YRC Public Data Repository - Protein Structure Prediction

Protein:	EG11072
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	456 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG11072.

Description	E-value	Query Range	Subject Range
EX7L_SHISS - Exodeoxyribonuclease 7 large subunit OS=Shigella sonnei (strain Ss046) GN=xseA PE=3 SV=1 gi\|192958322, gi... - gi\|75237745\|ref\|ZP_00721761.1\| COG1570: Exonuclease VII, large subunit [Escherichia coli E110019], g... gi\|75229159, gi\|... - gi\|75229159\|ref\|ZP_00715731.1\| COG1570: Exonuclease VII, large subunit [Escherichia coli B7A], gi\|19... EX7L_SHIB3 - Exodeoxyribonuclease 7 large subunit OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=... EX7L_ECO8A - Exodeoxyribonuclease 7 large subunit OS=Escherichia coli O8 (strain IAI1) GN=xseA PE=3 SV=1 EX7L_ECO55 - Exodeoxyribonuclease 7 large subunit OS=Escherichia coli (strain 55989 / EAEC) GN=xseA PE=3 SV=1	584.0	[0..1]	[456..1]
gi\|124498698, gi... - gi\|124531252\|ref\|ZP_01701594.1\| exodeoxyribonuclease VII, large subunit [Escherichia coli B], gi\|124... EX7L_ECOHS - Exodeoxyribonuclease 7 large subunit OS=Escherichia coli O9:H4 (strain HS) GN=xseA PE=3 SV=1 EX7L_ECOLC - Exodeoxyribonuclease 7 large subunit OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=x...	584.0	[0..1]	[456..1]
gi\|188491415, gi... - gi\|75515849\|ref\|ZP_00737984.1\| COG1570: Exonuclease VII, large subunit [Escherichia coli 53638], gi\|...	583.0	[0..1]	[456..1]
EX7L_SHIF8 - Exodeoxyribonuclease 7 large subunit OS=Shigella flexneri serotype 5b (strain 8401) GN=xseA PE=3 SV=...	583.0	[0..1]	[456..1]
gi\|192927633, gi... - gi\|75257316\|ref\|ZP_00728840.1\| COG1570: Exonuclease VII, large subunit [Escherichia coli E22], gi\|19... gi\|194414600, gi... - gi\|75211475\|ref\|ZP_00711565.1\| COG1570: Exonuclease VII, large subunit [Escherichia coli B171], gi\|1...	581.0	[0..1]	[456..1]
gi\|148275 - gi\|148275\|gb\|AAA24766.1\| exonuclease VII large subunit [Escherichia coli]	581.0	[0..1]	[456..1]
EX7L_SHIBS - Exodeoxyribonuclease 7 large subunit OS=Shigella boydii serotype 4 (strain Sb227) GN=xseA PE=3 SV=1	580.0	[0..1]	[456..1]
gi\|83570729, gi\|... - gi\|83570729\|ref\|ZP_00922172.1\| COG1570: Exonuclease VII, large subunit [Shigella dysenteriae 1012], ...	580.0	[0..1]	[456..1]
gi\|30042156, gi\|... - gi\|30063901\|ref\|NP_838072.1\| exodeoxyribonuclease VII large subunit [Shigella flexneri 2a str. 2457T... EX7L_SHIFL - Exodeoxyribonuclease 7 large subunit OS=Shigella flexneri GN=xseA PE=3 SV=4 gi\|56383673, gi\|... - gi\|56480122\|ref\|NP_708348.2\| exodeoxyribonuclease VII large subunit [Shigella flexneri 2a str. 301],...	580.0	[0..1]	[456..1]
gi\|167991817, gi... - gi\|205329864\|gb\|EDZ16628.1\| exodeoxyribonuclease VII, large subunit [Salmonella enterica subsp. ente... EX7L_SALTY - Exodeoxyribonuclease 7 large subunit OS=Salmonella typhimurium GN=xseA PE=3 SV=1 EX7L_SALTY - Exodeoxyribonuclease 7 large subunit OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)... EX7L_SALTY - Exodeoxyribonuclease 7 large subunit OS=Salmonella typhimurium GN=xseA PE=3 SV=1 gi\|197240351, gi... - gi\|197262096\|ref\|ZP_03162170.1\| exodeoxyribonuclease VII, large subunit [Salmonella enterica subsp. ... lcl\|NC_016856.1_... - [gene=xseA] [protein=exodeoxyribonuclease VII large subunit] [protein_id=YP_005238605.1] [location=2...	577.0	[0..1]	[447..1]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPSQSPAIF TVSRLNQTVR LLLEHEMGQV WISGEISNFT QPASGHWYFT LKDDTAQVRC  60
   61 AMFRNSNRRV TFRPQHGQQV LVRANITLYE PRGDYQIIVE SMQP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	13.552842
Match:	PF01336.16
Description:	No description for PF01336.16 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.484	0.236	DNA catabolic process	a.1.1	Globin-like
View	Download	0.428	0.163	DNA catabolic process	b.60.1	Lipocalins
View	Download	0.516	0.018	DNA catabolic process	b.61.1	Avidin/streptavidin
View	Download	0.509	0.014	DNA catabolic process	b.8.1	TRAF domain-like
View	Download	0.450	N/A	N/A	a.1.1	Globin-like

Predicted Domain #2

Region A:
Residues: [105-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGEGLLQQKY EQLKAKLQAE GLFDQQYKKP LPSPAHCVGV ITSKTGAALH DILHVLKRRD  60
   61 PSLPVIIYPA AVQGDDAPGQ IVRAIELANQ R

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.585	d.58.17	Metal-binding domain
View	Download	0.593	d.58.4	Dimeric alpha+beta barrel
View	Download	0.553	c.5.1	MurCD N-terminal domain
View	Download	0.697	c.58.1	Aminoacid dehydrogenase-like, N-terminal domain
View	Download	0.555	c.58.1	Aminoacid dehydrogenase-like, N-terminal domain

Predicted Domain #3

Region A:
Residues: [196-396]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NECDVLIVGR GGGSLEDLWS FNDERVARAI FTSRIPVVSA VGHETDVTIA DFVADLRAPT  60
   61 PSAAAEVVSR NQQELLRQVQ STRQRLEMAM DYYLANRTRR FTQIHHRLQQ QHPQLRLARQ 120
  121 QTMLERLQKR MSFALENQLK RTGQQQQRLT QRLNQQNPQP KIHRAQTRIQ QLEYRLAETL 180
  181 RAQLSATRER FGNAVTHLEA V

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	104.443697
Match:	PF02601.6
Description:	No description for PF02601.6 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [397-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPLSTLARGY SVTTATDGNV LKKVKQVKAG EMLTTRLEDG WIESEVKNIQ PVKKSRKKVH  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits