YRC Public Data Repository - Protein Structure Prediction

Protein:	LEXA_SALTY
Organism:	Salmonella enterica subsp. enterica serovar Typhimurium
Length:	202 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEXA_SALTY.

Description	E-value	Query Range	Subject Range
gi\|2293118 - gi\|2293118\|gb\|AAB68649.1\| LexA [unidentified cloning vector]	6.0E-60	[1..202]	[1..202]
gi\|89110764, gi\|... - gi\|89110764\|ref\|AP_004544.1\| DNA-binding transcriptional repressor [Escherichia coli str. K-12 subst... gi\|254796045, gi... - gi\|254796045\|ref\|YP_003080882.1\| DNA-binding transcriptional repressor of SOS regulon [Escherichia c... gi\|253975880, gi... - gi\|254163979\|ref\|YP_003047087.1\| LexA repressor [Escherichia coli B str. REL606], gi\|253975880\|gb\|AC... LEXA_SHIDS - LexA repressor OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=lexA PE=3 SV=1 LEXA_ECOUT - LexA repressor OS=Escherichia coli (strain UTI89 / UPEC) GN=lexA PE=3 SV=1 gi\|254037039, gi... - gi\|254037039\|ref\|ZP_04871116.1\| LexA repressor [Escherichia sp. 1_1_43], gi\|226840145\|gb\|EEH72147.1\|... LEXA_SHIBS - LexA repressor OS=Shigella boydii serotype 4 (strain Sb227) GN=lexA PE=3 SV=1 gi\|13364503, gi\|... - gi\|15834280\|ref\|NP_313053.1\| LexA repressor [Escherichia coli O157:H7 str. Sakai], gi\|13364503\|dbj\|B... gi\|253775329, gi... - gi\|254290729\|ref\|YP_003056477.1\| LexA repressor [Escherichia coli BL21(DE3)], gi\|253980036\|gb\|ACT457... gi\|251787299, gi... - gi\|251787299\|ref\|YP_003001603.1\| hypothetical protein B21_03875 [Escherichia coli BL21], gi\|24237957... LEXA_ECOBW - LexA repressor OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=lexA PE=3 SV=1 gi\|237703600, gi... - gi\|237703600\|ref\|ZP_04534081.1\| regulator for SOS(lexA) regulon [Escherichia sp. 3_2_53FAA], gi\|2269... gi\|227886951, gi... - gi\|227886951\|ref\|ZP_04004756.1\| repressor lexA [Escherichia coli 83972], gi\|227836092\|gb\|EEJ46558.1\|... gi\|75229390, gi\|... - gi\|75229390\|ref\|ZP_00715942.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|75238581, gi\|... - gi\|75238581\|ref\|ZP_00722570.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_ECOHS - LexA repressor OS=Escherichia coli O9:H4 (strain HS) GN=lexA PE=3 SV=1 gi\|194426760, gi... - gi\|75211926\|ref\|ZP_00711981.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|188495882, gi... - gi\|75514804\|ref\|ZP_00737033.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_ECOL5 - LexA repressor OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=lexA PE=3 SV=1 LEXA_SHISS - LexA repressor OS=Shigella sonnei (strain Ss046) GN=lexA PE=3 SV=1 LEXA_SHIF8 - LexA repressor OS=Shigella flexneri serotype 5b (strain 8401) GN=lexA PE=3 SV=1 gi\|190907727, gi... - gi\|75241073\|ref\|ZP_00724947.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|75258963, gi\|... - gi\|75258963\|ref\|ZP_00730331.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_SHIB3 - LexA repressor OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=lexA PE=3 SV=1 LEXA_ECO24 - LexA repressor OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=lexA PE=3 SV=1 gi\|194437208, gi... - gi\|83587136\|ref\|ZP_00925765.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... sp\|B7UPK4\|LEXA_ECO27 - LexA repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=lexA PE=3 SV=1 LEXA_ECOL6 - LexA repressor OS=Escherichia coli O6 GN=lexA PE=3 SV=1 LEXA_ECO27 - LexA repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=lexA PE=3 SV=1 gi\|217325242, gi... - gi\|217325242\|ref\|ZP_03441326.1\| LexA repressor [Escherichia coli O157:H7 str. TW14588], gi\|217321463... LEXA_ECO8A - LexA repressor OS=Escherichia coli O8 (strain IAI1) GN=lexA PE=3 SV=1 LEXA_ECO45 - LexA repressor OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=lexA PE=3 SV=1 LEXA_ECO81 - LexA repressor OS=Escherichia coli O81 (strain ED1a) GN=lexA PE=3 SV=1 LEXA_ECO55 - LexA repressor OS=Escherichia coli (strain 55989 / EAEC) GN=lexA PE=3 SV=1 LEXA_ECO7I - LexA repressor OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=lexA PE=3 SV=1 LEXA_ECOLU - LexA repressor OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=lexA PE=3 SV=1 LEXA_ECOLC - LexA repressor OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=lexA PE=3 SV=1 LEXA_ECOSM - LexA repressor OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=lexA PE=3 SV=1 gi\|170769501, gi... - gi\|170769501\|ref\|ZP_02903954.1\| LexA repressor [Escherichia albertii TW07627], gi\|170121558\|gb\|EDS90... gi\|195935810 - gi\|195935810\|ref\|ZP_03081192.1\| LexA repressor [Escherichia coli O157:H7 str. EC4024] gi\|208725781, gi... - gi\|208805980\|ref\|ZP_03248317.1\| LexA repressor [Escherichia coli O157:H7 str. EC4206], gi\|208725781\|... LEXA_ECOK1 - LexA repressor OS=Escherichia coli O1:K1 / APEC GN=lexA PE=3 SV=1 gi\|208812141, gi... - gi\|208812141\|ref\|ZP_03253470.1\| LexA repressor [Escherichia coli O157:H7 str. EC4045], gi\|208733418\|... gi\|124501126, gi... - gi\|124527683\|ref\|ZP_01699118.1\| SOS-response transcriptional repressor, LexA [Escherichia coli B], g... gi\|208738799, gi... - gi\|208818676\|ref\|ZP_03258996.1\| LexA repressor [Escherichia coli O157:H7 str. EC4042], gi\|208738799\|... LEXA_ECO5E - LexA repressor OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=lexA PE=3 SV=1 LEXA_ECOSE - LexA repressor OS=Escherichia coli (strain SE11) GN=lexA PE=3 SV=1 LEXA_ECOLI - LexA repressor (EC 3.4.21.88) - Escherichia coli gi\|168755195, gi... - gi\|189357457\|gb\|EDU75876.1\| LexA repressor [Escherichia coli O157:H7 str. EC4401], gi\|168755195\|ref\|... gi\|189368539, gi... - gi\|189368539\|gb\|EDU86955.1\| LexA repressor [Escherichia coli O157:H7 str. EC4501], gi\|168760890\|ref\|... gi\|189364225, gi... - gi\|189364225\|gb\|EDU82644.1\| LexA repressor [Escherichia coli O157:H7 str. EC4486], gi\|168766285\|ref\|... LEXA_SHIFL - LexA repressor OS=Shigella flexneri GN=lexA PE=3 SV=1 gi\|187769832, gi... - gi\|187769832\|gb\|EDU33676.1\| LexA repressor [Escherichia coli O157:H7 str. EC4196], gi\|168774382\|ref\|... gi\|24054674, gi\|... - gi\|24115367\|ref\|NP_709877.1\| LexA repressor [Shigella flexneri 2a str. 301], gi\|24054674\|gb\|AAN45584... gi\|189001764, gi... - gi\|189001764\|gb\|EDU70750.1\| LexA repressor [Escherichia coli O157:H7 str. EC4076], gi\|168780437\|ref\|... EG10533 - transcriptional repressor of SOS regulon / Global regulator (repressor) for SOS regulon; dimeric LEXA_ECOL6 - LexA repressor OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=lexA PE=3 SV=1 gi\|189375044, gi... - gi\|189375044\|gb\|EDU93460.1\| LexA repressor [Escherichia coli O157:H7 str. EC869], gi\|168784640\|ref\|Z... gi\|30064633, gi\|... - gi\|30064633\|ref\|NP_838804.1\| LexA repressor [Shigella flexneri 2a str. 2457T], gi\|30042892\|gb\|AAP186... gi\|168798312, gi... - gi\|189379093\|gb\|EDU97509.1\| LexA repressor [Escherichia coli O157:H7 str. EC508], gi\|168798312\|ref\|Z... LEXA_ECO57 - LexA repressor OS=Escherichia coli O157:H7 GN=lexA PE=3 SV=1 LEXA_ECODH - LexA repressor OS=Escherichia coli (strain K12 / DH10B) GN=lexA PE=3 SV=1 EG10533 - transcriptional repressor of SOS regulon / Global regulator (repressor) for SOS regulon; dimeric gi\|15804636, gi\|... - gi\|15804636\|ref\|NP_290677.1\| LexA repressor [Escherichia coli O157:H7 EDL933], gi\|12518992\|gb\|AAG592... gi\|188015015, gi... - gi\|188015015\|gb\|EDU53137.1\| LexA repressor [Escherichia coli O157:H7 str. EC4113], gi\|168750824\|ref\|...	2.0E-59	[1..202]	[1..202]
gi\|15988320, gi\|... - gi\|15988321\|pdb\|1JHH\|B Chain B, Lexa S119a Mutant, gi\|15988320\|pdb\|1JHH\|A Chain A, Lexa S119a Mutant	9.0E-59	[1..202]	[1..202]
gi\|47768, gi\|552... - pir\|\|ILEBT lexA protein - Salmonella typhimurium, gi\|552020\|gb\|AAA27157.1\| lexA [Salmonella enteric... gi\|47768\|emb\|CAA... - lexA, LexA protein [Salmonella typhimurium]	1.0E-58	[1..202]	[1..202]
gi\|229706255, gi... - gi\|229836571\|ref\|ZP_04456737.1\| DNA-binding transcriptional repressor of SOS regulon [Yersinia pesti... gi\|229696545, gi... - gi\|229840179\|ref\|ZP_04460338.1\| DNA-binding transcriptional repressor of SOS regulon [Yersinia pesti... LEXA_YERPE - LexA repressor OS=Yersinia pestis GN=lexA PE=3 SV=1 gi\|229690571, gi... - gi\|229842261\|ref\|ZP_04462416.1\| DNA-binding transcriptional repressor of SOS regulon [Yersinia pesti... gi\|149290047, gi... - gi\|150260639\|ref\|ZP_01917367.1\| LexA repressor [Yersinia pestis CA88-4125], gi\|149290047\|gb\|EDM40124... LEXA_YERPP - LexA repressor OS=Yersinia pestis (strain Pestoides F) GN=lexA PE=3 SV=1 LEXA_YERPS - LexA repressor OS=Yersinia pseudotuberculosis GN=lexA PE=3 SV=1 LEXA_YERPG - LexA repressor OS=Yersinia pestis bv. Antiqua (strain Angola) GN=lexA PE=3 SV=1 gi\|165926677, gi... - gi\|165926677\|ref\|ZP_02222509.1\| LexA repressor [Yersinia pestis biovar Orientalis str. F1991016], gi... LEXA_YERP3 - LexA repressor OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=lexA PE=3 SV=1 gi\|165936375, gi... - gi\|89104133\|ref\|ZP_01176685.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_YERPA - LexA repressor OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=lexA PE=3 SV=1 LEXA_YERPN - LexA repressor OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=lexA PE=3 SV=1 gi\|22124486, gi\|... - gi\|22124486\|ref\|NP_667909.1\| LexA repressor [Yersinia pestis KIM], gi\|21957278\|gb\|AAM84160.1\|AE01365... LEXA_YERPS - LexA repressor OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=lexA PE=3 SV=1 gi\|45435180, gi\|... - gi\|45440324\|ref\|NP_991863.1\| LexA repressor [Yersinia pestis biovar Microtus str. 91001], gi\|4543518... gi\|166204939, gi... - gi\|166213964\|ref\|ZP_02239999.1\| LexA repressor [Yersinia pestis biovar Antiqua str. B42003004], gi\|1... gi\|16120652, gi\|... - gi\|218927520\|ref\|YP_002345395.1\| LexA repressor [Yersinia pestis CO92], gi\|16120652\|ref\|NP_403965.1\|... gi\|165990491, gi... - gi\|166010401\|ref\|ZP_02231299.1\| LexA repressor [Yersinia pestis biovar Antiqua str. E1979001], gi\|16... gi\|167418922, gi... - gi\|167418922\|ref\|ZP_02310675.1\| LexA repressor [Yersinia pestis biovar Orientalis str. MG05-1020], g... gi\|167402457, gi... - gi\|167402457\|ref\|ZP_02307914.1\| LexA repressor [Yersinia pestis biovar Antiqua str. UG05-0454], gi\|1... gi\|167467145 - gi\|167467145\|ref\|ZP_02331849.1\| LexA repressor [Yersinia pestis FV-1] gi\|167426198, gi... - gi\|167426198\|ref\|ZP_02317951.1\| LexA repressor [Yersinia pestis biovar Mediaevalis str. K1973002], g... LEXA_YERPB - LexA repressor OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=lexA PE=3 SV=1 LEXA_YERPY - LexA repressor OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=lexA PE=3 SV=1	6.0E-58	[1..202]	[1..202]
gi\|77961099, gi\|... - gi\|77961099\|ref\|ZP_00824946.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|238764118, gi... - gi\|238764118\|ref\|ZP_04625072.1\| LexA repressor [Yersinia kristensenii ATCC 33638], gi\|238697655\|gb\|E...	1.0E-57	[1..202]	[1..202]
LEXA_YERE8 - LexA repressor OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) GN=le... gi\|238716119, gi... - gi\|77957500\|ref\|ZP_00821554.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|238701485, gi... - gi\|238760283\|ref\|ZP_04621426.1\| LexA repressor [Yersinia aldovae ATCC 35236], gi\|238701485\|gb\|EEP940...	3.0E-57	[1..202]	[1..202]
gi\|77977114, gi\|... - gi\|77977114\|ref\|ZP_00832572.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop...	3.0E-57	[1..202]	[1..202]
gi\|238789914, gi... - gi\|77972801\|ref\|ZP_00828358.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop...	7.0E-57	[1..202]	[1..202]

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Predicted Domain #1

Region A:
Residues: [1-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALTARQQE VFDLIRDHIS QTGMPPTRAE IAQRLGFRSP NAAEEHLKAL ARKGVLEIVS  60
   61 GASRGIRLLQ EEEDGLPLVG RVAAGEPLLA QQHIEGHYQV DPSLFKPSAD FLLRVSGMSM 120
  121 KDIGIMDGDL LAVHKTQDVR NGQVVVARID DEVTVKRLKK QGNKVELLPE NSEFTPIVVD 180
  181 LREQSFTIEG LAVGVIRNGE WL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.154902
Match:	1jhhA
Description:	LexA repressor, N-terminal DNA-binding domain; LexA C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.30784351115827	bayes_pls_golite062009
nucleic acid binding	0.603302373860066	bayes_pls_golite062009
DNA binding	0.452668330421957	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
binding	0.355412070907203	bayes_pls_golite062009
transcription factor activity	0.0554645717043947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: