| Protein: | FRE8_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 686 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRE8_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..686] | [1..686] |
|
|
0.0 | [28..526] | [331..925] |
|
|
0.0 | [28..526] | [254..830] |
|
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0.0 | [28..526] | [282..868] |
|
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0.0 | [28..526] | [301..901] |
|
|
0.0 | [28..526] | [320..907] |
|
Region A: Residues: [1-142] |
1 11 21 31 41 51
| | | | | |
1 MNLKSIVSWF KEHLPSFDVD VDKHFRTLRV RKYSQICLLI SFIIICVIIP LMNYLLLTDK 60
61 FFKICHHLKH HVFNRRSWVH KTHMYHKQSL QLCLICFVFT SFFVIQGANG DLLEITKRMG 120
121 RISVALMPPL LFLTLRPSPL PH
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.562 | a.26.1 | 4-helical cytokines |
| View | Download | 0.473 | a.25.1 | Ferritin-like |
| View | Download | 0.416 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.397 | a.7.7 | BAG domain |
| View | Download | 0.562 | a.26.1 | 4-helical cytokines |
| View | Download | 0.473 | a.25.1 | Ferritin-like |
| View | Download | 0.472 | a.26.1 | 4-helical cytokines |
| View | Download | 0.416 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.397 | a.7.7 | BAG domain |
| View | Download | 0.384 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.365 | a.24.3 | Cytochromes |
| View | Download | 0.360 | a.2.7 | tRNA-binding arm |
| View | Download | 0.355 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.350 | a.26.1 | 4-helical cytokines |
| View | Download | 0.348 | a.7.1 | Spectrin repeat |
| View | Download | 0.348 | a.47.2 | t-snare proteins |
| View | Download | 0.344 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.337 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.333 | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.328 | d.65.1 | Hedgehog/DD-pepidase |
| View | Download | 0.314 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.301 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.301 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.292 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.290 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.273 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.265 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.253 | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.248 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.248 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.247 | a.74.1 | Cyclin-like |
| View | Download | 0.247 | a.24.3 | Cytochromes |
| View | Download | 0.239 | a.24.1 | Apolipoprotein |
| View | Download | 0.226 | c.14.1 | ClpP/crotonase |
| View | Download | 0.225 | a.118.1 | ARM repeat |
| View | Download | 0.222 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.220 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.208 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.203 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
|
Region A: Residues: [143-264] |
1 11 21 31 41 51
| | | | | |
1 TLYLALLPLH KWISRIVVLE SILHTWFYLY YMYINDTLYV KMRKLPNIYG VIALGLFLLI 60
61 AITSVRYARR WSYRVFYYVH YVSTWLILVF LHYHARPGIS YYTTLNVLIL TGQIVYRLHI 120
121 TN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| cation transmembrane transporter activity | 3.03953772177035 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.97347219787596 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 2.75731726445742 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.59951851289794 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.29266587906929 | bayes_pls_golite062009 |
| binding | 0.979727257352345 | bayes_pls_golite062009 |
| protein binding | 0.291685656235254 | bayes_pls_golite062009 |
|
Region A: Residues: [265-393] |
1 11 21 31 41 51
| | | | | |
1 VTRVTIVPIS SSLSLLEFPL TDLPKKPILP GGHLRINIYH RNFLRRFFSH LIPFQHPFTI 60
61 ASIPSDNLVR LIIRNGHFPL RTNEKYYITG AFEPELSFIS KPTVPFNITT KSSKNPFRNN 120
121 SSALINSPL
|
| Detection Method: | |
| Confidence: | 40.69897 |
| Match: | 1ib0A_ |
| Description: | cytochrome b5 reductase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 0.923528499740225 | bayes_pls_golite062009 |
| protein binding | 0.144900113694048 | bayes_pls_golite062009 |
|
Region A: Residues: [394-571] |
1 11 21 31 41 51
| | | | | |
1 NFLIKAQRVF MCVGGSGISF GLPLLRILNF NGVNVRLLWV SRDYKDLEVL NHFKNNFEGM 60
61 EIYISGTEGN EQDIEIDYID YHDCAADIND EVRSISSSGR VSELGDNSML SDGNPQPTEP 120
121 NENTALLSKK STLRNHHPPK TSDIPDINAD DEIDFTYAFS RSKSRKNTAQ GTLTTHSS
|
| Detection Method: | |
| Confidence: | 40.69897 |
| Match: | 1ib0A_ |
| Description: | cytochrome b5 reductase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [572-686] |
1 11 21 31 41 51
| | | | | |
1 FNGSSVFRQP KIIEPPAQDP CLEAAPKKIR IPAGVKVFFG RPTLGDKDYE WCLQTECDAE 60
61 TDSIQCCRWA NQGRDHAEYL SQVWVLAAGP RGLIESTKRW ATDGGLHFHG ESFAL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.336 | a.1.1 | Globin-like |
| View | Download | 0.210 | a.1.2 | alpha-helical ferredoxin |
