YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|42518299, gi\|...
Organism:	Lactobacillus johnsonii NCC 533
Length:	757 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|42518299, gi|....

Description	E-value	Query Range	Subject Range
gi\|23003420 - gi\|23003420\|ref\|ZP_00047083.1\| COG1554: Trehalose and maltose hydrolases (possible phosphorylases) [... gi\|116094473, gi... - gi\|23003420\|ref\|ZP_00047083.1\| hypothetical protein Lgas_03001518 [Lactobacillus gasseri ATCC 33323]...	914.0	[0..1]	[756..2]
gi\|58255433, gi\|... - gi\|58338116\|ref\|YP_194701.1\| maltose phosphorylase [Lactobacillus acidophilus NCFM], gi\|58255433\|gb\|... gi\|227869611, gi... - gi\|227902705\|ref\|ZP_04020510.1\| maltose phosphorylase [Lactobacillus acidophilus ATCC 4796], gi\|2278...	902.0	[0..2]	[756..1]
gi\|25516978, gi\|... - pir\|\|AG1710 maltosephosphorylase homolog lin2226 [imported] - Listeria innocua (strain Clip11262), g... gi\|16801291 - gi\|16801291\|ref\|NP_471559.1\| hypothetical protein lin2226 [Listeria innocua Clip11262]	871.0	[0..3]	[753..4]
gi\|69244472, gi\|... - gi\|69244472\|ref\|ZP_00602888.1\| Glycoside hydrolase, family 65, C-terminal:Glycoside hydrolase, famil... gi\|48826299 - ref\|ZP_00287521.1\| COG1554: Trehalose and maltose hydrolases (possible phosphorylases) [Enterococcus...	864.0	[0..2]	[756..4]
gi\|224501080 - gi\|224501080\|ref\|ZP_03669387.1\| maltose phosphorylase [Listeria monocytogenes FSL R2-561] gi\|16411591, gi\|... - pir\|\|AI1339 maltosephosphorylase homolog lmo2121 [imported] - Listeria monocytogenes (strain EGD-e),... gi\|16804160 - gi\|16804160\|ref\|NP_465645.1\| hypothetical protein lmo2121 [Listeria monocytogenes EGD-e]	862.0	[0..3]	[753..4]
gi\|254937008 - gi\|254937008\|ref\|ZP_05268705.1\| maltose phosphorylase [Listeria monocytogenes F6900] gi\|153191644, gi... - gi\|254912681\|ref\|ZP_05262693.1\| maltose phosphorylase [Listeria monocytogenes J2818], gi\|153191644\|r... gi\|47015837, gi\|... - gi\|47095833\|ref\|ZP_00233438.1\| glycosyl transferase, family 65 [Listeria monocytogenes str. 1/2a F68... gi\|254899178 - gi\|254899178\|ref\|ZP_05259102.1\| maltose phosphorylase [Listeria monocytogenes J0161] gi\|224500213 - gi\|224500213\|ref\|ZP_03668562.1\| maltose phosphorylase [Listeria monocytogenes Finland 1988]	862.0	[0..3]	[753..4]
gi\|225877190, gi... - gi\|226224728\|ref\|YP_002758835.1\| maltosephosphorylase [Listeria monocytogenes Clip81459], gi\|2258771... gi\|46881628, gi\|... - gi\|46908357\|ref\|YP_014746.1\| glycosyl transferase family protein [Listeria monocytogenes str. 4b F23... gi\|47091791, gi\|... - gi\|47091791\|ref\|ZP_00229586.1\| glycosyl transferase, family 65 [Listeria monocytogenes str. 4b H7858...	861.0	[0..3]	[754..4]
gi\|116333027, gi... - gi\|116333027\|ref\|YP_794554.1\| maltosephosphorylase [Lactobacillus brevis ATCC 367], gi\|116098374\|gb\|...	854.0	[0..2]	[752..1]
gi\|15988492, gi\|... - gi\|15988493\|pdb\|1H54\|B Chain B, Maltose Phosphorylase From Lactobacillus Brevis, gi\|15988492\|pdb\|1H5...	852.0	[0..2]	[740..1]
gi\|27544256 - gi\|27544256\|dbj\|BAC54904.1\| maltose phosphorylase [Bacillus sp. RK-1] gi\|60729610 - gi\|60729610\|pir\|\|JC7917 maltose phosphorylase (EC 2.4.1.8) - Bacillus sp. (Strain RK-1)	849.0	[0..4]	[749..5]

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Predicted Domain #1

Region A:
Residues: [1-757]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRIFEVDP WKVTTHEFSK EDKRLQESIT AIGNDYMGMR GNFEEGYSGD TLQGTYLAGV  60
   61 WFPDKTVVGW WKNGYPKYFG KTPNAPSFIG IGITVNGEKI DLAKVKFSDF ELSLDMHQGL 120
  121 LSRSFIYEGK DVKVRFEFER FLHIVQKEAA LIKVKATVLE GKAKIDFDST LDGTVVNEDS 180
  181 NYDERFWIPL GENKDTKTIQ VKTKPNPYEV PQFTVLLKES LRHNGELIQT EVSTKEAKLS 240
  241 EKFSVELSEG QSYELEKDVI VVTSRDVEEK DQASVAEDLM NKLQSKSFEE NLADHTAEWQ 300
  301 KRWDMSDVEI SGDAAAQQGI RFNIAQLFMT YYGEDERLNV GPKGFTGEKY GGATYWDTEA 360
  361 YIVPMYLGIT NPSVTKALLQ YRHNQLPGAC HNAKEQGLPG ALFPMVTFNG IECHNEWEIT 420
  421 FEEIHRNADI PHAIAMYTEY TGDDSYVKNE GMDVLVGTAR FWAARVHWSK WRNKYVMHGV 480
  481 TGPNEYENNV NNNWFTNTMA RWLLKYTLER LPLATKEAQE RVHVTEEEKE KWQDIVDKIY 540
  541 LPEDKELGIF LQQDDFLDKE IRPVSEIEDQ RPINQHWSWD KILRSPFIKQ ADVLQGIYFF 600
  601 PENYTKDQKE KNFDFYEPLT VHESSLSPSI HSVLAAELGK KDKAVELYER TARLDLDNYN 660
  661 NDTVDGLHIT SMSGSWLAIV QGFAGMRYDH DQLKFKPFIP DNWDHYSFKI NYRGRLIKVY 720
  721 VDHQETKISL LKGKDLEIFV NDKKVTLKEG ESECLKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1h54A
Description:	Lactobacillus maltose phosphorylase, central domain; Lactobacillus maltose phosphorylase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
racemase and epimerase activity, acting on carbohydrates and derivatives	1.21567860634685	bayes_pls_golite062009
racemase and epimerase activity	1.19295069153058	bayes_pls_golite062009
catalytic activity	1.14137378674629	bayes_pls_golite062009
isomerase activity	0.62004466537384	bayes_pls_golite062009
trehalase activity	0.0297597913054797	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: