YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254162836, gi...
Organism:	Escherichia coli B str. REL606
Length:	359 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254162836, gi....

Description	E-value	Query Range	Subject Range
gi\|26249338, gi\|... - gi\|26249338\|ref\|NP_755378.1\| fructose-bisphosphate aldolase [Escherichia coli CFT073], gi\|26109746\|g...	489.0	[0..1]	[359..29]
gi\|91073875, gi\|... - gi\|91212301\|ref\|YP_542287.1\| fructose-bisphosphate aldolase [Escherichia coli UTI89], gi\|91073875\|gb... gi\|237706430, gi... - gi\|237706430\|ref\|ZP_04536911.1\| fructose-bisphosphate aldolase class II [Escherichia sp. 3_2_53FAA],...	489.0	[0..1]	[359..29]
gi\|110616373, gi... - gi\|110806825\|ref\|YP_690345.1\| fructose-bisphosphate aldolase [Shigella flexneri 5 str. 8401], gi\|110... gi\|24114175, gi\|... - ref\|NP_708685.1\| fructose-bisphosphate aldolase, class II [Shigella flexneri 2a str. 301], gb\|AAN44...	488.0	[0..1]	[359..29]
gi\|25291095 - gi\|25291095\|pir\|\|G85948 fructose-bisphosphate aldolase, class II [imported] - Escherichia coli (stra... gi\|12517457, gi\|... - gi\|15803459\|ref\|NP_289492.1\| fructose-bisphosphate aldolase [Escherichia coli O157:H7 EDL933], gi\|12...	488.0	[0..1]	[359..26]
gi\|161365389, gi... - gi\|161616025\|ref\|YP_001589990.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|62181580, gi\|... - gi\|62181580\|ref\|YP_217997.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ser...	486.0	[0..1]	[359..26]
gi\|115514274, gi... - gi\|117625150\|ref\|YP_854138.1\| fructose-bisphosphate aldolase [Escherichia coli APEC O1], gi\|11551427... gi\|218559912, gi... - gi\|218559912\|ref\|YP_002392825.1\| fructose-bisphosphate aldolase [Escherichia coli S88], gi\|218366681... gi\|191171839, gi... - gi\|75241282\|ref\|ZP_00725144.1\| COG0191: Fructose/tagatose bisphosphate aldolase [Escherichia coli F1... gi\|218428608, gi... - gi\|218691044\|ref\|YP_002399256.1\| fructose-bisphosphate aldolase [Escherichia coli ED1a], gi\|21842860... gi\|161486130 - gi\|161486130\|ref\|NP_755378.2\| fructose-bisphosphate aldolase [Escherichia coli CFT073] gi\|227888472, gi... - gi\|227888472\|ref\|ZP_04006277.1\| fructose-bisphosphate aldolase [Escherichia coli 83972], gi\|22783474... gi\|215488218, gi... - gi\|215488218\|ref\|YP_002330649.1\| fructose-bisphosphate aldolase [Escherichia coli O127:H6 str. E2348...	485.0	[0..1]	[359..1]
gi\|187731854, gi... - gi\|75178821\|ref\|ZP_00698857.1\| COG0191: Fructose/tagatose bisphosphate aldolase [Shigella boydii BS5... gi\|81246866, gi\|... - gi\|82545455\|ref\|YP_409402.1\| fructose-bisphosphate aldolase [Shigella boydii Sb227], gi\|81246866\|gb\|...	484.0	[0..1]	[359..1]
lcl\|NC_016856.1_... - [gene=fba] [protein=fructose-bisphosphate aldolase] [protein_id=YP_005239211.1] [location=complement... gi\|194468591, gi... - gi\|194468591\|ref\|ZP_03074575.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|194451269, gi... - gi\|194451269\|ref\|YP_002047055.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|194402962, gi... - gi\|194444299\|ref\|YP_002042322.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|168463754, gi... - gi\|195633612\|gb\|EDX52026.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica sero... gi\|198243554, gi... - gi\|198243554\|ref\|YP_002217046.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|197363943, gi... - gi\|197363943\|ref\|YP_002143580.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|197261871, gi... - gi\|197261871\|ref\|ZP_03161945.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|197212666, gi... - gi\|197248963\|ref\|YP_002147982.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|205322286, gi... - gi\|205322286\|gb\|EDZ10125.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica sero... gi\|162139549 - gi\|162139549\|ref\|YP_217997.2\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica se... gi\|168264495, gi... - gi\|205347036\|gb\|EDZ33667.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica sero... gi\|168242862, gi... - gi\|205338132\|gb\|EDZ24896.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica sero... gi\|205331742, gi... - gi\|205331742\|gb\|EDZ18506.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica sero... gi\|205331266, gi... - gi\|205331266\|gb\|EDZ18030.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica sero... gi\|16504152, gi\|... - gi\|25291103\|pir\|\|AC0875 fructose 1,6-bisphosphate aldolase [imported] - Salmonella enterica subsp. e... gi\|16766369, gi\|... - gi\|16766369\|ref\|NP_461984.1\| fructose-bisphosphate aldolase [Salmonella typhimurium LT2], gi\|1642162... gi\|224469388, gi... - gi\|224584861\|ref\|YP_002638659.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|214000158 - gi\|214000158\|ref\|ZP_03410893.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|213850200 - gi\|213850200\|ref\|ZP_03381098.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|29143337, gi\|... - gi\|29143337\|ref\|NP_806679.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ser... gi\|16761850 - gi\|16761850\|ref\|NP_457467.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ser... gi\|206710134, gi... - gi\|207858331\|ref\|YP_002244982.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|205273773, gi... - gi\|205353992\|ref\|YP_002227793.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|204322428, gi... - gi\|204928106\|ref\|ZP_03219306.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|199606004, gi... - gi\|200388906\|ref\|ZP_03215518.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|213650822 - gi\|213650822\|ref\|ZP_03380875.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|213609090 - gi\|213609090\|ref\|ZP_03368916.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|56415014, gi\|... - gi\|56415014\|ref\|YP_152089.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ser... gi\|213423668 - gi\|213423668\|ref\|ZP_03356648.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|213051770 - gi\|213051770\|ref\|ZP_03344648.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ... gi\|229307086 - gi\|229307086\|ref\|YP_001589990.2\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica... gi\|238909868 - gi\|238909868\|ref\|ZP_04653705.1\| fructose-bisphosphate aldolase [Salmonella enterica subsp. enterica ...	481.0	[0..1]	[359..1]
ALF_ECOLI - (P0AB71) Fructose-bisphosphate aldolase class 2 (EC 4.1.2.13) (Fructose-bisphosphate aldolase class ... ALF_ECO57 - (P0AB72) Fructose-bisphosphate aldolase class 2 (EC 4.1.2.13) (Fructose-bisphosphate aldolase class ... ALF_SHIFL - (P0AB73) Fructose-bisphosphate aldolase class 2 (EC 4.1.2.13) (Fructose-bisphosphate aldolase class ...	480.0	[0..2]	[359..1]
gi\|115346704, gi... - gi\|218928093\|ref\|YP_002345968.1\| fructose-bisphosphate aldolase [Yersinia pestis CO92], gi\|16121225\|... gi\|165937243, gi... - gi\|89104325\|ref\|ZP_01176871.1\| COG0191: Fructose/tagatose bisphosphate aldolase [Yersinia pestis bio... gi\|108806341, gi... - gi\|108806341\|ref\|YP_650257.1\| fructose-bisphosphate aldolase [Yersinia pestis Antiqua], gi\|108778254... gi\|229690916, gi... - gi\|229842606\|ref\|ZP_04462761.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ori... gi\|229697200, gi... - gi\|229840834\|ref\|ZP_04460993.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ori... gi\|229837610, gi... - gi\|229837610\|ref\|ZP_04457772.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis Pestoides ... gi\|108776927, gi... - gi\|229903738\|ref\|ZP_04518851.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis Nepal516],... gi\|165990778, gi... - gi\|166010292\|ref\|ZP_02231190.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ant... gi\|166205963, gi... - gi\|166212671\|ref\|ZP_02238706.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ant... gi\|167050763, gi... - gi\|167400055\|ref\|ZP_02305573.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ant... gi\|166962784, gi... - gi\|167418790\|ref\|ZP_02310543.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ori... gi\|167425361, gi... - gi\|167425361\|ref\|ZP_02317114.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Med... gi\|169749636, gi... - gi\|170023102\|ref\|YP_001719607.1\| fructose-bisphosphate aldolase [Yersinia pseudotuberculosis YPIII],... gi\|145209596, gi... - gi\|145597900\|ref\|YP_001161976.1\| fructose-bisphosphate aldolase [Yersinia pestis Pestoides F], gi\|14... gi\|149290684, gi... - gi\|149367070\|ref\|ZP_01889103.1\| fructose-bisphosphate aldolase class II [Yersinia pestis CA88-4125],... gi\|25291105 - pir\|\|AI0112 fructose-bisphosphate aldolase (EC 4.1.2.13) [imported] - Yersinia pestis (strain CO92) gi\|45438126, gi\|... - gi\|45443258\|ref\|NP_994797.1\| fructose-bisphosphate aldolase [Yersinia pestis biovar Microtus str. 91... gi\|77635848, gi\|... - gi\|77635848\|ref\|ZP_00797928.1\| COG0191: Fructose/tagatose bisphosphate aldolase [Yersinia pestis Ang... gi\|22127183, gi\|... - gi\|22127183\|ref\|NP_670606.1\| fructose-bisphosphate aldolase [Yersinia pestis KIM], gi\|21960247\|gb\|AA... gi\|117672603, gi... - gi\|77630172\|ref\|ZP_00792758.1\| COG0191: Fructose/tagatose bisphosphate aldolase [Yersinia pseudotube... gi\|165923161, gi... - gi\|165924961\|ref\|ZP_02220793.1\| fructose-bisphosphate aldolase, class II [Yersinia pestis biovar Ori...	479.0	[0..1]	[359..1]

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Predicted Domain #1

Region A:
Residues: [1-359]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKIFDFVKP GVITGDDVQK VFQVAKENNF ALPAVNCVGT DSINAVLETA AKVKAPVIVQ  60
   61 FSNGGASFIA GKGVKSDVPQ GAAILGAISG AHHVHQMAEH YGVPVILHTD HCAKKLLPWI 120
  121 DGLLDAGEKH FAATGKPLFS SHMIDLSEES LQENIEICSK YLERMSKIGM TLEIELGCTG 180
  181 GEEDGVDNSH MDASALYTQP EDVDYAYTEL SKISPRFTIA ASFGNVHGVY KPGNVVLTPT 240
  241 ILRDSQEYVS KKHNLPHNSL NFVFHGGSGS TAQEIKDSVS YGVVKMNIDT DTQWATWEGV 300
  301 LNYYKANEAY LQGQLGNPKG EDQPNKKYYD PRVWLRAGQT SMIARLEKAF QELNAIDVL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1b57A
Description:	Fructose-bisphosphate aldolase (FBP aldolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	2.5119145652386	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.0240718059985	bayes_pls_golite062009
transaldolase activity	1.66628808988861	bayes_pls_golite062009
binding	1.1388634428163	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
signal transducer activity	0.348681535897548	bayes_pls_golite062009
molecular transducer activity	0.348681535897548	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.25728790872659	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: