YRC Public Data Repository - Protein Structure Prediction

Protein:	DOS2_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	310 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DOS2_YEAST.

Description	E-value	Query Range	Subject Range
DOS2_YEAST - Protein DOS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DOS2 PE=1 SV=1 DOS2 - Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytopla...	2.0E-72	[1..310]	[1..310]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-55	[14..270]	[57..301]
Sap47-PF - The gene Synapse-associated protein 47kD is referred to in FlyBase by the symbol Dmel\Sap47 (CG8884,...	6.0E-55	[23..247]	[135..346]
gi\|18413928 - gi\|18413928\|ref\|NP_567396.1\| BSD domain-containing protein [Arabidopsis thaliana]	5.0E-53	[14..270]	[8..252]
SPAC22A12.14c - BSD domain protein, unknown biological role YF3E_SCHPO - BSD domain-containing protein C22A12.14c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=S...	2.0E-51	[37..290]	[11..274]
gi\|18204811 - gi\|18204811\|gb\|AAH21480.1\| Bsdc1 protein [Mus musculus]	4.0E-46	[35..245]	[4..212]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFFYEEQVA CIEDDKISNS HTKETGSTEN TENNELQSRD DKTNEAFQKL EEEVNKRYEK  60
   61 TTSAFKKLVI EKDDGIEINL PISNETTETA QKYLKKLDEN IHSVESLAQS YWSKMKTKNF 120
  121 WSGFSSFDNA AENDSNDKDE NSKENEIAVG GNRTEAELRT LSKDK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.215	a.77.1	DEATH domain
View	Download	0.269	d.198.1	Type III secretory system chaperone
View	Download	0.209	d.54.1	Enolase N-terminal domain-like

Predicted Domain #2

Region A:
Residues: [166-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVYLDNKMDL QLDPFDVDEK TEEICSILQG DKDISKLMND IVPHKISYKD FWHIYFLQRN  60
   61 KILDKESKRK EILSKKEKET EEKEVEWDDE E

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	18.886057
Match:	PF03909
Description:	BSD domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [257-310]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEDDDKVEA VADNKSKGET KVAVSQEGLK DVSDHVGLAN KDESKDDDDD DDWE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.202	a.5.2	UBA-like
View	Download	0.406	g.63.1	Mollusk pheromone

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits