YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|226839585, gi...
Organism:	Escherichia sp. 1_1_43
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|226839585, gi....

Description	E-value	Query Range	Subject Range
gi\|83587691 - gi\|83587691\|ref\|ZP_00926318.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli 101-1] gi\|42943 - gi\|42943\|emb\|CAA47309.1\| unnamed protein product [Escherichia coli] gi\|75178806 - gi\|75178806\|ref\|ZP_00698842.1\| COG0120: Ribose 5-phosphate isomerase [Shigella boydii BS512] gi\|75187629 - gi\|75187629\|ref\|ZP_00700896.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E24377A] RPIA_ECOK1 - Ribose-5-phosphate isomerase A OS=Escherichia coli O1:K1 / APEC GN=rpiA PE=3 SV=1 gi\|75196865 - gi\|75196865\|ref\|ZP_00706935.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli HS] gi\|124526181, gi... - gi\|124526181\|ref\|ZP_01698186.1\| ribose 5-phosphate isomerase [Escherichia coli B], gi\|124502285\|gb\|E... gi\|227888463, gi... - gi\|227888463\|ref\|ZP_04006268.1\| ribose-5-phosphate isomerase A [Escherichia coli 83972], gi\|22783473... gi\|75212472 - gi\|75212472\|ref\|ZP_00712496.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli B171] gi\|75228581 - gi\|75228581\|ref\|ZP_00715210.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli B7A] gi\|75239518 - gi\|75239518\|ref\|ZP_00723489.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E110019] gi\|75258513 - gi\|75258513\|ref\|ZP_00729935.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E22]	293.0	[0..13]	[243..1]
gi\|75241290 - gi\|75241290\|ref\|ZP_00725152.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli F11]	291.0	[0..13]	[243..1]
gi\|75515302 - gi\|75515302\|ref\|ZP_00737486.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli 53638]	290.0	[0..13]	[243..1]
RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea GN=rpiA PE=3 SV=1 RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=rpiA PE=...	285.0	[0..25]	[242..1]
gi\|114308819, gi... - gi\|71550684\|ref\|ZP_00670776.1\| Ribose 5-phosphate isomerase [Nitrosomonas eutropha C71], gi\|71484115...	284.0	[0..24]	[242..22]
gi\|208808380, gi... - gi\|208808380\|ref\|ZP_03250717.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4206... gi\|195936532 - gi\|195936532\|ref\|ZP_03081914.1\| ribose-5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4024... gi\|194424196, gi... - gi\|194436714\|ref\|ZP_03068814.1\| ribose 5-phosphate isomerase A [Escherichia coli 101-1], gi\|19442419... gi\|194415547, gi... - gi\|194426239\|ref\|ZP_03058794.1\| ribose 5-phosphate isomerase A [Escherichia coli B171], gi\|194415547... RPIA_ECOSE - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain SE11) GN=rpiA PE=3 SV=1 RPIA_ECO5E - Ribose-5-phosphate isomerase A OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=rpiA PE=3 SV=1 gi\|208819067, gi... - gi\|208819067\|ref\|ZP_03259387.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4042... gi\|208813802, gi... - gi\|208813802\|ref\|ZP_03255131.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4045... RPIA_ECOSM - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=rpiA PE=3 SV=1 RPIA_ECODH - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain K12 / DH10B) GN=rpiA PE=3 SV=1 gi\|189379720, gi... - gi\|189379720\|gb\|EDU98136.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC508], gi... gi\|189373917, gi... - gi\|189373917\|gb\|EDU92333.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC869], gi... gi\|193067384, gi... - gi\|193067384\|ref\|ZP_03048352.1\| ribose 5-phosphate isomerase A [Escherichia coli E110019], gi\|192959... gi\|193063514, gi... - gi\|193063514\|ref\|ZP_03044603.1\| ribose 5-phosphate isomerase A [Escherichia coli E22], gi\|192930791\|... gi\|191168214, gi... - gi\|191168214\|ref\|ZP_03030009.1\| ribose 5-phosphate isomerase A [Escherichia coli B7A], gi\|190901756\|... RPIA_SHIB3 - Ribose-5-phosphate isomerase A OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=rpiA P... RPIA_ECOLI - Ribose-5-phosphate isomerase A (EC 5.3.1.6) (Phosphoriboisomerase A) (PRI) - Escherichia coli RPIA_ECO45 - Ribose-5-phosphate isomerase A OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=rpiA PE=3 SV=1 RPIA_ECO8A - Ribose-5-phosphate isomerase A OS=Escherichia coli O8 (strain IAI1) GN=rpiA PE=3 SV=1 gi\|217319466, gi... - gi\|217327099\|ref\|ZP_03443182.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. TW1458... RPIA_ECO27 - Ribose-5-phosphate isomerase A OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=rpiA PE=3 SV=... RPIA_ECOLU - Ribose-5-phosphate isomerase A OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=rpiA PE=3 ... RPIA_ECO7I - Ribose-5-phosphate isomerase A OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=rpiA PE=3 SV=1 RPIA_ECO55 - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain 55989 / EAEC) GN=rpiA PE=3 SV=1 RPIA_ECO81 - Ribose-5-phosphate isomerase A OS=Escherichia coli O81 (strain ED1a) GN=rpiA PE=3 SV=1 EG11443 - ribose 5-phosphate isomerase, constitutive / Ribose-5-phosphate isomerase A, alkali-inducible sp\|B7UHW1\|RPIA_ECO27 - Ribose-5-phosphate isomerase A OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=rpiA PE=3 SV=... RPIA_ECOLC - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=rpiA PE... gi\|168753856, gi... - gi\|189358712\|gb\|EDU77131.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4401], g... gi\|168747603, gi... - gi\|188017814\|gb\|EDU55936.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4113], g... gi\|189000540, gi... - gi\|189000540\|gb\|EDU69526.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4076], g... gi\|168773456, gi... - gi\|187770763\|gb\|EDU34607.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4196], g... gi\|168766911, gi... - gi\|189363891\|gb\|EDU82310.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4486], g... gi\|242378444, gi... - gi\|251786171\|ref\|YP_003000475.1\| hypothetical protein B21_02708 [Escherichia coli BL21], gi\|24237844... gi\|189369231, gi... - gi\|189369231\|gb\|EDU87647.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4501], g... RPIA_ECOBW - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=rpiA PE=3 SV=1 gi\|254162825, gi... - gi\|254162825\|ref\|YP_003045933.1\| ribose-5-phosphate isomerase A [Escherichia coli B str. REL606], gi... gi\|253978892, gi... - gi\|254289585\|ref\|YP_003055333.1\| ribose-5-phosphate isomerase A [Escherichia coli BL21(DE3)], gi\|253... gi\|254594263, gi... - gi\|254794863\|ref\|YP_003079700.1\| ribose 5-phosphate isomerase, constitutive [Escherichia coli O157:H... RPIA_ECOL6 - Ribose-5-phosphate isomerase A OS=Escherichia coli O6 GN=rpiA PE=3 SV=1 gi\|56383751, gi\|... - gi\|56480200\|ref\|NP_708676.2\| ribose-5-phosphate isomerase A [Shigella flexneri 2a str. 301], gi\|5638... RPIA_SHIBS - Ribose-5-phosphate isomerase A OS=Shigella boydii serotype 4 (strain Sb227) GN=rpiA PE=3 SV=1 gi\|85675725, gi\|... - gi\|89109692\|ref\|AP_003472.1\| ribosephosphate isomerase, constitutive [Escherichia coli str. K-12 sub... gi\|13363257, gi\|... - gi\|15833039\|ref\|NP_311812.1\| ribose-5-phosphate isomerase A [Escherichia coli O157:H7 str. Sakai], g... RPIA_SHIF8 - Ribose-5-phosphate isomerase A OS=Shigella flexneri serotype 5b (strain 8401) GN=rpiA PE=3 SV=1 RPIA_SHISS - Ribose-5-phosphate isomerase A OS=Shigella sonnei (strain Ss046) GN=rpiA PE=3 SV=1 RPIA_SHIDS - Ribose-5-phosphate isomerase A OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=rpiA PE=3 SV=1 RPIA_ECOL6 - Ribose-5-phosphate isomerase A OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=rpi... RPIA_SHIFL - Ribose-5-phosphate isomerase A OS=Shigella flexneri GN=rpiA PE=3 SV=1 gi\|30064224, gi\|... - gi\|30064224\|ref\|NP_838395.1\| ribose-5-phosphate isomerase A [Shigella flexneri 2a str. 2457T], gi\|30... RPIA_ECO57 - Ribose-5-phosphate isomerase A OS=Escherichia coli O157:H7 GN=rpiA PE=3 SV=1 EG11443 - ribose 5-phosphate isomerase, constitutive / Ribose-5-phosphate isomerase A, alkali-inducible gi\|12517444, gi\|... - gi\|15803449\|ref\|NP_289482.1\| ribose-5-phosphate isomerase A [Escherichia coli O157:H7 EDL933], gi\|12... RPIA_ECOHS - Ribose-5-phosphate isomerase A OS=Escherichia coli O9:H4 (strain HS) GN=rpiA PE=3 SV=1 RPIA_ECO24 - Ribose-5-phosphate isomerase A OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=rpiA PE=3 SV=...	284.0	[0..25]	[243..1]
lcl\|NC_016856.1_... - [gene=rpiA] [protein=ribose-5-phosphate isomerase A] [protein_id=YP_005239204.1] [location=complemen... RPIA_SALPB - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=rpiA PE=3 ... gi\|213646130 - gi\|213646130\|ref\|ZP_03376183.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|213864991 - gi\|213864991\|ref\|ZP_03387110.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|214003525 - gi\|214003525\|ref\|ZP_03414260.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... RPIA_SALPC - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi C (strain RKS4594) GN=rpiA PE=3 SV=1 RPIA_SALEP - Ribose-5-phosphate isomerase A OS=Salmonella enteritidis PT4 (strain P125109) GN=rpiA PE=3 SV=1 RPIA_SALTI - Ribose-5-phosphate isomerase A OS=Salmonella typhi GN=rpiA PE=3 SV=1 gi\|213162872 - gi\|213162872\|ref\|ZP_03348582.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|213427298 - gi\|213427298\|ref\|ZP_03360048.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|213613186 - gi\|213613186\|ref\|ZP_03371012.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|16761844 - gi\|16761844\|ref\|NP_457461.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ser... gi\|238909863 - gi\|238909863\|ref\|ZP_04653700.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... RPIA_SALTY - Ribose-5-phosphate isomerase A OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=rp... RPIA_SALPK - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi A (strain AKU_12601) GN=rpiA PE=3 SV=1 gi\|29143331, gi\|... - gi\|29143331\|ref\|NP_806673.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ser... RPIA_SALG2 - Ribose-5-phosphate isomerase A OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=rpiA PE=3 SV... RPIA_SALCH - Ribose-5-phosphate isomerase A OS=Salmonella choleraesuis (strain SC-B67) GN=rpiA PE=3 SV=1 RPIA_SALPA - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=rpiA PE=3 SV... RPIA_SALTY - Ribose-5-phosphate isomerase A OS=Salmonella typhimurium GN=rpiA PE=3 SV=1 RPIA_SALCH - Ribose-5-phosphate isomerase A OS=Salmonella choleraesuis GN=rpiA PE=3 SV=1 RPIA_SALPA - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi A GN=rpiA PE=3 SV=1 RPIA_SALTI - Ribose-5-phosphate isomerase A OS=Salmonella typhi GN=rpiA PE=3 SV=1 RPIA_SALPB - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=rpiA PE=3 ... RPIA_SALTY - Ribose-5-phosphate isomerase A OS=Salmonella typhimurium GN=rpiA PE=3 SV=1 RPIA_SALCH - Ribose-5-phosphate isomerase A OS=Salmonella choleraesuis GN=rpiA PE=3 SV=1	283.0	[0..25]	[243..1]
RPIA_ERWCT - Ribose-5-phosphate isomerase A OS=Erwinia carotovora subsp. atroseptica GN=rpiA PE=3 SV=1 RPIA_PECAS - Ribose-5-phosphate isomerase A OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=r...	282.0	[0..25]	[243..1]
RPIA_EDWIC - Ribose-5-phosphate isomerase A OS=Edwardsiella ictaluri GN=rpiA PE=3 SV=1 RPIA_EDWI9 - Ribose-5-phosphate isomerase A OS=Edwardsiella ictaluri (strain 93-146) GN=rpiA PE=3 SV=1	282.0	[0..25]	[242..1]
RPIA_SHESW - Ribose-5-phosphate isomerase A OS=Shewanella sp. (strain W3-18-1) GN=rpiA PE=3 SV=1	282.0	[0..25]	[242..1]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTGSESLFL YIMRVKFHTT GETIMTQDEL KKAVGWAALQ YVQPGTIVGV GTGSTAAHFI  60
   61 DALGTMKGQI EGAVSSSDAS TEKLKSLGIH VFDLNEVDSL GIYVDGADEI NGHMQMIKGG 120
  121 GAALTREKII ASVAEKFICI ADASKQVDIL GKFPLPVEVI PMARSAVARQ LVKLGGRPEY 180
  181 RQGVVTDNGN VILDVHGMEI LDPIAMENAI NAIPGVVTVG LFANRGADVA LIGTPDGVKT 240
  241 IVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.69897
Match:	1ks2A
Description:	D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribose-5-phosphate isomerase activity	2.23318567990318	bayes_pls_golite062009
6-phosphogluconolactonase activity	1.97756803122763	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.61058174487002	bayes_pls_golite062009
catalytic activity	0.424959044318554	bayes_pls_golite062009
nucleic acid binding	0.281224782944976	bayes_pls_golite062009
binding	0.228090098582514	bayes_pls_golite062009
glucosamine-6-phosphate deaminase activity	0.111185777194415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.075853172283603	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: