YRC Public Data Repository - Protein Structure Prediction

Protein:	FDHD_ECOBW
Organism:	Escherichia coli BW2952
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FDHD_ECOBW.

Description	E-value	Query Range	Subject Range
gi\|24115189, gi\|... - gi\|24115189\|ref\|NP_709699.1\| formate dehydrogenase accessory protein [Shigella flexneri 2a str. 301]... FDHD_SHIF8 - Sulfurtransferase FdhD OS=Shigella flexneri serotype 5b (strain 8401) GN=fdhD PE=3 SV=1 gi\|30064812, gi\|... - gi\|30064812\|ref\|NP_838983.1\| formate dehydrogenase accessory protein [Shigella flexneri 2a str. 2457... FDHD_SHIFL - Sulfurtransferase FdhD OS=Shigella flexneri GN=fdhD PE=3 SV=1	373.0	[0..1]	[277..1]
gi\|75188631 - gi\|75188631\|ref\|ZP_00701898.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a... gi\|75230417 - gi\|75230417\|ref\|ZP_00716903.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a... gi\|75211290 - gi\|75211290\|ref\|ZP_00711389.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a... gi\|75258121 - gi\|75258121\|ref\|ZP_00729582.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a... FDHD_ECO5E - Sulfurtransferase FdhD OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=fdhD PE=3 SV=1 gi\|195937536 - gi\|195937536\|ref\|ZP_03082918.1\| formate dehydrogenase accessory protein [Escherichia coli O157:H7 st... FDHD_ECO57 - Sulfurtransferase FdhD OS=Escherichia coli O157:H7 GN=fdhD PE=3 SV=1 gi\|237702928, gi... - gi\|237702928\|ref\|ZP_04533409.1\| fdhD [Escherichia sp. 3_2_53FAA], gi\|226902865\|gb\|EEH89124.1\| fdhD [... FDHD_ECO45 - Sulfurtransferase FdhD OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=fdhD PE=3 SV=1 FDHD_ECOSE - Sulfurtransferase FdhD OS=Escherichia coli (strain SE11) GN=fdhD PE=3 SV=1 gi\|254795891, gi... - gi\|254795891\|ref\|YP_003080728.1\| formate dehydrogenase formation protein [Escherichia coli O157:H7 s... FDHD_ECO55 - Sulfurtransferase FdhD OS=Escherichia coli (strain 55989 / EAEC) GN=fdhD PE=3 SV=1 FDHD_ECO81 - Sulfurtransferase FdhD OS=Escherichia coli O81 (strain ED1a) GN=fdhD PE=3 SV=1 FDHD_ECOK1 - Sulfurtransferase FdhD OS=Escherichia coli O1:K1 / APEC GN=fdhD PE=3 SV=1 FDHD_ECOLU - Sulfurtransferase FdhD OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=fdhD PE=3 SV=1 FDHD_ECO7I - Sulfurtransferase FdhD OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=fdhD PE=3 SV=1 gi\|15834075, gi\|... - gi\|15834075\|ref\|NP_312848.1\| formate dehydrogenase accessory protein [Escherichia coli O157:H7 str. ... gi\|12518787, gi\|... - gi\|15804484\|ref\|NP_290524.1\| formate dehydrogenase accessory protein [Escherichia coli O157:H7 EDL93... gi\|209752552, gi... - gi\|25345620\|pir\|\|D86078 affects formate dehydrogenase-N [imported] - Escherichia coli (strain O157:H... FDHD_ECOUT - Sulfurtransferase FdhD OS=Escherichia coli (strain UTI89 / UPEC) GN=fdhD PE=3 SV=1	372.0	[0..1]	[277..1]
gi\|75237859 - gi\|75237859\|ref\|ZP_00721874.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a... FDHD_ECOL5 - Sulfurtransferase FdhD OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=fdhD PE=3 SV=1	371.0	[0..1]	[277..1]
gi\|83586257 - gi\|83586257\|ref\|ZP_00924893.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a... gi\|254163845, gi... - gi\|254163845\|ref\|YP_003046953.1\| formate dehydrogenase accessory protein [Escherichia coli B str. RE... gi\|253326511, gi... - gi\|254290596\|ref\|YP_003056344.1\| formate dehydrogenase accessory protein [Escherichia coli BL21(DE3)... gi\|251787158, gi... - gi\|251787158\|ref\|YP_003001462.1\| hypothetical protein B21_03729 [Escherichia coli BL21], gi\|24237943...	370.0	[0..1]	[277..1]
gi\|227837621, gi... - gi\|227885363\|ref\|ZP_04003168.1\| formate dehydrogenase accessory protein [Escherichia coli 83972], gi... FDHD_ECOL6 - Protein FdhD OS=Escherichia coli O6 GN=fdhD PE=3 SV=1 FDHD_ECOL6 - Sulfurtransferase FdhD OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=fdhD PE=3 S...	370.0	[0..1]	[277..1]
gi\|194433232, gi... - gi\|83569840\|ref\|ZP_00921289.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a...	370.0	[0..1]	[277..1]
FDHD_SHIDS - Sulfurtransferase FdhD OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=fdhD PE=3 SV=1	368.0	[0..1]	[277..1]
gi\|77973735 - gi\|77973735\|ref\|ZP_00829280.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a...	344.0	[0..2]	[275..9]
gi\|167055577, gi... - gi\|167425563\|ref\|ZP_02317316.1\| aerobic formate dehydrogenase accessory protein [Yersinia pestis bio... gi\|166009482, gi... - gi\|166009482\|ref\|ZP_02230380.1\| aerobic formate dehydrogenase accessory protein [Yersinia pestis bio... gi\|165915104, gi... - gi\|165936862\|ref\|ZP_02225428.1\| aerobic formate dehydrogenase accessory protein [Yersinia pestis bio... gi\|167421088, gi... - gi\|167421088\|ref\|ZP_02312841.1\| aerobic formate dehydrogenase accessory protein [Yersinia pestis bio... gi\|166213328, gi... - gi\|166213328\|ref\|ZP_02239363.1\| aerobic formate dehydrogenase accessory protein [Yersinia pestis bio... FDHD_YERPE - Sulfurtransferase FdhD OS=Yersinia pestis GN=fdhD PE=3 SV=2 FDHD_YERPN - Sulfurtransferase FdhD OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=fdhD PE=3 SV=1 FDHD_YERPA - Sulfurtransferase FdhD OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=fdhD PE=3 SV=1 gi\|165926062, gi... - gi\|165926062\|ref\|ZP_02221894.1\| aerobic formate dehydrogenase accessory protein [Yersinia pestis bio... FDHD_YERPG - Sulfurtransferase FdhD OS=Yersinia pestis bv. Antiqua (strain Angola) GN=fdhD PE=3 SV=1 gi\|229700265, gi... - gi\|229896726\|ref\|ZP_04511890.1\| formate dehydrogenase formation protein [Yersinia pestis Pestoides A... gi\|150260999, gi... - gi\|150260999\|ref\|ZP_01917727.1\| putative formate dehydrogenase [Yersinia pestis CA88-4125], gi\|14929... gi\|229839764, gi... - gi\|229839764\|ref\|ZP_04459923.1\| formate dehydrogenase formation protein [Yersinia pestis biovar Orie... FDHD_YERPP - Sulfurtransferase FdhD OS=Yersinia pestis (strain Pestoides F) GN=fdhD PE=3 SV=1 gi\|229691187, gi... - gi\|229841848\|ref\|ZP_04462004.1\| formate dehydrogenase formation protein [Yersinia pestis biovar Orie...	344.0	[0..1]	[276..1]
gi\|77960724 - gi\|77960724\|ref\|ZP_00824583.1\| COG1526: Uncharacterized protein required for formate dehydrogenase a...	343.0	[0..2]	[275..9]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTQRKEIE NVTNITGVRQ IELWRRDDLQ HPRLDEVAEE VPVALVYNGI SHVVMMASPK  60
   61 DLEYFALGFS LSEGIIESPR DIFGMDVVPS CNGLEVQIEL SSRRFMGLKE RRRALAGRTG 120
  121 CGVCGVEQLN DIGKPVQPLP FTQTFDLNKL DDALRHLNDF QPVGQLTGCT HAAAWMLPSG 180
  181 ELVGGHEDVG RHVALDKLLG RRSQEGESWQ QGAVLVSSRA SYEMVQKSAM CGVEILFAVS 240
  241 AATTLAVEVA ERCNLTLVGF CKPGRATVYT HPQRLSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.045757
Match:	2pw9A
Description:	No description for 2pw9A was found.

Predicted functions:

Term	Confidence	Notes
formate dehydrogenase activity	11.6538357294979	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6.39976727113281	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	5.99996975993203	bayes_pls_golite062009
oxidoreductase activity	3.97029744496041	bayes_pls_golite062009
methyltransferase activity	1.82461172360024	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.74440766585265	bayes_pls_golite062009
catalytic activity	1.70756445127105	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1.25933001876793	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	1.14540769627856	bayes_pls_golite062009
electron carrier activity	0.851003321957332	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: