YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|253972401, gi...
Organism:	Escherichia coli B str. REL606
Length:	663 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|253972401, gi....

Description	E-value	Query Range	Subject Range
gi\|187734130, gi... - gi\|75176905\|ref\|ZP_00697021.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Shig...	707.0	[0..1]	[663..1]
gi\|81244330, gi\|... - gi\|82542919\|ref\|YP_406866.1\| cytochrome o ubiquinol oxidase subunit I [Shigella boydii Sb227], gi\|81...	706.0	[0..1]	[663..1]
gi\|110342283, gi... - gi\|110640691\|ref\|YP_668419.1\| cytochrome o ubiquinol oxidase subunit I [Escherichia coli 536], gi\|11...	706.0	[0..1]	[663..1]
gi\|238723948, gi... - gi\|77974310\|ref\|ZP_00829851.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers...	702.0	[0..1]	[663..1]
gi\|50120081, gi\|... - gi\|50120081\|ref\|YP_049248.1\| cytochrome O ubiquinol oxidase subunit I [Pectobacterium atrosepticum S...	701.0	[0..1]	[663..1]
gi\|238791424, gi... - gi\|77979398\|ref\|ZP_00834817.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers...	698.0	[0..1]	[663..1]
gi\|166205908, gi... - gi\|166213121\|ref\|ZP_02239156.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pestis biovar An... gi\|166011062, gi... - gi\|166011062\|ref\|ZP_02231960.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pestis biovar An... gi\|167421634, gi... - gi\|167421634\|ref\|ZP_02313387.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pestis biovar Or... gi\|167399425, gi... - gi\|167399425\|ref\|ZP_02304949.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pestis biovar An... gi\|170025459, gi... - gi\|170025459\|ref\|YP_001721964.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pseudotuberculo... gi\|229695136, gi... - gi\|229838770\|ref\|ZP_04458929.1\| cytochrome o ubiquinol oxidase subunit I [Yersinia pestis biovar Ori... gi\|167057390, gi... - gi\|167423220\|ref\|ZP_02314973.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pestis biovar Me... gi\|229896076, gi... - gi\|229896076\|ref\|ZP_04511246.1\| cytochrome o ubiquinol oxidase subunit I [Yersinia pestis Pestoides ... gi\|229687740, gi... - gi\|229899338\|ref\|ZP_04514481.1\| cytochrome o ubiquinol oxidase subunit I [Yersinia pestis biovar Ori... gi\|186697344, gi... - gi\|186894318\|ref\|YP_001871430.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pseudotuberculo... gi\|77635218, gi\|... - gi\|77635218\|ref\|ZP_00797305.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers... gi\|153949620, gi... - gi\|77631920\|ref\|ZP_00794506.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers... gi\|22124927, gi\|... - gi\|22124927\|ref\|NP_668350.1\| cytochrome O ubiquinol oxidase subunit I [Yersinia pestis KIM], gi\|2195... gi\|25285455 - pir\|\|AE0384 cytochrome O ubiquinol oxidase chain I (EC 1.10.3.-) [imported] - Yersinia pestis (strai... gi\|51588583, gi\|... - gi\|51595301\|ref\|YP_069492.1\| cytochrome o ubiquinol oxidase subunit I [Yersinia pseudotuberculosis I... gi\|165926614, gi... - gi\|165926614\|ref\|ZP_02222446.1\| cytochrome o ubiquinol oxidase, subunit I [Yersinia pestis biovar Or... gi\|45435472, gi\|... - gi\|45440615\|ref\|NP_992154.1\| cytochrome O ubiquinol oxidase subunit I [Yersinia pestis biovar Microt... Q66DU2\|Q66DU2_YERPS - Cytochrome o ubiquinol oxidase subunit I - Yersinia pseudotuberculosis gi\|218930195, gi... - gi\|218930195\|ref\|YP_002348070.1\| cytochrome O ubiquinol oxidase subunit I [Yersinia pestis CO92], gi... gi\|229681247, gi... - gi\|229901318\|ref\|ZP_04516440.1\| cytochrome o ubiquinol oxidase subunit I [Yersinia pestis Nepal516],... gi\|149291402, gi... - gi\|149364989\|ref\|ZP_01887024.1\| cytochrome O ubiquinol oxidase subunit I [Yersinia pestis CA88-4125]... gi\|145211755, gi... - gi\|145600059\|ref\|YP_001164135.1\| cytochrome O ubiquinol oxidase subunit I [Yersinia pestis Pestoides... gi\|89103172, gi\|... - gi\|89103172\|ref\|ZP_01175762.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers... gi\|108808650, gi... - gi\|108808650\|ref\|YP_652566.1\| cytochrome O ubiquinol oxidase subunit I [Yersinia pestis Antiqua], gi...	695.0	[0..1]	[663..1]
gi\|37527736, gi\|... - gi\|37527736\|ref\|NP_931081.1\| ubiquinol oxidase polypeptide I (cytochrome O subunit 1) (oxidase BO(3)...	693.0	[0..1]	[663..1]
gi\|62126687, gi\|... - gi\|62179054\|ref\|YP_215471.1\| cytochrome o ubiquinol oxidase subunit I [Salmonella enterica subsp. en...	690.0	[0..1]	[663..1]
gi\|77956944, gi\|... - gi\|77956944\|ref\|ZP_00821016.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers... gi\|238720668, gi... - gi\|77962959\|ref\|ZP_00826774.1\| COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Yers...	690.0	[0..1]	[663..1]

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Predicted Domain #1

Region A:
Residues: [1-663]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGKLSLDAV PFHEPIVMVT IAGIILGGLA LVGLITYFGK WTYLWKEWLT SVDHKRLGIM  60
   61 YIIVAIVMLL RGFADAIMMR SQQALASAGE AGFLPPHHYD QIFTAHGVIM IFFVAMPFVI 120
  121 GLMNLVVPLQ IGARDVAFPF LNNLSFWFTV VGVILVNVSL GVGEFAQTGW LAYPPLSGIE 180
  181 YSPGVGVDYW IWSLQLSGIG TTLTGINFFV TILKMRAPGM TMFKMPVFTW ASLCANVLII 240
  241 ASFPILTVTV ALLTLDRYLG THFFTNDMGG NMMMYINLIW AWGHPEVYIL ILPVFGVFSE 300
  301 IAATFSRKRL FGYTSLVWAT VCITVLSFIV WLHHFFTMGA GANVNAFFGI TTMIIAIPTG 360
  361 VKIFNWLFTM YQGRIVFHSA MLWTIGFIVT FSVGGMTGVL LAVPGADFVL HNSLFLIAHF 420
  421 HNVIIGGVVF GCFAGMTYWW PKAFGFKLNE TWGKRAFWFW IIGFFVAFMP LYALGFMGMT 480
  481 RRLSQQIDPQ FHTMLMIAAS GAVLIALGIL CLVIQMYVSI RDRDQNRDLT GDPWGGRTLE 540
  541 WATSSPPPFY NFAVVPHVHE RDAFWEMKEK GEAYKKPDHY EEIHMPKNSG AGIVIAAFST 600
  601 IFGFAMIWHI WWLAIVGFAG MIITWIVKSF DEDVDYYVPV AEIEKLENQH FDEITKAGLK 660
  661 NGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1fftA
Description:	Cytochrome O ubiquinol oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
heme-copper terminal oxidase activity	14.1725811596039	bayes_pls_golite062009
cytochrome-c oxidase activity	13.8542976951523	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	13.8542976951523	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	13.8542976951523	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	7.37127314407573	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	7.21569868255501	bayes_pls_golite062009
oxidoreductase activity	7.16307962729639	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	6.59819712923927	bayes_pls_golite062009
cation transmembrane transporter activity	6.32599750294462	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	6.13181895906867	bayes_pls_golite062009
ion transmembrane transporter activity	6.1152058837897	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	5.8923420516615	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.6803770025358	bayes_pls_golite062009
substrate-specific transporter activity	5.45928453313406	bayes_pls_golite062009
cytochrome o ubiquinol oxidase activity	5.37516556135471	bayes_pls_golite062009
catalytic activity	1.95966890211023	bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity	1.51081278400602	bayes_pls_golite062009
electron carrier activity	1.29518639068237	bayes_pls_golite062009
binding	0.89004160546195	bayes_pls_golite062009
transporter activity	0.37947088637216	bayes_pls_golite062009
transmembrane transporter activity	0.36572623683433	bayes_pls_golite062009
protein binding	0.358081002328109	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: