YRC Public Data Repository - Protein Structure Prediction

Protein:	PER1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	357 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PER1_YEAST.

Description	E-value	Query Range	Subject Range
PER1 - Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the G... PER1_YEAST - Protein PER1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PER1 PE=1 SV=1	0.0	[1..357]	[1..357]
gi\|20147283, gi\|... - gi\|20147283\|gb\|AAM10355.1\| AT5g62130/mtg10_150 [Arabidopsis thaliana], gi\|18424554\|ref\|NP_568951.1\| ...	0.0	[5..350]	[8..333]
SPAC823.07 - GPI-phospholipase A2 activity regulator PER1_SCHPO - Protein PER1 homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC823.07 PE=3 SV=1	2.0E-85	[6..350]	[12..315]
CE18091 - status:Partially_confirmed UniProt:O61975 protein_id:AAC17768.1	6.0E-75	[5..344]	[6..301]
gi\|85014345, gi\|... - gi\|85014345\|ref\|XP_955668.1\| hypothetical protein ECU09_1170 [Encephalitozoon cuniculi GB-M1], gi\|19... gi\|19173236 - ref\|NP_597039.1\| hypothetical protein [Encephalitozoon cuniculi]	6.0E-48	[100..343]	[51..268]

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Predicted Domain #1

Region A:
Residues: [1-98]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLAVVVTLL VHCFLVTCSP GDNLDEFIDC TYACEYNRRC PNSQINYIDP ETNMFHDIEF  60
   61 FDTPPLYSKL LFWDCISDCD YQCQHIITRW RIDEEEEI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.595	0.970	cellular manganese ion homeostasis	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.534	0.970	cellular manganese ion homeostasis	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.508	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.354	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.475	0.970	cellular manganese ion homeostasis	a.64.1	Saposin
View	Download	0.303	0.970	cellular manganese ion homeostasis	a.24.17	Group V grass pollen allergen
View	Download	0.245	0.970	cellular manganese ion homeostasis	d.102.1	Regulatory factor Nef
View	Download	0.419	0.970	cellular manganese ion homeostasis	d.228.1	Replication modulator SeqA, C-terminal DNA-binding domain
View	Download	0.328	0.970	cellular manganese ion homeostasis	d.226.1	GIY-YIG endonuclease
View	Download	0.406	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.402	0.970	cellular manganese ion homeostasis	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.390	0.970	cellular manganese ion homeostasis	a.4.1	Homeodomain-like
View	Download	0.382	0.970	cellular manganese ion homeostasis	a.118.1	ARM repeat
View	Download	0.376	0.970	cellular manganese ion homeostasis	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.367	0.970	cellular manganese ion homeostasis	d.56.1	GroEL-intermediate domain like
View	Download	0.348	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.345	0.970	cellular manganese ion homeostasis	d.129.1	TATA-box binding protein-like
View	Download	0.327	0.970	cellular manganese ion homeostasis	a.1.1	Globin-like
View	Download	0.321	0.970	cellular manganese ion homeostasis	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.318	0.970	cellular manganese ion homeostasis	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.313	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.312	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.311	0.970	cellular manganese ion homeostasis	a.7.5	Tubulin chaperone cofactor A
View	Download	0.307	0.970	cellular manganese ion homeostasis	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.303	0.970	cellular manganese ion homeostasis	a.142.1	PTS-regulatory domain, PRD
View	Download	0.288	0.970	cellular manganese ion homeostasis	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.287	0.970	cellular manganese ion homeostasis	d.58.1	4Fe-4S ferredoxins
View	Download	0.287	0.970	cellular manganese ion homeostasis	c.13.2	Anti-sigma factor antagonist SpoIIaa
View	Download	0.275	0.970	cellular manganese ion homeostasis	a.64.1	Saposin
View	Download	0.261	0.970	cellular manganese ion homeostasis	c.84.1	Phosphoglucomutase, first 3 domains
View	Download	0.260	0.970	cellular manganese ion homeostasis	a.1.1	Globin-like
View	Download	0.258	0.970	cellular manganese ion homeostasis	d.58.9	RuBisCO, large subunit, small (N-terminal) domain
View	Download	0.253	0.970	cellular manganese ion homeostasis	a.42.1	MDM2
View	Download	0.243	0.970	cellular manganese ion homeostasis	f.34.1	Mechanosensitive channel protein MscS (YggB), transmembrane region
View	Download	0.239	0.970	cellular manganese ion homeostasis	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.236	0.970	cellular manganese ion homeostasis	a.39.1	EF-hand
View	Download	0.227	0.970	cellular manganese ion homeostasis	d.50.3	PI-Pfui intein middle domain
View	Download	0.226	0.970	cellular manganese ion homeostasis	d.58.39	Glutamyl tRNA-reductase catalytic, N-terminal domain
View	Download	0.225	0.970	cellular manganese ion homeostasis	a.2.3	Chaperone J-domain
View	Download	0.225	0.970	cellular manganese ion homeostasis	d.50.3	PI-Pfui intein middle domain
View	Download	0.220	0.970	cellular manganese ion homeostasis	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View	Download	0.214	0.970	cellular manganese ion homeostasis	a.181.1	Antibiotic binding domain of TipA-like multidrug resistance regulators
View	Download	0.212	0.970	cellular manganese ion homeostasis	a.77.1	DEATH domain
View	Download	0.208	0.970	cellular manganese ion homeostasis	b.84.2	Rudiment single hybrid motif

Predicted Domain #2

Region A:
Residues: [99-357]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQFHGKWPFL RVLGTQEFFS TIFSIGNFIP HYKGFVKFSR IIREEGDRRR KNSRSILIWN  60
   61 YLYVTVAGML AWTASSVFHC RDLIITEKLD YFFAGLTVLT GFHAIFARMT SMFLYPKIAQ 120
  121 AFTASVAAIF ALHILRLYVD WSYTYNMRFN IFFGVLQYIL LIMLSCQNYH ALQKQKLMGE 180
  181 FKKTAYSSFK RQIFKLCVIP ILLVIVTTMA MSLELFDFFS YEWQIDAHAL WHLCTIWPSW 240
  241 VLYDFFLEDY AYWGNRQLY

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits