YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|20804383
Organism:	Plasmodium falciparum
Length:	281 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|20804383.

Description	E-value	Query Range	Subject Range
gi\|25286942 - pir\|\|F83728 phosphoribosylpyrophosphate amidotransferase purF [imported] - Bacillus halodurans (stra... gi\|10173244, gi\|... - gi\|15613193\|ref\|NP_241496.1\| amidophosphoribosyltransferase [Bacillus halodurans C-125], gi\|10173244...	167.0	[0..16]	[278..168]
gi\|89093848, gi\|... - gi\|89093848\|ref\|ZP_01166794.1\| orotate phosphoribosyltransferase [Oceanospirillum sp. MED92], gi\|890...	167.0	[0..64]	[280..1]
gi\|134052904, gi... - gi\|88945227\|ref\|ZP_01148441.1\| Amidophosphoribosyl transferase [Desulfotomaculum reducens MI-1], gi\|...	167.0	[0..16]	[278..175]
gi\|85711492, gi\|... - gi\|85711492\|ref\|ZP_01042550.1\| orotate phosphoribosyltransferase [Idiomarina baltica OS145], gi\|8569...	166.0	[0..64]	[280..1]
gi\|71674011, gi\|... - gi\|71674011\|ref\|ZP_00671759.1\| Amidophosphoribosyl transferase [Trichodesmium erythraeum IMS101], gi...	165.0	[0..16]	[278..185]
gi\|2624600, gi\|2... - gi\|2624600\|pdb\|1AO0\|D Chain D, Glutamine Phosphoribosylpyrophosphate (Prpp) Amidotransferase From B....	165.0	[0..16]	[280..158]
gi\|56686461, gi\|... - gi\|56751502\|ref\|YP_172203.1\| amidophosphoribosyltransferase [Synechococcus elongatus PCC 6301], gi\|5... gi\|974612, gi\|74... - gi\|974612\|gb\|AAA75107.1\| glutamine PRPP amidotransferase [Synechococcus sp.], pir\|\|S77612 amidophosp... PUR1_SYNE7 - Amidophosphoribosyltransferase OS=Synechococcus elongatus (strain PCC 7942) GN=purF PE=3 SV=1	165.0	[0..16]	[279..186]
PYRE_PSE14 - Orotate phosphoribosyltransferase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)...	163.0	[0..64]	[280..1]
gi\|52002344, gi\|... - gi\|52079133\|ref\|YP_077924.1\| amidophosphoribosyltransferase [Bacillus licheniformis ATCC 14580], gi\|...	163.0	[0..16]	[280..169]

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Predicted Domain #1

Region A:
Residues: [1-281]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTIKENEFL CDEEIYKSFV HLKDKICEER KKKELVNNNI DNVNFNDDDD NNYDDDGNSY  60
   61 SSYIKEMKKL LKVVLLKYKA LKFGEFILKS KRKSNYFFSS GVLNNIVSSN IICFLLSELI 120
  121 LKNKLSFDYL LGASYKGIPM VSLTSHFLFE SKKYSNIFYL YDRKEKKEYG DKNVIVGNLD 180
  181 DDDKDILNLK KKTKNNQDEE KKNIIIIDDV FTCGTALTEI LAKLKTYEHL KVVAFIVLLN 240
  241 RNEYEINENN QKIYFKDIFE KRVGIPLYSI LSYKDDIQSM I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.09691
Match:	1lh0A
Description:	Orotate PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	3.1748712918814	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	3.0470646511978	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	2.97347277288245	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.21367942706564	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	2.02298774328915	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
purine binding	1.24786927434743	bayes_pls_golite062009
amidophosphoribosyltransferase activity	0.932396739123353	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
binding	0.535390228935555	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: