YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|229696545, gi...
Organism:	Yersinia pestis biovar Orientalis str. PEXU2
Length:	202 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229696545, gi....

Description	E-value	Query Range	Subject Range
gi\|2293118 - gi\|2293118\|gb\|AAB68649.1\| LexA [unidentified cloning vector]	4.0E-57	[1..202]	[1..202]
gi\|200388085, gi... - gi\|200388085\|ref\|ZP_03214697.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Virchow ... LEXA_SALDC - LexA repressor OS=Salmonella dublin (strain CT_02021853) GN=lexA PE=3 SV=1 LEXA_SALPK - LexA repressor OS=Salmonella paratyphi A (strain AKU_12601) GN=lexA PE=3 SV=1 gi\|197241491, gi... - gi\|197263236\|ref\|ZP_03163310.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Saintpau... gi\|213052230 - gi\|213052230\|ref\|ZP_03345108.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALEP - LexA repressor OS=Salmonella enteritidis PT4 (strain P125109) GN=lexA PE=3 SV=1 LEXA_SALG2 - LexA repressor OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=lexA PE=3 SV=1 gi\|204927146, gi... - gi\|204927146\|ref\|ZP_03218348.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Javiana ... LEXA_SALNS - LexA repressor OS=Salmonella newport (strain SL254) GN=lexA PE=3 SV=1 gi\|195630596, gi... - gi\|195630596\|gb\|EDX49208.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Newport str.... gi\|205347902, gi... - gi\|205347902\|gb\|EDZ34533.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Hadar str. R... gi\|205337302, gi... - gi\|205337302\|gb\|EDZ24066.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Heidelberg s... LEXA_SALA4 - LexA repressor OS=Salmonella agona (strain SL483) GN=lexA PE=3 SV=1 LEXA_SALSV - LexA repressor OS=Salmonella schwarzengrund (strain CVM19633) GN=lexA PE=3 SV=1 gi\|194472176, gi... - gi\|194472176\|ref\|ZP_03078160.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Kentucky... LEXA_SALHS - LexA repressor OS=Salmonella heidelberg (strain SL476) GN=lexA PE=3 SV=1 LEXA_SALPB - LexA repressor OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=lexA PE=3 SV=1 LEXA_SALAR - LexA repressor OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) GN=lexA PE=3 SV=1 LEXA_SALCH - LexA repressor OS=Salmonella choleraesuis (strain SC-B67) GN=lexA PE=3 SV=1 LEXA_SALPA - LexA repressor OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=lexA PE=3 SV=1 gi\|213647510 - gi\|213647510\|ref\|ZP_03377563.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... gi\|213619392 - gi\|213619392\|ref\|ZP_03373218.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALTI - LexA repressor OS=Salmonella typhi GN=lexA PE=3 SV=1 gi\|213424504 - gi\|213424504\|ref\|ZP_03357301.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALTI - LexA repressor OS=Salmonella typhi GN=lexA PE=3 SV=1 gi\|213423564 - gi\|213423564\|ref\|ZP_03356544.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... LEXA_SALTY - LexA repressor OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=lexA PE=3 SV=1 gi\|29144405, gi\|... - gi\|29144405\|ref\|NP_807747.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi str. ... LEXA_SALPC - LexA repressor OS=Salmonella paratyphi C (strain RKS4594) GN=lexA PE=3 SV=1 gi\|16762918 - gi\|16762918\|ref\|NP_458535.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi str. ... gi\|214000133 - gi\|214000133\|ref\|ZP_03410868.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... gi\|213859894 - gi\|213859894\|ref\|ZP_03385598.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Typhi st... gi\|238913014 - gi\|238913014\|ref\|ZP_04656851.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Tennesse... LEXA_SALCH - LexA repressor OS=Salmonella choleraesuis GN=lexA PE=3 SV=1 LEXA_SALTY - LexA repressor OS=Salmonella typhimurium GN=lexA PE=3 SV=1 gi\|168239348, gi... - gi\|197287939\|gb\|EDY27327.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Schwarzengru... LEXA_SALPB - LexA repressor OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=lexA PE=3 SV=1 gi\|205334379, gi... - gi\|205334379\|gb\|EDZ21143.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Kentucky str... gi\|205330205, gi... - gi\|205330205\|gb\|EDZ16969.1\| LexA repressor [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-... gi\|205322831, gi... - gi\|205322831\|gb\|EDZ10670.1\| LexA repressor [Salmonella enterica subsp. enterica serovar Saintpaul st... LEXA_SALCH - LexA repressor OS=Salmonella choleraesuis GN=lexA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=lexA] [protein=LexA repressor] [protein_id=YP_005240529.1] [location=4472790..4473398] LEXA_SALPA - LexA repressor OS=Salmonella paratyphi A GN=lexA PE=3 SV=1 LEXA_SALTY - LexA repressor OS=Salmonella typhimurium GN=lexA PE=3 SV=1	1.0E-56	[1..202]	[1..202]
gi\|89110764, gi\|... - gi\|89110764\|ref\|AP_004544.1\| DNA-binding transcriptional repressor [Escherichia coli str. K-12 subst... gi\|254796045, gi... - gi\|254796045\|ref\|YP_003080882.1\| DNA-binding transcriptional repressor of SOS regulon [Escherichia c... gi\|253975880, gi... - gi\|254163979\|ref\|YP_003047087.1\| LexA repressor [Escherichia coli B str. REL606], gi\|253975880\|gb\|AC... LEXA_SHIDS - LexA repressor OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=lexA PE=3 SV=1 LEXA_ECOUT - LexA repressor OS=Escherichia coli (strain UTI89 / UPEC) GN=lexA PE=3 SV=1 gi\|254037039, gi... - gi\|254037039\|ref\|ZP_04871116.1\| LexA repressor [Escherichia sp. 1_1_43], gi\|226840145\|gb\|EEH72147.1\|... LEXA_SHIBS - LexA repressor OS=Shigella boydii serotype 4 (strain Sb227) GN=lexA PE=3 SV=1 gi\|13364503, gi\|... - gi\|15834280\|ref\|NP_313053.1\| LexA repressor [Escherichia coli O157:H7 str. Sakai], gi\|13364503\|dbj\|B... gi\|253775329, gi... - gi\|254290729\|ref\|YP_003056477.1\| LexA repressor [Escherichia coli BL21(DE3)], gi\|253980036\|gb\|ACT457... gi\|251787299, gi... - gi\|251787299\|ref\|YP_003001603.1\| hypothetical protein B21_03875 [Escherichia coli BL21], gi\|24237957... LEXA_ECOBW - LexA repressor OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=lexA PE=3 SV=1 gi\|237703600, gi... - gi\|237703600\|ref\|ZP_04534081.1\| regulator for SOS(lexA) regulon [Escherichia sp. 3_2_53FAA], gi\|2269... gi\|227886951, gi... - gi\|227886951\|ref\|ZP_04004756.1\| repressor lexA [Escherichia coli 83972], gi\|227836092\|gb\|EEJ46558.1\|... gi\|75229390, gi\|... - gi\|75229390\|ref\|ZP_00715942.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|75238581, gi\|... - gi\|75238581\|ref\|ZP_00722570.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_ECOHS - LexA repressor OS=Escherichia coli O9:H4 (strain HS) GN=lexA PE=3 SV=1 gi\|194426760, gi... - gi\|75211926\|ref\|ZP_00711981.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|188495882, gi... - gi\|75514804\|ref\|ZP_00737033.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_ECOL5 - LexA repressor OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=lexA PE=3 SV=1 LEXA_SHISS - LexA repressor OS=Shigella sonnei (strain Ss046) GN=lexA PE=3 SV=1 LEXA_SHIF8 - LexA repressor OS=Shigella flexneri serotype 5b (strain 8401) GN=lexA PE=3 SV=1 gi\|190907727, gi... - gi\|75241073\|ref\|ZP_00724947.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|75258963, gi\|... - gi\|75258963\|ref\|ZP_00730331.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... LEXA_SHIB3 - LexA repressor OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=lexA PE=3 SV=1 LEXA_ECO24 - LexA repressor OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=lexA PE=3 SV=1 gi\|194437208, gi... - gi\|83587136\|ref\|ZP_00925765.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... sp\|B7UPK4\|LEXA_ECO27 - LexA repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=lexA PE=3 SV=1 LEXA_ECOL6 - LexA repressor OS=Escherichia coli O6 GN=lexA PE=3 SV=1 LEXA_ECO27 - LexA repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=lexA PE=3 SV=1 gi\|217325242, gi... - gi\|217325242\|ref\|ZP_03441326.1\| LexA repressor [Escherichia coli O157:H7 str. TW14588], gi\|217321463... LEXA_ECO8A - LexA repressor OS=Escherichia coli O8 (strain IAI1) GN=lexA PE=3 SV=1 LEXA_ECO45 - LexA repressor OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=lexA PE=3 SV=1 LEXA_ECO81 - LexA repressor OS=Escherichia coli O81 (strain ED1a) GN=lexA PE=3 SV=1 LEXA_ECO55 - LexA repressor OS=Escherichia coli (strain 55989 / EAEC) GN=lexA PE=3 SV=1 LEXA_ECO7I - LexA repressor OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=lexA PE=3 SV=1 LEXA_ECOLU - LexA repressor OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=lexA PE=3 SV=1 LEXA_ECOLC - LexA repressor OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=lexA PE=3 SV=1 LEXA_ECOSM - LexA repressor OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=lexA PE=3 SV=1 gi\|170769501, gi... - gi\|170769501\|ref\|ZP_02903954.1\| LexA repressor [Escherichia albertii TW07627], gi\|170121558\|gb\|EDS90... gi\|195935810 - gi\|195935810\|ref\|ZP_03081192.1\| LexA repressor [Escherichia coli O157:H7 str. EC4024] gi\|208725781, gi... - gi\|208805980\|ref\|ZP_03248317.1\| LexA repressor [Escherichia coli O157:H7 str. EC4206], gi\|208725781\|... LEXA_ECOK1 - LexA repressor OS=Escherichia coli O1:K1 / APEC GN=lexA PE=3 SV=1 gi\|208812141, gi... - gi\|208812141\|ref\|ZP_03253470.1\| LexA repressor [Escherichia coli O157:H7 str. EC4045], gi\|208733418\|... gi\|124501126, gi... - gi\|124527683\|ref\|ZP_01699118.1\| SOS-response transcriptional repressor, LexA [Escherichia coli B], g... gi\|208738799, gi... - gi\|208818676\|ref\|ZP_03258996.1\| LexA repressor [Escherichia coli O157:H7 str. EC4042], gi\|208738799\|... LEXA_ECO5E - LexA repressor OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=lexA PE=3 SV=1 LEXA_ECOSE - LexA repressor OS=Escherichia coli (strain SE11) GN=lexA PE=3 SV=1 LEXA_ECOLI - LexA repressor (EC 3.4.21.88) - Escherichia coli gi\|168755195, gi... - gi\|189357457\|gb\|EDU75876.1\| LexA repressor [Escherichia coli O157:H7 str. EC4401], gi\|168755195\|ref\|... gi\|189368539, gi... - gi\|189368539\|gb\|EDU86955.1\| LexA repressor [Escherichia coli O157:H7 str. EC4501], gi\|168760890\|ref\|... gi\|189364225, gi... - gi\|189364225\|gb\|EDU82644.1\| LexA repressor [Escherichia coli O157:H7 str. EC4486], gi\|168766285\|ref\|... LEXA_SHIFL - LexA repressor OS=Shigella flexneri GN=lexA PE=3 SV=1 gi\|187769832, gi... - gi\|187769832\|gb\|EDU33676.1\| LexA repressor [Escherichia coli O157:H7 str. EC4196], gi\|168774382\|ref\|... gi\|24054674, gi\|... - gi\|24115367\|ref\|NP_709877.1\| LexA repressor [Shigella flexneri 2a str. 301], gi\|24054674\|gb\|AAN45584... gi\|189001764, gi... - gi\|189001764\|gb\|EDU70750.1\| LexA repressor [Escherichia coli O157:H7 str. EC4076], gi\|168780437\|ref\|... EG10533 - transcriptional repressor of SOS regulon / Global regulator (repressor) for SOS regulon; dimeric LEXA_ECOL6 - LexA repressor OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=lexA PE=3 SV=1 gi\|189375044, gi... - gi\|189375044\|gb\|EDU93460.1\| LexA repressor [Escherichia coli O157:H7 str. EC869], gi\|168784640\|ref\|Z... gi\|30064633, gi\|... - gi\|30064633\|ref\|NP_838804.1\| LexA repressor [Shigella flexneri 2a str. 2457T], gi\|30042892\|gb\|AAP186... gi\|168798312, gi... - gi\|189379093\|gb\|EDU97509.1\| LexA repressor [Escherichia coli O157:H7 str. EC508], gi\|168798312\|ref\|Z... LEXA_ECO57 - LexA repressor OS=Escherichia coli O157:H7 GN=lexA PE=3 SV=1 LEXA_ECODH - LexA repressor OS=Escherichia coli (strain K12 / DH10B) GN=lexA PE=3 SV=1 EG10533 - transcriptional repressor of SOS regulon / Global regulator (repressor) for SOS regulon; dimeric gi\|15804636, gi\|... - gi\|15804636\|ref\|NP_290677.1\| LexA repressor [Escherichia coli O157:H7 EDL933], gi\|12518992\|gb\|AAG592... gi\|188015015, gi... - gi\|188015015\|gb\|EDU53137.1\| LexA repressor [Escherichia coli O157:H7 str. EC4113], gi\|168750824\|ref\|...	1.0E-56	[1..202]	[1..202]
gi\|15988319, gi\|... - gi\|15988319\|pdb\|1JHF\|B Chain B, Lexa G85d Mutant, gi\|15988318\|pdb\|1JHF\|A Chain A, Lexa G85d Mutant	2.0E-56	[1..202]	[1..202]
gi\|47768, gi\|552... - pir\|\|ILEBT lexA protein - Salmonella typhimurium, gi\|552020\|gb\|AAA27157.1\| lexA [Salmonella enteric... gi\|47768\|emb\|CAA... - lexA, LexA protein [Salmonella typhimurium]	2.0E-56	[1..202]	[1..202]
gi\|77961099, gi\|... - gi\|77961099\|ref\|ZP_00824946.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|238764118, gi... - gi\|238764118\|ref\|ZP_04625072.1\| LexA repressor [Yersinia kristensenii ATCC 33638], gi\|238697655\|gb\|E...	2.0E-55	[1..202]	[1..202]
LEXA_YERE8 - LexA repressor OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) GN=le... gi\|238716119, gi... - gi\|77957500\|ref\|ZP_00821554.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|238701485, gi... - gi\|238760283\|ref\|ZP_04621426.1\| LexA repressor [Yersinia aldovae ATCC 35236], gi\|238701485\|gb\|EEP940...	4.0E-55	[1..202]	[1..202]
gi\|77977114, gi\|... - gi\|77977114\|ref\|ZP_00832572.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop...	4.0E-55	[1..202]	[1..202]
LEXA_AERHY - (Q44069) LexA repressor (EC 3.4.21.88)	8.0E-55	[1..202]	[1..207]

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Predicted Domain #1

Region A:
Residues: [1-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALTTRQQE VYDLVRDHLA QTGMPPTRAE IAQRLGFRSP NAAEEHLKAL ARKGVIEIVS  60
   61 GASRGIRLLM EEEEGLPLIG RVAAGEPLLA QQHIEGHYKV DPSLFKPGAD FLLRVNGMSM 120
  121 RDIGILDGDL LAVHKTQDVR NGQVVVARID DEVTVKRLKK QGNIVHLLPE NSEFQPIVVD 180
  181 LREQSFTIEG LAVGVIRNGD WI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	1jhfA
Description:	LexA repressor, N-terminal DNA-binding domain; LexA C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.30784351115827	bayes_pls_golite062009
nucleic acid binding	0.603302373860066	bayes_pls_golite062009
DNA binding	0.452668330421957	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
binding	0.355412070907203	bayes_pls_golite062009
transcription factor activity	0.0554645717043947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: