YRC Public Data Repository - Protein Structure Prediction

Protein:	CLPP_VIBCM
Organism:	Vibrio cholerae M66-2
Length:	200 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLPP_VIBCM.

Description	E-value	Query Range	Subject Range
gi\|90579278, gi\|... - gi\|90579278\|ref\|ZP_01235088.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio angustum S14],... gi\|89073230, gi\|... - gi\|89073230\|ref\|ZP_01159760.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium sp. SK...	280.0	[0..1]	[198..9]
CLPP_THIDA - ATP-dependent Clp protease proteolytic subunit OS=Thiobacillus denitrificans (strain ATCC 25259) GN=...	278.0	[0..3]	[200..12]
gi\|121727845, gi... - gi\|75814907\|ref\|ZP_00745448.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Vibrio chol... gi\|229511781, gi... - gi\|229511781\|ref\|ZP_04401260.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae B33]... gi\|229507982, gi... - gi\|229507982\|ref\|ZP_04397487.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae BX 3... gi\|229518918, gi... - gi\|229518918\|ref\|ZP_04408361.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae RC9]... gi\|229515308, gi... - gi\|229515308\|ref\|ZP_04404768.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae TMA ... gi\|229529052, gi... - gi\|229529052\|ref\|ZP_04418442.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae 1212... gi\|229337523, gi... - gi\|229523942\|ref\|ZP_04413347.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae bv. ... gi\|229607528, gi... - gi\|229607528\|ref\|YP_002878176.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio cholerae MJ-... gi\|254844715, gi... - gi\|75830738\|ref\|ZP_00760010.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Vibrio chol... gi\|116214947, gi... - gi\|75821589\|ref\|ZP_00751429.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Vibrio chol... gi\|75827244 - gi\|75827244\|ref\|ZP_00756679.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Vibrio chol... tr\|D7H9Y6\|D7H9Y6... - ATP-dependent Clp protease proteolytic subunit OS=Vibrio cholerae GN=clpP PE=3 SV=1, ATP-dependent C...	277.0	[0..1]	[200..9]
gi\|91187849, gi\|... - gi\|91228617\|ref\|ZP_01262535.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio alginolyticus ... gi\|75853478, gi\|... - gi\|75853478\|ref\|ZP_00761324.1\| COG0740: Protease subunit of ATP-dependent Clp proteases [Vibrio sp. ...	277.0	[0..1]	[200..9]
CLPP_PHOPR - ATP-dependent Clp protease proteolytic subunit OS=Photobacterium profundum GN=clpP PE=3 SV=2 CLPP_PHOPR - ATP-dependent Clp protease proteolytic subunit OS=Photobacterium profundum (strain SS9) GN=clpP PE=3...	277.0	[0..1]	[198..1]
CLPP_VIBTL - ATP-dependent Clp protease proteolytic subunit OS=Vibrio tasmaniensis (strain LGP32) GN=clpP PE=3 SV... gi\|84387735, gi\|... - gi\|84387735\|ref\|ZP_00990751.1\| ATP-dependent Clp protease proteolytic subunit [Vibrio splendidus 12B...	277.0	[0..1]	[198..9]
gi\|46914236, gi\|... - gi\|54309798\|ref\|YP_130818.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium profundu... gi\|27363512 - ref\|NP_759040.1\| ATP-dependent Clp protease, proteolytic subunit [Photobacterium profundum SS9]	277.0	[0..1]	[198..9]
CLPP_VIBPA - ATP-dependent Clp protease proteolytic subunit OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIM... CLPP_VIBPA - ATP-dependent Clp protease proteolytic subunit OS=Vibrio parahaemolyticus GN=clpP PE=3 SV=1	276.0	[0..1]	[198..1]
gi\|90410782, gi\|... - gi\|90410782\|ref\|ZP_01218797.1\| ATP-dependent Clp protease proteolytic subunit [Photobacterium profun...	276.0	[0..1]	[198..9]
CLPP_VIBVU - ATP-dependent Clp protease proteolytic subunit OS=Vibrio vulnificus (strain CMCP6) GN=clpP PE=3 SV=2 CLPP_VIBVY - ATP-dependent Clp protease proteolytic subunit OS=Vibrio vulnificus (strain YJ016) GN=clpP PE=3 SV=2 CLPP_VIBVU - ATP-dependent Clp protease proteolytic subunit OS=Vibrio vulnificus GN=clpP PE=3 SV=2	275.0	[0..1]	[199..1]

Back

Predicted Domain #1

Region A:
Residues: [1-200]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPIFDALVP MVVEQTSRGE RSYDIYSRLL KERVIFLTGQ VEDHMANLVV AQLLFLESEN  60
   61 PDKDIFLYIN SPGGSVTAGM SIYDTMQFIK PNVSTVCMGQ ACSMGAFLLA GGAPGKRYVL 120
  121 PNSRVMIHQP LGGFQGQASD IQIHAQEILT IKNKLNRLLA EHTGQPIEVI ERDTDRDNFM 180
  181 SADQAVEYGL VDAVLKHRGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.0
Match:	1tyfA
Description:	Clp protease, ClpP subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.46154163027498	bayes_pls_golite062009
CoA carboxylase activity	0.939626895227199	bayes_pls_golite062009
acetyl-CoA carboxylase activity	0.764444938444292	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.621229080200493	bayes_pls_golite062009
enoyl-CoA hydratase activity	0.620657548610719	bayes_pls_golite062009
hydrolase activity	0.534319520590169	bayes_pls_golite062009
binding	0.367666848528835	bayes_pls_golite062009
ligase activity	0.32092496884003	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: