YRC Public Data Repository - Protein Structure Prediction

Protein:	YIA6_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	373 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIA6_YEAST.

Description	E-value	Query Range	Subject Range
gi\|151943152 - gi\|151943152\|gb\|EDN61487.1\| NAD+ transporter [Saccharomyces cerevisiae YJM789] gi\|190406229 - gi\|190406229\|gb\|EDV09496.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] YIA6 - Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YE... YIA6_YEAST - Mitochondrial nicotinamide adenine dinucleotide transporter 1 OS=Saccharomyces cerevisiae (strain AT...	6.0E-83	[1..373]	[1..373]
UCP3_PIG - Mitochondrial uncoupling protein 3 OS=Sus scrofa GN=UCP3 PE=2 SV=1	1.0E-81	[69..371]	[5..303]
ADT3_BOVIN - ADP/ATP translocase 3 OS=Bos taurus GN=SLC25A6 PE=1 SV=3	2.0E-81	[72..365]	[3..298]
SLC25A31 - solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 gi\|117645348 - gi\|117645348\|emb\|CAL38140.1\| hypothetical protein [synthetic construct] HGNC:25319\|MIM:6... - carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31	3.0E-81	[64..366]	[7..309]
UCP3_MOUSE - Mitochondrial uncoupling protein 3 OS=Mus musculus GN=Ucp3 PE=1 SV=1	4.0E-81	[69..371]	[5..303]
UCP3_RAT - Mitochondrial uncoupling protein 3 OS=Rattus norvegicus GN=Ucp3 PE=2 SV=1	7.0E-81	[69..371]	[5..303]

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Predicted Domain #1

Region A:
Residues: [1-72]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQTDNPVPN CGLLPEQQYC SADHEEPLLL HEEQLIFPDH SSQLSSADII EPIKMNSSTE  60
   61 SIIGTTLRKK WV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.271	b.36.1	PDZ domain-like
View	Download	0.314	a.60.1	SAM/Pointed domain
View	Download	0.257	a.61.1	Retroviral matrix proteins
View	Download	0.384	a.60.4	DNA repair protein Rad51, N-terminal domain
View	Download	0.588	a.112.1	Description not found.
View	Download	0.234	a.60.5	Barrier-to-autointegration factor, BAF
View	Download	0.205	a.150.1	Anti-sigma factor AsiA

Predicted Domain #2

Region A:
Residues: [73-373]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSSTQITAL SGAFAGFLSG VAVCPLDVAK TRLQAQGLQT RFENPYYRGI MGTLSTIVRD  60
   61 EGPRGLYKGL VPIVLGYFPT WMIYFSVYEF SKKFFHGIFP QFDFVAQSCA AITAGAASTT 120
  121 LTNPIWVVKT RLMLQSNLGE HPTHYKGTFD AFRKLFYQEG FKALYAGLVP SLLGLFHVAI 180
  181 HFPIYEDLKV RFHCYSRENN TNSINLQRLI MASSVSKMIA SAVTYPHEIL RTRMQLKSDI 240
  241 PDSIQRRLFP LIKATYAQEG LKGFYSGFTT NLVRTIPASA ITLVSFEYFR NRLENISTMV 300
  301 I

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.55
Match:	1is2A
Description:	Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits