
  241 KAVTNFDKIS KMFWHYKDKI AQIKQDIVLP IKKADVNVRN LLSRHKRKIN PKFGQLTNSN 300
  301 QQLFKIQNEL TQLINDT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.522879
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [318-538]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGDSLAYHWI LNFIAKAVVH QAETEVRVKP ESALPLGKLT LYLLVQFPEL QELFMARLVK  60
   61 KCPFVIGFTC EIDTEKGRQN MGWKRNNENK WEDNTSYDER MGGILSLFAI ITRLQLPQEF 120
  121 ITTTSHPFPI ALSWHILARI CNTPLNLITN THFVILGSWW DAAAVQFLQA YGNQASKLLI 180
  181 LIGEELTSRM AEKKYVGAAR LRILLEAWQN NNMESFPEMS P

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [351-538]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLGKLTLYL LVQFPELQEL FMARLVKKCP FVIGFTCEID TEKGRQNMGW KRNNENKWED  60
   61 NTSYDERMGG ILSLFAIITR LQLPQEFITT TSHPFPIALS WHILARICNT PLNLITNTHF 120
  121 VILGSWWDAA AVQFLQAYGN QASKLLILIG EELTSRMAEK KYVGAARLRI LLEAWQNNNM 180
  181 ESFPEMSP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	55.39794
Match:	PF07817.4
Description:	No description for PF07817.4 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits