YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|225686252, gi...
Organism:	Brucella melitensis ATCC 23457
Length:	146 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|225686252, gi....

Description	E-value	Query Range	Subject Range
gi\|36959065, gi\|... - gi\|36959065\|gb\|AAQ87490.1\| Transcriptional regulator [Rhizobium sp. NGR234], gi\|227818810\|ref\|YP_002...	255.0	[0..1]	[145..1]
gi\|83836227, gi\|... - gi\|83952554\|ref\|ZP_00961285.1\| methionine sulfoxide reductase B [Roseovarius nubinhibens ISM], gi\|83...	254.0	[0..1]	[145..1]
gi\|150032007, gi... - gi\|150377460\|ref\|YP_001314055.1\| methionine sulfoxide reductase B [Sinorhizobium medicae WSM419], gi...	252.0	[0..1]	[145..1]
MSRB2_RHIME - Peptide methionine sulfoxide reductase MsrB 2 OS=Rhizobium meliloti (strain 1021) GN=msrB2 PE=3 SV=1 MSRB2_RHIME, MSB... - Peptide methionine sulfoxide reductase msrB 2 OS=Rhizobium meliloti GN=msrB2 PE=3 SV=1, (Q92Y46) Pep...	252.0	[0..1]	[145..1]
gi\|60494275, gi\|... - gi\|60682841\|ref\|YP_212985.1\| bifunctional methionine sulfoxide reductase A/B protein [Bacteroides fr...	248.0	[0..2]	[144..216]
gi\|189022934, gi... - gi\|189022934\|ref\|YP_001932675.1\| methionine sulfoxide reductase B [Brucella abortus S19], gi\|1890215... gi\|254698964 - gi\|254698964\|ref\|ZP_05160792.1\| methionine sulfoxide reductase B [Brucella abortus bv. 2 str. 86/8/5... gi\|254732412 - gi\|254732412\|ref\|ZP_05190990.1\| methionine sulfoxide reductase B [Brucella abortus bv. 4 str. 292] gi\|62197876, gi\|... - gi\|62317683\|ref\|YP_223536.1\| methionine sulfoxide reductase B [Brucella abortus bv. 1 str. 9-941], g... gi\|83269666 - gi\|83269666\|ref\|YP_418957.1\| methionine sulfoxide reductase B [Brucella melitensis biovar Abortus 23... gi\|82939940 - gi\|82939940\|emb\|CAJ12958.1\| Protein of unknown function DUF25 [Brucella melitensis biovar Abortus 23... gi\|254691181 - gi\|254691181\|ref\|ZP_05154435.1\| methionine sulfoxide reductase B [Brucella abortus bv. 6 str. 870] gi\|254695515 - gi\|254695515\|ref\|ZP_05157343.1\| methionine sulfoxide reductase B [Brucella abortus bv. 3 str. Tulya] gi\|237788042, gi... - gi\|237817229\|ref\|ZP_04596221.1\| methionine-R-sulfoxide reductase [Brucella abortus str. 2308 A], gi\|...	248.0	[0..1]	[146..1]
gi\|53714858, gi\|... - gi\|53714858\|ref\|YP_100850.1\| bifunctional methionine sulfoxide reductase A/B protein [Bacteroides fr...	247.0	[0..3]	[144..215]
gi\|29339811, gi\|... - gi\|29347909\|ref\|NP_811412.1\| bifunctional methionine sulfoxide reductase A/B protein [Bacteroides th...	246.0	[0..4]	[145..201]
gi\|225724305, gi... - gi\|225856354\|ref\|YP_002737865.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne... gi\|225722082, gi... - gi\|225858488\|ref\|YP_002739998.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne... gi\|66879653 - gi\|66879653\|ref\|ZP_00404670.1\| COG0225: Peptide methionine sulfoxide reductase [Streptococcus pneumo... gi\|25508388 - gi\|25508388\|pir\|\|A97944 peptide methionine sulfoxide reductase homolog [imported] - Streptococcus pn... gi\|183569878, gi... - gi\|183569878\|gb\|EDT90406.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pneumoni... gi\|15902621, gi\|... - gi\|15902621\|ref\|NP_358171.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococcus ... gi\|147765199, gi... - gi\|149010718\|ref\|ZP_01832089.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|183572966, gi... - gi\|183572966\|gb\|EDT93494.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pneumoni... gi\|147762715, gi... - gi\|149005775\|ref\|ZP_01829514.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|168492265, gi... - gi\|183573518\|gb\|EDT94046.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pneumoni... gi\|147928857, gi... - gi\|148992231\|ref\|ZP_01821954.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|168996394, gi... - gi\|169833892\|ref\|YP_001694133.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne... gi\|148989032, gi... - gi\|148989032\|ref\|ZP_01820432.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococc... gi\|182628920, gi... - gi\|182683586\|ref\|YP_001835333.1\| bifunctional methionine sulfoxide reductase A/B protein [Streptococ... gi\|194357165, gi... - gi\|194397498\|ref\|YP_002037316.1\| peptide methionine sulfoxide reductase MsrA/msrB [Streptococcus pne...	243.0	[0..4]	[145..229]

Back

Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYQKSAEAI AKLSAEQYRV TQENGTERPG TGEYLYNKEP GIYVDIVSGE PLFASSDKYE  60
   61 SHCGWPSFTK PIERANVTEL TDMSHGMVRT EVRSAHGDSH LGHVFPDGPV DRGGLRYCIN 120
  121 SASLRFVPKD RMEAEGYGDY LDQVEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.221849
Match:	1l1dA
Description:	C-terminal MsrB domain of peptide methionine sulfoxide reductase PilB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor	5.90194589149201	bayes_pls_golite062009
protein-methionine-R-oxide reductase activity	5.64196103816384	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	3.02342037380774	bayes_pls_golite062009
peptide-methionine-(S)-S-oxide reductase activity	1.80676476343543	bayes_pls_golite062009
binding	1.67290562818139	bayes_pls_golite062009
catalytic activity	0.566791077255496	bayes_pls_golite062009
nucleic acid binding	0.555078494441175	bayes_pls_golite062009
ion binding	0.415760364192452	bayes_pls_golite062009
cation binding	0.404651661251597	bayes_pls_golite062009
metal ion binding	0.404651661251597	bayes_pls_golite062009
DNA binding	0.215568693193579	bayes_pls_golite062009
transcription regulator activity	0.183261590647643	bayes_pls_golite062009
protein binding	0.0755837372617499	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: