YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|17427958
Organism:	Ralstonia solanacearum
Length:	167 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|17427958.

Description	E-value	Query Range	Subject Range
gi\|83727479, gi\|... - gi\|83745789\|ref\|ZP_00942846.1\| Dihydrofolate reductase [Ralstonia solanacearum UW551], gi\|83727479\|g... gi\|207743703, gi... - gi\|207743703\|ref\|YP_002260095.1\| dihydrofolate reductase protein [Ralstonia solanacearum IPO1609], g... gi\|206590567, gi... - gi\|207725331\|ref\|YP_002255727.1\| dihydrofolate reductase protein [Ralstonia solanacearum MolK2], gi\|...	235.0	[0..1]	[167..1]
DYR_BACSU - Dihydrofolate reductase OS=Bacillus subtilis (strain 168) GN=dfrA PE=1 SV=2 DYR_BACSU - Dihydrofolate reductase OS=Bacillus subtilis GN=dfrA PE=1 SV=2 gi\|221323614 - gi\|221323614\|ref\|ZP_03604908.1\| dihydrofolate reductase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221319339 - gi\|221319339\|ref\|ZP_03600633.1\| dihydrofolate reductase [Bacillus subtilis subsp. subtilis str. JH64... gi\|221314416 - gi\|221314416\|ref\|ZP_03596221.1\| dihydrofolate reductase [Bacillus subtilis subsp. subtilis str. NCIB...	234.0	[0..3]	[166..1]
gi\|143742, gi\|66101 - pir\|\|RDBSD dihydrofolate reductase (EC 1.5.1.3) - Bacillus subtilis, gi\|143742\|gb\|AAA22853.1\| dihyd...	234.0	[0..3]	[166..1]
gi\|72118030, gi\|... - gi\|73540617\|ref\|YP_295137.1\| dihydrofolate reductase [Ralstonia eutropha JMP134], gi\|72118030\|gb\|AAZ...	228.0	[0..1]	[167..1]
gi\|113868662, gi... - gi\|113868662\|ref\|YP_727151.1\| dihydrofolate reductase [Ralstonia eutropha H16], gi\|113527438\|emb\|CAJ...	227.0	[0..1]	[166..1]
gi\|93355357, gi\|... - gi\|94311505\|ref\|YP_584715.1\| dihydrofolate reductase [Ralstonia metallidurans CH34], gi\|93355357\|gb\|...	225.0	[0..1]	[167..1]
gi\|469211 - gi\|469211\|dbj\|BAA05974.1\| fusion protein, composed of HCV p21 (NS2), E.coli dihydroforate reductase,...	220.0	[0..3]	[161..304]
gi\|89100588, gi\|... - gi\|89100588\|ref\|ZP_01173447.1\| dihydrofolate reductase [Bacillus sp. NRRL B-14911], gi\|89084692\|gb\|E...	219.0	[0..3]	[163..1]
gi\|115421601, gi... - gi\|187477015\|ref\|YP_785039.1\| dihydrofolate reductase [Bordetella avium 197N], gi\|115421601\|emb\|CAJ4...	217.0	[0..1]	[163..1]
gi\|67735918, gi\|... - gi\|67735918\|ref\|ZP_00486852.1\| COG0262: Dihydrofolate reductase [Burkholderia pseudomallei 668], gi\|...	216.0	[0..1]	[163..1]

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Predicted Domain #1

Region A:
Residues: [1-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLLTLIVAR ARNGVIGRDN TLPWRLPEDL AHFKRTTMGA PIVMGRKTYE SIGRPLPGRR  60
   61 NIVVTRSAKL ALPGCEIAHS LEDAQRLCIG VEQIFLIGGA QLYADALPSA DRLIVTEIDA 120
  121 DFEGDAHFPA PDPAVWHEVA RETHHAAAPN DFDYAFVTYE RPPSDEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.522879
Match:	1ddrA
Description:	Dihydrofolate reductase, prokaryotic type
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dihydrofolic acid binding	5.17709559620199	bayes_pls_golite062009
dihydrofolate reductase activity	4.66343252900911	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4.14137539326183	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors	3.88025481634404	bayes_pls_golite062009
catalytic activity	1.48020895637259	bayes_pls_golite062009
oxidoreductase activity	1.39855499164233	bayes_pls_golite062009
binding	0.732884967748275	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: