YRC Public Data Repository - Protein Structure Prediction

Protein:	AAKG_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	322 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AAKG_YEAST.

Description	E-value	Query Range	Subject Range
gi\|8215682, gi\|1... - gi\|8215682\|gb\|AAF73987.1\|AF214519_1 AMP-activated protein kinase gamma subunit [Homo sapiens], sp\|Q9...	1.0E-52	[15..318]	[152..453]
AAKG2_MOUSE - 5'-AMP-activated protein kinase subunit gamma-2 OS=Mus musculus GN=Prkag2 PE=1 SV=1	4.0E-52	[9..318]	[243..552]
gi\|220948160 - gi\|220948160\|gb\|ACL86623.1\| SNF4Agamma-PC [synthetic construct] SNF4Agamma-PK, S... - The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dme...	1.0E-51	[15..318]	[423..723]
AAKG_YEAST - 5'-AMP-activated protein kinase subunit gamma OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288... SNF4 - Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p... gi\|190407068 - gi\|190407068\|gb\|EDV10335.1\| nuclear protein SNF4 [Saccharomyces cerevisiae RM11-1a] gi\|207345399 - gi\|207345399\|gb\|EDZ72233.1\| YGL115Wp-like protein [Saccharomyces cerevisiae AWRI1631]	1.0E-51	[1..322]	[1..322]
AAKG3_PIG - 5'-AMP-activated protein kinase subunit gamma-3 OS=Sus scrofa GN=PRKAG3 PE=1 SV=2	1.0E-50	[15..318]	[152..453]
SNF4_KLULA - Nuclear protein SNF4 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / ... SNF4_KLULA - Nuclear protein SNF4 OS=Kluyveromyces lactis GN=SNF4 PE=3 SV=2	4.0E-48	[10..322]	[15..328]
AAKG_BOVIN, AAKG... - (P58108) 5'-AMP-activated protein kinase, gamma-1 subunit (AMPK gamma-1 chain) (AMPKg), (P58108) 5'-...	9.0E-48	[3..318]	[5..323]
gi\|1335860 - gi\|1335860\|gb\|AAC52580.1\| 5'-AMP-activated protein kinase, gamma-1 subunit	1.0E-47	[22..318]	[21..315]

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Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPTQDSQEK VSIEQQLAVE SIRKFLNSKT SYDVLPVSYR LIVLDTSLLV KKSLNVLLQN  60
   61 SIVSAPLWDS KTSRFAGLLT TTDFINVIQY YFSNPDKFEL VDKLQLDGLK DIERALGVDQ 120
  121 LDTASIHPSR PLFEACLKML ESRSGRIPLI DQDEETHREI VVSVLTQYRI LKFVALNCRE 180
  181 THFLKIPIGD LNIITQDNMK SCQMTTPVID VIQMLTQGRV SSVPIIDENG YLINVYEAYD 240
  241 VLGLIKGGIY NDLSLSVGEA LMRRSDDFEG VYTCTKNDKL STIMDNIRKA RVHRFFVVDD 300
  301 VGRLVGVLTL SDILKYILLG SN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.0
Match:	1jr1A_
Description:	Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits