YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|17986450, gi\|...
Organism:	Brucella melitensis bv. 1 str. 16M
Length:	300 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|17986450, gi|....

Description	E-value	Query Range	Subject Range
gi\|82616766 - gi\|82616766\|emb\|CAJ11853.1\| Acyl-CoA thioesterase [Brucella melitensis biovar Abortus 2308] gi\|62196886, gi\|... - gi\|62290754\|ref\|YP_222547.1\| TesB, acyl-CoA thioesterase II [Brucella abortus bv. 1 str. 9-941], gi\|... gi\|254690042 - gi\|254690042\|ref\|ZP_05153296.1\| Acyl-CoA thioesterase [Brucella abortus bv. 6 str. 870] gi\|254694531 - gi\|254694531\|ref\|ZP_05156359.1\| Acyl-CoA thioesterase [Brucella abortus bv. 3 str. Tulya] gi\|254696156 - gi\|254696156\|ref\|ZP_05157984.1\| Acyl-CoA thioesterase [Brucella abortus bv. 2 str. 86/8/59] gi\|254731074 - gi\|254731074\|ref\|ZP_05189652.1\| Acyl-CoA thioesterase [Brucella abortus bv. 4 str. 292] gi\|82700665 - gi\|82700665\|ref\|YP_415239.1\| Acyl-CoA thioesterase [Brucella melitensis biovar Abortus 2308]	380.0	[0..1]	[300..1]
gi\|23348767, gi\|... - gi\|23502749\|ref\|NP_698876.1\| acyl-CoA thioesterase II [Brucella suis 1330], gi\|23348767\|gb\|AAN30791....	379.0	[0..1]	[298..1]
gi\|66047520, gi\|... - gi\|66047520\|ref\|YP_237361.1\| Acyl-CoA thioesterase [Pseudomonas syringae pv. syringae B728a], gi\|632...	368.0	[0..11]	[298..1]
gi\|71557703, gi\|... - gi\|71737150\|ref\|YP_276466.1\| acyl-CoA thioesterase II [Pseudomonas syringae pv. phaseolicola 1448A],...	367.0	[0..11]	[298..1]
gi\|25304482 - pir\|\|AC2915 acyl-CoA thioesterase II [imported] - Agrobacterium tumefaciens (strain C58, Dupont) gi\|17741270, gi\|... - gi\|17936631\|ref\|NP_533421.1\| acyl-CoA thioesterase II [Agrobacterium tumefaciens str. C58], gi\|17741...	366.0	[0..8]	[299..4]
gi\|21957791, gi\|... - gi\|22124950\|ref\|NP_668373.1\| acyl-CoA thioesterase II [Yersinia pestis KIM], gi\|21957791\|gb\|AAM84624... gi\|45435496, gi\|... - gi\|45440639\|ref\|NP_992178.1\| acyl-CoA thioesterase II [Yersinia pestis biovar Microtus str. 91001], ...	364.0	[0..1]	[297..1]
gi\|37527715, gi\|... - gi\|37527715\|ref\|NP_931060.1\| acyl-CoA thioesterase II (TEII) [Photorhabdus luminescens subsp. laumon...	363.0	[0..11]	[297..1]
gi\|28871792, gi\|... - gi\|28871792\|ref\|NP_794411.1\| acyl-CoA thioesterase II [Pseudomonas syringae pv. tomato str. DC3000],... tr\|Q87W94\|Q87W94... - Acyl-CoA thioesterase II OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=tesB PE=4 SV=1	362.0	[0..11]	[298..1]
gi\|152986560, gi... - gi\|94412725\|ref\|ZP_01292630.1\| hypothetical protein PaerP_01005464 [Pseudomonas aeruginosa PA7], gi\|...	362.0	[0..11]	[298..1]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEEKSGIE QTAAMRELLS ILDLETLEMD LFRGNSPQVG WQRVFGGQVI GQALIAAQRT  60
   61 VDPERHVHSL HAYFVRPGDP AIPIIYEVDR IRDGSSFSTR RVLAKQHGKA IFTLSASFQI 120
  121 DEGGLDHQMP MPEGLPQPEQ LVGDHDIKEK YLDMAPPGVR KYWERERPIE IKPVSLTHYF 180
  181 SREKLEPVQH VWVRARGLVP DDRALQAAIL AYLSDMTLLD TSLHPHGRFI FDRDMQVASL 240
  241 DHAMWFHRPC RLDDWLLYTQ DAPSASGARG FNRGALYTRD GVLIASVAQE GLIRVHEKNK 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	95.522879
Match:	1c8uA
Description:	Thioesterase II (TesB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acyl-CoA thioesterase activity	2.60197973503923	bayes_pls_golite062009
CoA hydrolase activity	2.3187640589669	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	1.14159464719086	bayes_pls_golite062009
thiolester hydrolase activity	1.14125301545576	bayes_pls_golite062009
catalytic activity	0.74605540351792	bayes_pls_golite062009
binding	0.358549779743531	bayes_pls_golite062009
hydrolase activity	0.093543122203219	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: