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View Structure Prediction Details

Protein: gi|7436675, gi|3...
Organism: Arabidopsis thaliana
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7436675, gi|3....

Description E-value Query
Range
Subject
Range
HMGCL_ARATH - Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Arabidopsis thaliana GN=HMGCL PE=1 SV=2
407.0 [0..1] [433..36]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLEEPLSF DKLPSMSTMD RIQRFSSGAC RPRDDVGMGH RWIEGRDCTT SNSCIDDDKS  60
   61 FAKESFPWRR HTRKLSEGEH MFRNISFAGR TSTVSGTLRE SKSFKEQKYS TFSNENGTSH 120
  121 ISNK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [125-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISKGIPKFVK IVEVGPRDGL QNEKNIVPTS VKVELIQRLV SSGLPVVEAT SFVSPKWVPQ  60
   61 LADAKDVMDA VNTLDGARLP VLTPNLKGFQ AAVSAGAKEV AIFASASESF SLSNINCTIE 120
  121 ESLLRYRVVA TAAKEHSVPV RGYVSCVVGC PVEGPVLPSK VAYVVKELYD MGCFEISLGD 180
  181 TIGIGTPGSV VPMLEAVMAV VPADKLAVHF HDTYGQALAN ILVSLQMGIS IVDSSIAGLG 240
  241 GCPYAKGASG NVATEDVVYM LNGLGVHTNV DLGKLIAAGD FISKHLGRPN GSKAAVALNR 300
  301 RITADASKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.522879
Match: 2cw6A
Description: Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle