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View Structure Prediction Details

Protein: CCDS1876.1_1
Organism: Chlorocebus aethiops
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCDS1876.1_1.

Description E-value Query
Range
Subject
Range
PELI2 - pellino homolog 2 (Drosophila)
0.0 [1..418] [1..420]
gi|114653181 - gi|114653181|ref|XP_522860.2| PREDICTED: pellino 2 [Pan troglodytes]
0.0 [1..418] [1..420]
gi|76660216 - gi|76660216|ref|XP_612354.2| PREDICTED: similar to pellino 2 [Bos taurus]
0.0 [1..418] [1..420]
gi|149033568, gi... - gi|157822359|ref|NP_001100729.1| pellino 2 [Rattus norvegicus], gi|149033568|gb|EDL88366.1| similar ...
0.0 [1..418] [1..419]
PELI2_MOUSE - E3 ubiquitin-protein ligase pellino homolog 2 OS=Mus musculus GN=Peli2 PE=1 SV=2
0.0 [1..418] [1..419]
gi|57093365 - gi|57093365|ref|XP_538508.1| PREDICTED: similar to pellino protein [Canis familiaris]
0.0 [1..418] [1..418]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSPDQENHP SKAPVKYGEL IVLGYNGSLP NGDRGRRKSR FALFKRPKAN GVKPSTVHIA  60
   61 CTPQAAKAIS NKDQHSISYT LSRAQTVVVE YTHDSNTDMF QIGRSTESPI DFVVTDTVPG 120
  121 SQSNSDTQSV QSTISRFACR IICERNPPFT ARIYAAGFDS SKNIFLG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [168-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKAAKWKTSD GQMDGLTTNG VLVMHPRNGF TEDSKPGIWR EISVCGNVFS LRETRSAQQR  60
   61 GKMVEIETNQ LQDGSLIDLC GATLLWRTAE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [258-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSHTPTVKH LEALRQEINA ARPQCPVGFN TLAFPSMKRK DVVDEKQPWV YLNCGHVHGY  60
   61 HNWGNKEERD G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [329-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDRECPMCRS VGPYVPLWLG CEAGFYVDAG PPTHAFSPCG HVCSEKTTAY WSQIPLPHGT  60
   61 HTFHAACPFC AHQLAGEQGY IRLIFQGPLD 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.12
Match: 1e4uA
Description: Not-4 N-terminal RING finger domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.06923986676721 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
small conjugating protein ligase activity 0.324292450240439 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.248014157054608 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle