YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|20808679
Organism:	Caldanaerobacter subterraneus subsp. tengcongensis
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|20808679.

Description	E-value	Query Range	Subject Range
gi\|25316695 - pir\|\|A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125) gi\|15612676, gi\|... - gi\|15612676\|ref\|NP_240979.1\| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi\|10172725\|db...	268.0	[0..3]	[244..2]
gi\|7469455 - pir\|\|S76163 hypothetical protein - Synechocystis sp. (strain PCC 6803) Y955_SYNY3 - Uncharacterized tRNA/rRNA methyltransferase slr0955 OS=Synechocystis sp. (strain ATCC 27184 / PCC 68... Y955_SYNY3 - Uncharacterized tRNA/rRNA methyltransferase slr0955 OS=Synechocystis sp. (strain PCC 6803 / Kazusa) ...	259.0	[0..2]	[243..121]
gi\|25316722 - pir\|\|H97287 rRNA methylase, YACO B. subtilis ortholog [imported] - Clostridium acetobutylicum gi\|15026220, gi\|... - gi\|15896402\|ref\|NP_349751.1\| rRNA methylase [Clostridium acetobutylicum ATCC 824], gi\|15026220\|gb\|AA...	257.0	[0..2]	[246..5]
gi\|48859457, gi\|... - gi\|67875040\|ref\|ZP_00504559.1\| RNA methyltransferase TrmH, group 3 [Clostridium thermocellum ATCC 27... gi\|196198671, gi... - gi\|196251913\|ref\|ZP_03150578.1\| RNA methyltransferase, TrmH family, group 3 [Clostridium thermocellu...	257.0	[0..2]	[245..33]
gi\|106895728, gi... - gi\|158319524\|ref\|YP_001512031.1\| RNA methyltransferase [Alkaliphilus oremlandii OhILAs], gi\|15813972...	257.0	[0..7]	[243..6]
gi\|48892550, gi\|... - gi\|71674113\|ref\|ZP_00671860.1\| RNA methyltransferase TrmH, group 3 [Trichodesmium erythraeum IMS101]...	255.0	[0..2]	[243..38]
gi\|52001802, gi\|... - gi\|52783952\|ref\|YP_089781.1\| YacO [Bacillus licheniformis ATCC 14580], gi\|52346454\|gb\|AAU39088.1\| Ya...	254.0	[0..1]	[243..1]
gi\|86558795, gi\|... - gi\|86610253\|ref\|YP_479015.1\| RNA methyltransferase [Synechococcus sp. JA-2-3B'a(2-13)], gi\|86558795\|... gi\|86610253 - gi\|86610253\|ref\|YP_479015.1\| RNA methyltransferase, TrmH family, group 3 [Cyanobacteria bacterium Ye...	253.0	[0..4]	[243..105]
gi\|150015025, gi... - gi\|82749273\|ref\|ZP_00911735.1\| RNA methyltransferase TrmH, group 3 [Clostridium beijerincki NCIMB 80...	253.0	[0..2]	[243..56]
gi\|81300928, gi\|... - gi\|81300928\|ref\|YP_401136.1\| RNA methyltransferase TrmH, group 3 [Synechococcus elongatus PCC 7942],...	252.0	[0..5]	[244..242]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNGDIIYGR NPVIEAIRSG KEIEKIYVSK TAGGNISKII GMAKEAGIVV STADSDTLKR  60
   61 LAQTPNHQGV VAVGALYKYF DVTDILNYAE EKKEKPFLLI LDEITDPHNM GAIIRSAEAF 120
  121 GVHGVIIPKR RSAGINATVV KASAGAVEYI KVAKVSNINS TIRDLKEKGL WIIGTDAKAE 180
  181 KSFEELDYDF PLALVIGSEG KGISRLVLEN CDFVIKIPMK GKINSLNASV AASILMYNIL 240
  241 SKRQGKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.154902
Match:	1gz0A
Description:	RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.77771076540343	bayes_pls_golite062009
methyltransferase activity	4.0901595540349	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01958090893547	bayes_pls_golite062009
rRNA methyltransferase activity	3.659149846946	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.59156540645412	bayes_pls_golite062009
tRNA methyltransferase activity	2.52700462137917	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.29844424181442	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.0947794364355	bayes_pls_golite062009
transferase activity	1.84002196534744	bayes_pls_golite062009
catalytic activity	1.16774040077235	bayes_pls_golite062009
rRNA (guanosine-2'-O-)-methyltransferase activity	0.778889412216451	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.47764353619615	bayes_pls_golite062009
N-methyltransferase activity	0.0655574594365502	bayes_pls_golite062009
structural constituent of ribosome	0.0643795631250501	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: