YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25290026
Organism:	Brucella melitensis
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25290026.

Description	E-value	Query Range	Subject Range
gi\|254729967 - gi\|254729967\|ref\|ZP_05188545.1\| signal peptidase I [Brucella abortus bv. 4 str. 292] gi\|254717155 - gi\|254717155\|ref\|ZP_05178966.1\| signal peptidase I [Brucella ceti M13/05/1] gi\|254718801 - gi\|254718801\|ref\|ZP_05180612.1\| signal peptidase I [Brucella sp. 83/13] gi\|23501547, gi\|... - gi\|23501547\|ref\|NP_697674.1\| signal peptidase I [Brucella suis 1330], gi\|23347458\|gb\|AAN29589.1\| sig... gi\|82699548 - gi\|82699548\|ref\|YP_414122.1\| signal peptidase S26A:Signal peptidase [Brucella melitensis biovar Abor... gi\|254693418 - gi\|254693418\|ref\|ZP_05155246.1\| signal peptidase I [Brucella abortus bv. 3 str. Tulya] gi\|62195752, gi\|... - gi\|62289620\|ref\|YP_221413.1\| signal peptidase I [Brucella abortus bv. 1 str. 9-941], gi\|62195752\|gb\|... gi\|254697071 - gi\|254697071\|ref\|ZP_05158899.1\| signal peptidase I [Brucella abortus bv. 2 str. 86/8/59] gi\|82615649 - gi\|82615649\|emb\|CAJ10636.1\| Bacterial signal peptidase S26A:Signal peptidase [Brucella melitensis bi... gi\|225640546, gi... - gi\|225852181\|ref\|YP_002732414.1\| signal peptidase I [Brucella melitensis ATCC 23457], gi\|225640546\|g... gi\|254688936 - gi\|254688936\|ref\|ZP_05152190.1\| signal peptidase I [Brucella abortus bv. 6 str. 870] gi\|148559685, gi... - gi\|148559685\|ref\|YP_001258644.1\| signal peptidase I [Brucella ovis ATCC 25840], gi\|148370942\|gb\|ABQ6... gi\|254709786 - gi\|254709786\|ref\|ZP_05171597.1\| signal peptidase I [Brucella pinnipedialis B2/94] gi\|161335441, gi... - gi\|161618630\|ref\|YP_001592517.1\| signal peptidase I [Brucella canis ATCC 23365], gi\|161335441\|gb\|ABX... gi\|254713788 - gi\|254713788\|ref\|ZP_05175599.1\| signal peptidase I [Brucella ceti M644/93/1] gi\|189023874, gi... - gi\|189023874\|ref\|YP_001934642.1\| Bacterial signal peptidase S26A [Brucella abortus S19], gi\|18901944... gi\|254701448 - gi\|254701448\|ref\|ZP_05163276.1\| signal peptidase I [Brucella suis bv. 5 str. 513] gi\|254707632 - gi\|254707632\|ref\|ZP_05169460.1\| signal peptidase I [Brucella pinnipedialis M163/99/10]	296.0	[0..19]	[278..1]
gi\|115255924, gi... - gi\|116251276\|ref\|YP_767114.1\| putative signal peptidase [Rhizobium leguminosarum bv. viciae 3841], g...	263.0	[0..21]	[268..1]
gi\|14027202, gi\|... - gi\|14027202\|dbj\|BAB54156.1\| signal peptidase I [Mesorhizobium loti MAFF303099], gi\|13476441\|ref\|NP_1...	263.0	[0..23]	[268..4]
gi\|86281129, gi\|... - gi\|86357027\|ref\|YP_468919.1\| signal peptidase I protein [Rhizobium etli CFN 42], gi\|86281129\|gb\|ABC9...	262.0	[0..23]	[268..2]
gi\|68189943, gi\|... - gi\|69279687\|ref\|ZP_00614493.1\| Signal peptidase I [Mesorhizobium sp. BNC1], gi\|68189943\|gb\|EAN04605....	262.0	[0..19]	[268..1]
gi\|15888376, gi\|... - gi\|17934941\|ref\|NP_531731.1\| prokaryotic type I signal peptidase [Agrobacterium tumefaciens str. C58... gi\|25290024, gi\|... - pir\|\|AI2703 prokaryotic type I signal peptidase [imported] - Agrobacterium tumefaciens (strain C58, ...	261.0	[0..23]	[267..2]
gi\|150027420, gi... - gi\|150395905\|ref\|YP_001326372.1\| signal peptidase I [Sinorhizobium medicae WSM419], gi\|150027420\|gb\|...	261.0	[0..23]	[268..2]
gi\|15964824 - gi\|15964824\|ref\|NP_385177.1\| signal peptidase I transmembrane protein [Sinorhizobium meliloti 1021] gi\|15074003 - gi\|15074003\|emb\|CAC45650.1\| Probable signal peptidase I transmembrane protein [Sinorhizobium melilot...	259.0	[0..23]	[267..2]
gi\|27353327, gi\|... - gi\|27380173\|ref\|NP_771702.1\| type I signal peptidase [Bradyrhizobium japonicum USDA 110], gi\|2735332...	257.0	[0..21]	[267..1]
gi\|3176882 - gi\|3176882\|gb\|AAD02938.1\| prokaryotic type I signal peptidase SipF [Bradyrhizobium japonicum]	256.0	[0..21]	[267..1]

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Predicted Domain #1

Region A:
Residues: [1-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRAALAVIR SRIGSGDTMS VSSKNETKKS GGLGETISVI VQALLLALII RTLLFQPFSI  60
   61 PSGSMRPTLL EGDYLFVSKY AYGYSRYSLP FGLDLFSGRI WSAEPKRGDV VVFKLPSDTS 120
  121 VDYIKRVIGL PGDRVQMRGG VLYINDKPVK RERVGTINNP DVTEENRPVE VYRETLPNGV 180
  181 TYDTLELAPN SIGDDTRVFE VPAGHYFMMG DNRDNSLDSR FGVGYVPFEN LVGRANIIFF 240
  241 SIADKASPLE IWKWPTDVRF NRLFTWVSGE PHTAVTGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.69897
Match:	1t7dA
Description:	Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	0.485843348899278	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.237734983138449	bayes_pls_golite062009
hydrolase activity	0.188292586303013	bayes_pls_golite062009
protein binding	0.0579980138351139	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: