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View Structure Prediction Details

Protein: ORP1C_ARATH
Organism: Arabidopsis thaliana
Length: 814 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORP1C_ARATH.

Description E-value Query
Range
Subject
Range
gi|42570131 - gi|42570131|ref|NP_849343.2| ORP1C (OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1C); oxysterol b...
809.0 [0..1] [814..1]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPFCCVTTV SDHSPSMPPL PEPQPPLPNY AADFGSARSE PIITRSASQS YNHSGQFNNN  60
   61 LIHSLSFNHH QSDVTDRLGQ RVLALPAAVR EPPVDVKIND I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGNGIAGILY KWVNYGRGWR PRWFVLQDGV LSYYKIHGPD KIFVSPETEK GSKVIGDESA  60
   61 RMISRHNRRG GSSSSCQLRR KPFGEVHLKV SSVRESRSDD KRFSIFTGTK RLHLRAETRE 120
  121 DRTTWVEALQ AVKDMFPRMS NSELMAPTNN LAMSTEKIRL RLIEEGVSEL AIQDCEQIMK 180
  181 SE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.522879
Match: 1u5fA
Description: Crystal Structure of the PH Domain of SKAP-Hom with 8 Vector-derived N-terminal Residues
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [284-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSALQSQLVL LKQKQWLLID TLRQLETEKV DLENTVVDES QRQADNGCSG ELRHEKFSEG  60
   61 TATESDDDNE RGDAAEEEFD EEENTFFDTR DFLSSSSFKS SGSGFRTSSF SSDEDGFESE 120
  121 DDIDPSIKSI GCNYPRVKRR KNLPD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [429-814]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVEKEKSVSL WSMIKDNIGK DLTKVCLPVY FNEPLSSLQK CFEDLEYSYL LDRAFEYGKR  60
   61 GNSLMRILNV AAFAVSGYAS TEGRICKPFN PLLGETYEAD YPDKGLRFFS EKVSHHPMVV 120
  121 ACHCDGTGWK FWGDSNLRSK FWGRSIQLDP VGVLTLQFDD GEILQWSKVT TSIYNLILGK 180
  181 LYCDHYGTMR IEGSAEYSCK LKFKEQSIID RNPHQVHGIV QNKSGKTVAT MFGKWDESIH 240
  241 FVTGDCSGKG KLSEDMSGAQ LLWKRSKPPG NATKYNLTRF AITLNELTPG LKERLPPTDS 300
  301 RLRPDQRYLE NGEFEMANTE KLRLEQRQRQ ARKMQERGWK PRWFMKEKGS ESYRYKGGYW 360
  361 EAREDGSWVD CPDIFGHIDS DQQMIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.522879
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sterol binding 3.12877992228795 bayes_pls_golite062009
steroid binding 2.54679035876403 bayes_pls_golite062009
binding 1.67154210149282 bayes_pls_golite062009
lipid binding 1.46539100663772 bayes_pls_golite062009
oxysterol binding 1.1738554488982 bayes_pls_golite062009
phospholipid binding 0.0867097353003303 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle