YRC Public Data Repository - Protein Structure Prediction

Protein:	EIF3E_ARATH
Organism:	Arabidopsis thaliana
Length:	441 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EIF3E_ARATH.

Description	E-value	Query Range	Subject Range
EIF3E_XENTR - Eukaryotic translation initiation factor 3 subunit E OS=Xenopus tropicalis GN=eif3e PE=2 SV=1	348.0	[0..5]	[440..1]
EI3EB_XENLA - Eukaryotic translation initiation factor 3 subunit E-B OS=Xenopus laevis GN=eif3e-b PE=2 SV=1	348.0	[0..5]	[440..1]
gi\|7689381 - gi\|7689381\|gb\|AAF67757.1\|AF255679_1 eIF3e [Arabidopsis thaliana]	346.0	[0..1]	[441..1]
gi\|149721734 - gi\|149721734\|ref\|XP_001495193.1\| PREDICTED: similar to Eukaryotic translation initiation factor 3 su... gi\|73974299 - gi\|73974299\|ref\|XP_532304.2\| PREDICTED: similar to eukaryotic translation initiation factor 3, subun... gi\|109087237, gi... - gi\|109087239\|ref\|XP_001090593.1\| PREDICTED: eukaryotic translation initiation factor 3, subunit 6 48... gi\|123997605, gi... - gi\|61363628\|gb\|AAX42420.1\| eukaryotic translation initiation factor 3 subunit 6 48kDa [synthetic con... EIF3E_MACFA - Eukaryotic translation initiation factor 3 subunit E OS=Macaca fascicularis GN=EIF3E PE=2 SV=1 EIF3E_PONAB - Eukaryotic translation initiation factor 3 subunit E OS=Pongo abelii GN=EIF3E PE=2 SV=2 ENSOCUP00000006956 - pep:novel chromosome:oryCun2:3:123577974:123623555:-1 gene:ENSOCUG00000008050 transcript:ENSOCUT0000... EIF3E - eukaryotic translation initiation factor 3, subunit E IF36_PONPY - Eukaryotic translation initiation factor 3 subunit 6 - Pongo pygmaeus (Orangutan) EIF3E_MOUSE - Eukaryotic translation initiation factor 3 subunit E OS=Mus musculus GN=Eif3e PE=1 SV=1 EIF3E_RAT - Eukaryotic translation initiation factor 3 subunit E OS=Rattus norvegicus GN=Eif3e PE=2 SV=1 ENSCJAT00000012664 - null tr\|M3W0R4\|M3W0R4... - Eukaryotic translation initiation factor 3 subunit E OS=Felis catus GN=EIF3E PE=3 SV=1	344.0	[0..5]	[440..1]
EIF3E_BOVIN - Eukaryotic translation initiation factor 3 subunit E OS=Bos taurus GN=EIF3E PE=2 SV=1	344.0	[0..5]	[440..1]
gi\|61365190, gi\|... - gi\|61365190\|gb\|AAX42668.1\| eukaryotic translation initiation factor 3 subunit 6 [synthetic construct...	344.0	[0..5]	[440..1]
EIF3E_CHICK - Eukaryotic translation initiation factor 3 subunit E OS=Gallus gallus GN=EIF3E PE=2 SV=1	344.0	[0..5]	[437..1]

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Predicted Domain #1

Region A:
Residues: [1-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEESKQNYDL TPLIAPNLDR HLVFPIFEFL QERQLYPDEQ ILKSKIQLLN QTNMVDYAMD  60
   61 IHKSLYHTED APQEMVERRT EVVARLKSLE EAAAPLVSFL LNPNAVQELR ADKQYNLQML 120
  121 KERYQI

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	80.958607
Match:	PF09440.1
Description:	No description for PF09440.1 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [127-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPDQIEALYQ YAKFQFECGN YSGAADYLYQ YRTLCSNLER SLSALWGKLA SEILMQNWDI  60
   61 ALEELNRLKE IIDSKSFSSP LNQVQNRIWL MHWGLYIFF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.986	N/A	N/A	a.71.1	Endoplasmic reticulum protein ERP29, C-domain

Predicted Domain #3

Region A:
Residues: [226-330]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHDNGRTQII DLFNQDKYLN AIQTSAPHLL RYLATAFIVN KRRRPQLKEF IKVIQQEHYS  60
   61 YKDPIIEFLA CVFVNYDFDG AQKKMKECEE VIVNDPFLGK RVEDG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.888	a.118.8	TPR-like

Predicted Domain #4

Region A:
Residues: [331-441]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFSTVPLRDE FLENARLFVF ETYCKIHQRI DMGVLAEKLN LNYEEAERWI VNLIRTSKLD  60
   61 AKIDSESGTV IMEPTQPNVH EQLINHTKGL SGRTYKLVNQ LLEHTQAQAT R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.39794
Match:	1ufmA
Description:	Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits